論文 - 愛場 雄一郎
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Transfection of PNA-NLS Conjugates into Human Cells Using Partially Complementary Oligonucleotides 査読有り
Aiba Yuichiro, Ohyama Junpei, Komiyama Makoto
CHEMISTRY LETTERS 44 巻 ( 11 ) 頁: 1547 - 1549 2015年11月
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Promotion of double-duplex invasion of peptide nucleic acids through conjugation with nuclear localization signal peptide. 査読有り
Aiba Y, Honda Y, Komiyama M
Chemistry (Weinheim an der Bergstrasse, Germany) 21 巻 ( 10 ) 頁: 4021 - 6 2015年3月
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Exploring the effect of sequence length and composition on allele-selective inhibition of human huntingtin expression by single-stranded silencing RNAs. 査読有り
Hu J, Liu J, Yu D, Aiba Y, Lee S, Pendergraff H, Boubaker J, Artates JW, Lagier-Tourenne C, Lima WF, Swayze EE, Prakash TP, Corey DR
Nucleic acid therapeutics 24 巻 ( 3 ) 頁: 199 - 209 2014年6月
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Allele-selective inhibition of expression of huntingtin and ataxin-3 by RNA duplexes containing unlocked nucleic acid substitutions. 査読有り
Aiba Y, Hu J, Liu J, Xiang Q, Martinez C, Corey DR
Biochemistry 52 巻 ( 51 ) 頁: 9329 - 38 2013年12月
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ss-siRNAs allele selectively inhibit ataxin-3 expression: multiple mechanisms for an alternative gene silencing strategy 査読有り
Liu Jing, Yu Dongbo, Aiba Yuichiro, Pendergraff Hannah, Swayze Eric E., Lima Walt F., Hu Jiaxin, Prakash Thazha P., Corey David R.
NUCLEIC ACIDS RESEARCH 41 巻 ( 20 ) 頁: 9570 - 9583 2013年11月
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Site-selective Scission of Double-stranded DNA by Combining a Triplex-forming bis-PNA and Ce(IV)/EDTA 査読有り
Aiba Yuichiro, Yasuda Kohei, Komiyama Makoto
CHEMISTRY LETTERS 42 巻 ( 10 ) 頁: 1300 - 1302 2013年10月
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PNA-NLS conjugates as single-molecular activators of target sites in double-stranded DNA for site-selective scission 査読有り 国際共著
Aiba Yuichiro, Hamano Yuya, Kameshima Wataru, Araki Yasuyuki, Wada Takehiko, Accetta Alessandro, Sforza Stefano, Corradini Roberto, Marchelli Rosangela, Komiyama Makoto
ORGANIC & BIOMOLECULAR CHEMISTRY 11 巻 ( 32 ) 頁: 5233 - 5238 2013年8月
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Clear-cut observation of PNA invasion using nanomechanical DNA origami devices. 査読有り
Yamazaki T, Aiba Y, Yasuda K, Sakai Y, Yamanaka Y, Kuzuya A, Ohya Y, Komiyama M
Chemical communications (Cambridge, England) 48 巻 ( 92 ) 頁: 11361 - 3 2012年11月
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Artificial site-selective DNA cutters to manipulate single-stranded DNA 査読有り
Aiba Yuichiro, Komiyama Makoto
POLYMER JOURNAL 44 巻 ( 9 ) 頁: 929 - 938 2012年9月
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Introduction of multiphosphonate ligand to peptide nucleic acid for metal ion conjugation. 査読有り
Aiba Y, Honda Y, Han Y, Komiyama M
Artificial DNA, PNA & XNA 3 巻 ( 2 ) 頁: 73 - 9 2012年4月
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Nanomechanical DNA origami devices as versatile molecular sensors 査読有り
Kuzuya Akinori, Yamazaki Takahiro, Yasuda Kohei, Sakai Yusuke, Yamanaka Yusei, Xu Yan, Aiba Yuichiro, Ohya Yuichi, Komiyama Makoto
IEEE Int. Conf. Nano/Micro Eng. Mol. Syst., 7th 頁: 318-321 2012年
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Artificial DNA cutters for DNA manipulation and genome engineering. 査読有り
Aiba Y, Sumaoka J, Komiyama M
Chemical Society reviews 40 巻 ( 12 ) 頁: 5657 - 68 2011年12月
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Manipulation of single-stranded DNA by using an artificial site-selective DNA cutter composed of cerium(IV)/EDTA and phosphonate-oligonucleotide conjugates. 査読有り 国際誌
Aiba Y, Lönnberg T, Komiyama M
Chemistry, an Asian journal 6 巻 ( 9 ) 頁: 2407 - 11 2011年9月
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Chemical and enzymatic stability of amino acid derived phosphoramidates of antiviral nucleoside 5'-monophosphates bearing a biodegradable protecting group. 査読有り
Leisvuori A, Aiba Y, Lönnberg T, Poijärvi-Virta P, Blatt L, Beigelman L, Lönnberg H
Organic & biomolecular chemistry 8 巻 ( 9 ) 頁: 2131 - 41 2010年5月
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Oxidation of an oligonucleotide-bound Ce(III)/multiphosphonate complex for site-selective DNA scission. 査読有り
Lönnberg T, Aiba Y, Hamano Y, Miyajima Y, Sumaoka J, Komiyama M
Chemistry (Weinheim an der Bergstrasse, Germany) 16 巻 ( 3 ) 頁: 855 - 9 2010年1月
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Introduction of disulfide bond to the main chain of PNA to switch its hybridization and invasion activity. 査読有り
Aiba Y, Komiyama M
Organic & biomolecular chemistry 7 巻 ( 24 ) 頁: 5078 - 83 2009年12月
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Handy and prompt DNA separation using PNA with internal disulfide bond. 査読有り 国際誌
Aiba Y, Komiyama M
Nucleic acids symposium series (2004) ( 53 ) 頁: 175 - 6 2009年
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Introduction of linkers into PNA for versatile applications. 査読有り 国際誌
Aiba Y, Komiyama M
Nucleic acids symposium series (2004) ( 52 ) 頁: 143 - 4 2008年
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Artificial restriction DNA cutter for site-selective scission of double-stranded DNA with tunable scission site and specificity. 査読有り 国際誌
Komiyama M, Aiba Y, Yamamoto Y, Sumaoka J
Nature protocols 3 巻 ( 4 ) 頁: 655 - 62 2008年
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Activation of double-stranded DNA by one pcPNA strand for its site-selective scission with Ce-IV/EDTA 査読有り
Aiba Yuichiro, Yamamoto Yoji, Komiyama Makoto
CHEMISTRY LETTERS 36 巻 ( 6 ) 頁: 780 - 781 2007年6月