Organization
Research Institute of Environmental Medicine Division of Stress Recognition and Response Designated assistant professor
Title
Designated assistant professor
External link
YAMAGUCHI Hiroshi
Degree 1
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理学博士 （ 2009.3 大阪大学 ）
Research Interests 1
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冬眠
Research Areas 2
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Life Science / Cell biology
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Life Science / Molecular biology
Research History 4
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名古屋大学環境医学研究所 神経系調節分野II 特任助教
2019.6
Country：Japan
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Stanford University Department of Psychiatry and Behavioral sciences Postdoctoral fellow
2015.5 - 2019.5
Country：Japan
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京都大学大学院医学研究科 医化学 助教
2011.11 - 2015.3
Country：Japan
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京都大学大学院医学研究科 医化学 特定研究員
2009.4 - 2011.10
Country：Japan
Education 2
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Osaka University
2004.4 - 2009.3
Country： Japan
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The University of Tokyo Faculty of Agriculture
2000.4 - 2004.3
Country： Japan
Professional Memberships 2
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日本免疫学会
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日本生化学会
Papers 9
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In vivo cell type-specific CRISPR gene editing for sleep research Reviewed International coauthorship
Hiroshi Yamaguchi, Luis de lecea
Bio-protocol 2019.8
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In vivo cell type-specific CRISPR gene editing for sleep research Invited Reviewed
Hiroshi Yamaguchi, Luis de lecea
Journal of Neuroscience Methods 2019.3
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In vivo cell type-specific CRISPR knockdown of dopamine beta-hydroxylase reduces locus coeruleus evoked wakefulness. Invited Reviewed
Hiroshi Yamaguchi, F. Woodward Hopf, Shi-bin Li, Luis de lecea
Nature Communications 2018.12
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Cardiac myofibroblast engulfment of dead cells facilitates recovery after myocardial infarction Invited Reviewed
Michio Nakaya, Kenji Watari, Mitsuru Tajima, Takeo Nakaya, Shoichi Matsuda, Hiroki Ohara, Hiroaki Nishihara, Hiroshi Yamaguchi, Akiko Hashimoto, Mitsuho Nishida, Akiomi Nagasaka, Yuma Horii, Hiroki Ono, Gentaro Iribe, Ryuji Inoue, Makoto Tsuda, Kazuhide Inoue, Akira Tanaka, Masahiko Kuroda, Shigekazu Nagata, Hitoshi Kurose
The Journal of Clinical Investigation 2017.11
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Immunosuppression via adenosine receptor activation by adenosine monophosphate released from apoptotic cells Invited Reviewed
Hiroshi Yamaguchi, Toshihiko Maruyama, Yoshihiro Urade, Shigekazu Nagata
eLife 2014.3
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Serum milk fat globule epidermal growth factor 8 elevation may subdivide systemic lupus erythematosus into two pathophysiologically distinct subsets Invited Reviewed
N Yamamoto 1, H Yamaguchi, K Ohmura, T Yokoyama, H Yoshifuji, N Yukawa, D Kawabata, T Fujii, S Morita, S Nagata, T Mimori
Lupus 2014.2
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Milk fat globule-EGF factor 8 mediates the enhancement of apoptotic cell clearance by glucocorticoids Invited Reviewed
K Lauber, H Keppeler, L E Munoz, U Koppe, K Schröder, H Yamaguchi, G Krönke, S Uderhardt, S Wesselborg, C Belka, S Nagata, M Herrmann
Cell Death Differ . 2013.9
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Aberrant splicing of the milk fat globule-EGF factor 8 (MFG-E8) gene in human systemic lupus erythematosus Invited Reviewed
Hiroshi Yamaguchi,Takashi Fujimoto,Shinobu Nakamura,Koichiro Ohmura,Tsuneyo Mimori,Fumihiko Matsuda,Shigekazu Nagata
EUROPEAN JOURNAL OF IMMUNOLOGY 2010.6
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Milk fat globule EGF factor 8 in the serum of human patients of systemic lupus erythematosus Invited Reviewed
Hiroshi Yamaguchi,Junichi Takagi,Takako Miyamae,Shumpei Yokota,Takashi Fujimoto,Shinobu Nakamura,Shiro Ohshima,Tetsuji Naka,Shigekazu Nagata
JOURNAL OF LEUKOCYTE BIOLOGY 2008.2
Books 1
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MFG-E8およびTim4を介したアポトーシス細胞の認識・貪食機構とその破綻 実験医学増刊 細胞死研究総集編
山口裕嗣, 長田重一（ Role： Joint author）
2010.4
Presentations 5
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Dorsal Medial Hypothalamus GABA Neurons that Regulate Torpor –Potential Application to Space Missions. Invited
Hiroshi Yamaguchi, Luis de Lecea
NASA Ames space torpor workshop 2018
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SLE患者血中におけるMFG-E8
山口裕嗣, 長田重一
第17回日本アポトーシス研究会学術集会 2008
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Release by apoptotic cells of a factor(s) that regulates the gene expression in macrophages.
Hiroshi Yamaguchi, Shigekazu Nagata
13th International TNF Conference 2011
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Immunosuppression via adenosine receptor activation by AMP released from apoptotic cells.
Hiroshi Yamaguchi, Shigekazu Nagata
Keystone Symposia on Molecular Cell Biology of Macrophages in Human Diseases 2014
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Awakening actions of norepinephrine probed with cell type-specific CRISPR gene editing in locus coeruleus.
Hiroshi Yamaguchi, Luis de Lecea
SfN’s 47th annual meeting 2017