Fred Hutchinson Cancer Research Center, visiting fellow

2008年9月 - 2011年8月

名古屋大学大学院医学系研究科　COE研究員

2006年6月 - 2008年3月

名古屋第一赤十字病院　血液内科

1999年4月 - 2003年3月

名古屋第一赤十字病院　嘱託研修医

1997年4月 - 1999年3月

Impact of center volume on acute graft versus host disease in allogeneic stem cell transplant recipients

Shimomura, Y; Terakura, S; Matsuo, K; Ito, Y; Ichinohe, T; Hashii, Y; Goto, H; Kato, K; Kawamura, K; Onizuka, M; Ishimaru, F; Takahashi, Y; Yanagisawa, A; Ohbiki, M; Tabuchi, K; Atsuta, Y; Fukuda, T; Kanda, J; Murata, M

INTERNATIONAL JOURNAL OF HEMATOLOGY     2025年5月

Development and optimization of Eva1 (MPZL2) targeting chimeric antigen receptor T cells. Open Access

Osaki M, Terakura S, Hirano S, Iwasa T, Hatanaka KC, Hatanaka Y, Sunagawa M, Kokuryo T, Adachi Y, Takeuchi Y, Hanajiri R, Sakanaka C, Murata M, Ebata T, Kiyoi H

Journal for immunotherapy of cancer   13 巻 ( 5 )   2025年5月

Impact of graft-versus-host disease on outcomes of cord blood transplantation according to HLA disparity and its prophylaxis type Open Access

Yokoyama, H; Fuji, S; Murata, M; Hirayama, M; Wake, A; Uchida, N; Tanaka, M; Onizuka, M; Takahashi, S; Doki, N; Maruyama, Y; Ishiwata, K; Uehara, Y; Nishida, T; Sawa, M; Kawakita, T; Eto, T; Ishimaru, F; Kato, K; Ichinohe, T; Atsuta, Y; Terakura, S; Morishima, S

ANNALS OF HEMATOLOGY   104 巻 ( 5 ) 頁： 2905 - 2913   2025年5月

Post-transplant TKIs for Ph plus ALL: practices to date and clinical significance

Nishiwaki, S; Terakura, S; Morishita, T; Goto, T; Inagaki, Y; Miyao, K; Fukushima, N; Hirano, D; Tange, N; Kurahashi, S; Kuwatsuka, Y; Kasai, M; Iida, H; Ozeki, K; Sawa, M; Nishida, T; Kiyoi, H

INTERNATIONAL JOURNAL OF HEMATOLOGY   121 巻 ( 4 ) 頁： 494 - 503   2025年4月

Association between early anti-cytomegalovirus therapy and the incidence of chronic graft-versus-host disease

Miyao, K; Murata, M; Nishida, T; Ozawa, Y; Uchida, N; Fukuda, T; Doki, N; Eto, T; Kawakita, T; Mori, Y; Takada, S; Ohigashi, H; Tanaka, M; Kanda, Y; Matsuoka, KI; Ishimaru, F; Atsuta, Y; Kanda, J; Terakura, S

INTERNATIONAL JOURNAL OF HEMATOLOGY   121 巻 ( 1 ) 頁： 110 - 125   2025年1月

Cullin-5 deficiency promotes chimeric antigen receptor T cell effector functions potentially via the modulation of JAK/STAT signaling pathway

Adachi, Y; Terakura, S; Osaki, M; Okuno, Y; Sato, Y; Sagou, K; Takeuchi, Y; Yokota, H; Imai, K; Steinberger, P; Leitner, J; Hanajiri, R; Murata, M; Kiyoi, H

NATURE COMMUNICATIONS   15 巻 ( 1 ) 頁： 10376   2024年12月

Co-stimulation of CD28/CD40 signaling molecule potentiates CAR-T cell efficacy and stemness Open Access

Khopanlert, W; Choochuen, P; Maneechai, K; Jangphattananont, N; Ung, S; Okuno, S; Steinberger, P; Leitner, J; Sangkhathat, S; Viboonjuntra, P; Terakura, S; Julamanee, J

MOLECULAR THERAPY ONCOLOGY   32 巻 ( 3 ) 頁： 200837   2024年9月

Real-World Outcomes of Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation in Japan: Retrospective Analysis of the Transplant Registry Unified fi ed Management Program Registry

Kanda, J; Mitsuyoshi, T; Sakurai, M; Nishimori, H; Murata, M; Uchida, N; Doki, N; Inamoto, Y; Nishida, T; Tanaka, M; Katayama, Y; Eto, T; Matsuoka, K; Yoshihara, S; Sawa, M; Kawakita, T; Jun, GYJ; Kurata, M; Ichinohe, T; Fukuda, T; Teshima, T; Atsuta, Y; Terakura, S

TRANSPLANTATION AND CELLULAR THERAPY   30 巻 ( 9 ) 頁： 907e1 - 907e16   2024年9月

Associations between acute and chronic graft-versus-host disease

Tamaki, M; Akahoshi, Y; Inamoto, Y; Morita, K; Uchida, N; Doki, N; Tanaka, M; Nishida, T; Ohigashi, H; Nakamae, H; Onizuka, M; Katayama, Y; Matsuoka, KI; Sawa, M; Ishimaru, F; Kanda, Y; Fukuda, T; Atsuta, Y; Terakura, S; Kanda, J

BLOOD ADVANCES   8 巻 ( 16 ) 頁： 4250 - 4261   2024年8月

Long-Term Outcome of Eltrombopag With First-Line Immunosuppressive Therapy for Newly Diagnosed Severe Aplastic Anemia Open Access

Yokota, H; Miyao, K; Sawa, M; Terakura, S; Kurahashi, S; Ikoma, Y; Imahashi, N; Morishita, T; Okamoto, A; Kajiguchi, T; Ono, T; Narita, T; Kanemura, N; Ozeki, K; Kojima, Y; Naito, K; Uchino, K; Tomita, A; Iida, H; Imoto, N; Kasahara, S; Inagaki, Y; Nishida, T; Murata, M

JOURNAL OF HEMATOLOGY   13 巻 ( 4 ) 頁： 142 - 149   2024年8月

Initiating-clone analysis in patients with acute myeloid leukemia secondary to essential thrombocythemia

Ushijima, Y; Naruse, S; Ishikawa, Y; Kawashima, N; Sanada, M; Nakashima, M; Kim, JH; Terakura, S; Kihara, R; Watamoto, K; Nishiyama, T; Kitamura, K; Matsushita, T; Kiyoi, H

SCIENTIFIC REPORTS   14 巻 ( 1 ) 頁： 15906   2024年7月

Dual CAR-T Cells Targeting CD19 and CD37 Are Effective in Target Antigen Loss B-cell Tumor Models

Imai, K; Takeuchi, Y; Terakura, S; Okuno, S; Adachi, Y; Osaki, M; Umemura, K; Hanajiri, R; Shimada, K; Murata, M; Kiyoi, H

MOLECULAR CANCER THERAPEUTICS   23 巻 ( 3 ) 頁： 381 - 393   2024年3月

Scoring system for optimal cord blood unit selection for single cord blood transplantation

Watanabe, M; Konuma, T; Imahashi, N; Terakura, S; Seo, S; Morishima, S; Uchida, N; Doki, N; Tanaka, M; Nishida, T; Kawakita, T; Eto, T; Takahashi, S; Sawa, M; Uehara, Y; Kim, SW; Ishimaru, F; Ichinohe, T; Fukuda, T; Atsuta, Y; Kanda, J

CYTOTHERAPY   26 巻 ( 3 ) 頁： 286 - 298   2024年3月

Impact of Center Volume on Chronic Graft Versus Host Disease in Patients With Allogeneic Stem Cell Transplantation Open Access

Shimomura, Y; Kitamura, T; Murata, M; Matsuo, K; Ito, Y; Ichinohe, T; Hashii, Y; Goto, H; Kato, K; Ishimaru, F; Sato, A; Onizuka, M; Yanagisawa, A; Ohbiki, M; Tabuchi, K; Atsuta, Y; Fukuda, T; Kanda, J; Terakura, S

TRANSPLANTATION AND CELLULAR THERAPY   30 巻 ( 3 ) 頁： 326.e1 - 326.e14   2024年3月

Superior in vivo efficacy of Eva1 targeting CAR-T cell therapy and harnessing by CUL5 knock down

Iwasa, T; Terakura, S; Osaki, M; Hirano, S; Adachi, Y; Kokuryo, T; Sunagawa, M; Hanajiri, R; Kiyoi, H

CANCER SCIENCE   115 巻   頁： 1878 - 1878   2024年3月

Current Status of CD19CAR-T Therapy and Attempts to Improve Therapeutic Effectiveness by Enhancing Effector Functions

Terakura, S

CANCER SCIENCE   115 巻   頁： 807 - 807   2024年3月

Effect of graft-versus-host disease on outcomes of HLA-haploidentical peripheral blood transplantation using post-transplant cyclophophamide

Shimomura, Y; Komukai, S; Kitamura, T; Sobue, T; Akahoshi, Y; Kanda, J; Ohigashi, H; Nakamae, H; Hiramoto, N; Nagafuji, K; Tanaka, T; Eto, T; Ota, S; Maruyama, Y; Akasaka, T; Matsuoka, KI; Mori, Y; Fukuda, T; Atsuta, Y; Terakura, S

BONE MARROW TRANSPLANTATION   59 巻 ( 1 ) 頁： 66 - 75   2024年1月

Analysis of Metabolic Mechanism of CD19CAR-T with CD79A/CD40 Co-Stimulatory Domain Based on Comparison with Established CAR-Ts

Takeuchi, Y; Terakura, S; Hirano, S; Yokota, H; Kuwano, S; Osaki, M; Adachi, Y; Imai, K; Julamanee, J; Hanajiri, R; Murata, M; Kiyoi, H

BLOOD   142 巻   2023年11月

REAL-WORLD OUTCOMES OF GRAFT-VERSUS-HOST DISEASE AFTER ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN JAPAN: RETROSPECTIVE ANALYSIS OF TRANSPLANT REGISTRY UNIFIED MANAGEMENT PROGRAM REGISTRY

Kanda, J; Mitsuyoshi, T; Sakurai, M; Nishimori, H; Murata, M; Uchida, N; Doki, N; Inamoto, Y; Ozawa, Y; Tanaka, M; Katayama, Y; Eto, T; Matsuoka, K; Jun, G; Kurata, M; Ichinohe, T; Fukuda, T; Teshima, T; Atsuta, Y; Terakura, S

BONE MARROW TRANSPLANTATION   58 巻 ( SUPP1 ) 頁： 307 - 308   2023年11月

Antibody response after third dose of COVID-19 mRNA vaccination in allogeneic hematopoietic stem cell transplant recipients is comparable to that in healthy counterparts

Takagi, E; Terakura, S; Fujigaki, H; Okamoto, A; Miyao, K; Sawa, M; Morishita, T; Goto, T; Ozawa, Y; Nishida, T; Fukushima, N; Ozeki, K; Hanajiri, R; Saito, K; Murata, M; Tomita, A; Kiyoi, H

INTERNATIONAL JOURNAL OF HEMATOLOGY   118 巻 ( 4 ) 頁： 462 - 471   2023年10月

A convolutional neural network-based model that predicts acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation (vol 3, 67, 2023)

Jo, T; Arai, Y; Kanda, J; Kondo, T; Ikegame, K; Uchida, N; Doki, N; Fukuda, T; Ozawa, Y; Tanaka, M; Ara, T; Kuriyama, T; Katayama, Y; Kawakita, T; Kanda, Y; Onizuka, M; Ichinohe, T; Atsuta, Y; Terakura, S

COMMUNICATIONS MEDICINE   3 巻 ( 1 ) 頁： 89   2023年6月

Different effects of thymoglobulin on acute leukemia with pre-transplant residual blasts in HLA mismatch transplantation

Wakamatsu, M; Murata, M; Kanda, J; Fukushima, K; Fukuda, T; Najima, Y; Katayama, Y; Ozawa, Y; Tanaka, M; Kanda, Y; Eto, T; Takada, S; Kako, S; Uchida, N; Kawakita, T; Yoshiko, H; Ichinohe, T; Atsuta, Y; Terakura, S

INTERNATIONAL JOURNAL OF HEMATOLOGY   117 巻 ( 6 ) 頁： 889 - 899   2023年6月

A convolutional neural network-based model that predicts acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation

Jo, T; Arai, Y; Kanda, J; Kondo, T; Ikegame, K; Uchida, N; Doki, N; Fukuda, T; Ozawa, Y; Tanaka, M; Ara, T; Kuriyama, T; Katayama, Y; Kawakita, T; Kanda, Y; Onizuka, M; Ichinohe, T; Atsuta, Y; Terakura, S

COMMUNICATIONS MEDICINE   3 巻 ( 1 ) 頁： 67   2023年5月

Novel CAR-T cell therapy for solid tumors targeting epithelial V-like antigen 1

Osaki, M; Terakura, S; Sunagawa, M; Kokuryo, T; Nishida, T; Murata, M; Kiyoi, H

CANCER SCIENCE   114 巻   頁： 1415 - 1415   2023年2月

Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells

Ueda, T; Shiina, S; Iriguchi, S; Terakura, S; Kawai, Y; Kabai, R; Sakamoto, S; Watanabe, A; Ohara, K; Wang, B; Xu, HG; Minagawa, A; Hotta, A; Woltjen, K; Uemura, Y; Kodama, Y; Seno, H; Nakatsura, T; Tamada, K; Kaneko, S

NATURE BIOMEDICAL ENGINEERING   7 巻 ( 1 ) 頁： 24 - +   2023年1月

[Cellular kinetics and outcome of tisagenlecleucel for diffuse large B-cell lymphoma].

Hanajiri R, Furukawa K, Nakashima M, Ushijima Y, Shimada K, Ishikawa Y, Terakura S, Murata M, Kiyoi H

[Rinsho ketsueki] The Japanese journal of clinical hematology   64 巻 ( 3 ) 頁： 167 - 174   2023年

[Selection strategy for graft source in 2023].

Terakura S

[Rinsho ketsueki] The Japanese journal of clinical hematology   64 巻 ( 9 ) 頁： 1152 - 1157   2023年

[Challenges and prospects for CAR-T therapy].

Terakura S

[Rinsho ketsueki] The Japanese journal of clinical hematology   64 巻 ( 11 ) 頁： 1470 - 1476   2023年

Enrichment of T-cell proliferation and memory gene signatures of CD79A/CD40 costimulatory domain potentiates CD19CAR-T cell functions Open Access

Ung, S; Choochuen, P; Khopanlert, W; Maneechai, K; Sangkhathat, S; Terakura, S; Julamanee, J

FRONTIERS IN IMMUNOLOGY   13 巻   頁： 1064339   2022年11月

Co-Stimulation of CD28/CD40 Signaling Molecule Potentiates CD19CAR-T Cell Functions and Stemness

Khopanlert, W; Choochuen, P; Jangphattananont, N; Maneechai, K; Ung, S; Sangkhathat, S; Viboonjuntra, P; Terakura, S; Julamanee, J

BLOOD   140 巻   頁： 7364 - 7365   2022年11月

Downregulation of HLA class II is associated with relapse after allogeneic stem cell transplantation and alters recognition by antigen-specific T cells

Adachi, Y; Sakai, T; Terakura, S; Shiina, T; Suzuki, S; Hamana, H; Kishi, H; Sasazuki, T; Arase, H; Hanajiri, R; Goto, T; Nishida, T; Murata, M; Kiyoi, H

INTERNATIONAL JOURNAL OF HEMATOLOGY   115 巻 ( 3 ) 頁： 371 - 381   2022年3月

Antithymocyte Globulin Potentially Could Overcome an Adverse Effect of Acute Graft-versus-Host Disease in Matched-Related Peripheral Blood Stem Cell Transplantation

Miyao, K; Kuwatsuka, Y; Murata, M; Nagafuji, K; Teshima, T; Takeuchi, Y; Shiratori, S; Najima, Y; Uchida, N; Tanaka, M; Sawa, M; Ota, S; Fukuda, T; Ozawa, Y; Kako, S; Kawakita, T; Ara, T; Tanaka, J; Kanda, Y; Atsuta, Y; Kanda, J; Terakura, S

TRANSPLANTATION AND CELLULAR THERAPY   28 巻 ( 3 ) 頁： 153.e1 - 153.e11   2022年3月

Impact of donor types on reduced-intensity conditioning allogeneic stem cell transplant for mature lymphoid malignancies

Imahashi, N; Terakura, S; Kondo, E; Kato, K; Kim, SW; Shinohara, A; Watanabe, M; Fukuda, T; Uchida, N; Kobayashi, H; Ishikawa, J; Kataoka, K; Shiratori, S; Ikeda, T; Matsuoka, KI; Yoshida, S; Kondo, T; Kimura, T; Onizuka, M; Ichinohe, T; Atsuta, Y; Kanda, J

BONE MARROW TRANSPLANTATION   57 巻 ( 2 ) 頁： 243 - 251   2022年2月

Cytomegalovirus gastroenteritis in patients with acute graft-versus-host disease.

Akahoshi Y, Kimura SI, Tada Y, Matsukawa T, Tamaki M, Doki N, Uchida N, Tanaka M, Nakamae H, Kuriyama T, Matsuoka KI, Ikeda T, Kimura T, Fukuda T, Kanda Y, Atsuta Y, Murata M, Terakura S, Nakasone H

Blood advances   6 巻 ( 2 ) 頁： 574 - 584   2022年1月

Cytomegalovirus gastroenteritis in patients with acute graft-versus- host disease

Akahoshi Yu, Kimura Shun-Ichi, Tada Yuma, Matsukawa Toshihiro, Tamaki Masaharu, Doki Noriko, Uchida Naoyuki, Tanaka Masatsugu, Nakamae Hirohisa, Kuriyama Takuro, Matsuoka Ken-Ichi, Ikeda Takashi, Kimura Takafumi, Fukuda Takahiro, Kanda Yoshinobu, Atsuta Yoshiko, Murata Makoto, Terakura Seitaro, Nakasone Hideki

BLOOD ADVANCES   6 巻 ( 2 ) 頁： 574 - 584   2022年1月

Altered effect of killer immunoglobulin-like receptor-ligand mismatch by graft versus host disease prophylaxis in cord blood transplantation

Yokoyama, H; Hirayama, M; Takahashi, Y; Uchida, N; Tanaka, M; Onizuka, M; Ozawa, Y; Onai, D; Katsuoka, Y; Wake, A; Sawa, M; Kobayashi, H; Maruyama, Y; Ozeki, K; Kimura, T; Kanda, J; Fukuda, T; Atsuta, Y; Terakura, S; Morishima, S

BONE MARROW TRANSPLANTATION   56 巻 ( 12 ) 頁： 3059 - 3067   2021年12月

Impact of HLA disparity on the risk of overall mortality in patients with grade II-IV acute GVHD on behalf of the HLA Working Group of Japan Society for Hematopoietic Cell Transplantation

Fuji, S; Hakoda, A; Kanda, J; Murata, M; Terakura, S; Inamoto, Y; Uchida, N; Toya, T; Eto, T; Nakamae, H; Ikegame, K; Tanaka, M; Kawakita, T; Kondo, T; Miyamoto, T; Fukuda, T; Ichinohe, T; Kimura, T; Atsuta, Y; Shintani, A; Morishima, S

BONE MARROW TRANSPLANTATION   56 巻 ( 12 ) 頁： 2990 - 2996   2021年12月

Cytomegalovirus Gastroenteritis in Patients with Acute Graft-Versus-Host Disease

Akahoshi Yu, Kimura Shun-ichi, Tada Yuma, Matsukawa Toshihiro, Tamaki Masaharu, Doki Noriko, Uchida Naoyuki, Tanaka Masatsugu, Nakamae Hirohisa, Kuriyama Takuro, Matsuoka Ken-ichi, Ikeda Takashi, Kimura Takafumi, Fukuda Takahiro, Kanda Yoshinobu, Atsuta Yoshiko, Murata Makoto, Terakura Seitaro, Nakasone Hideki

BLOOD   138 巻   2021年11月

Off-the-shelf bone marrow-derived mesenchymal stem cell treatment for acute graft-versus-host disease: real-world evidence

Murata, M; Terakura, S; Wake, A; Miyao, K; Ikegame, K; Uchida, N; Kataoka, K; Miyamoto, T; Onizuka, M; Eto, T; Doki, N; Ota, S; Sato, M; Hashii, Y; Ichinohe, T; Fukuda, T; Atsuta, Y; Okamoto, S; Teshima, T

BONE MARROW TRANSPLANTATION   56 巻 ( 10 ) 頁： 2355 - 2366   2021年10月

Composite CD79A/CD40 co-stimulatory endodomain enhances CD19CAR-T cell proliferation and survival

Julamanee, J; Terakura, S; Umemura, K; Adachi, Y; Miyao, K; Okuno, S; Takagi, E; Sakai, T; Koyama, D; Goto, T; Hanajiri, R; Hudecek, M; Steinberger, P; Leitner, J; Nishida, T; Murata, M; Kiyoi, H

MOLECULAR THERAPY   29 巻 ( 9 ) 頁： 2677 - 2690   2021年9月

Low-dose antithymocyte globulin inhibits chronic graft-versus-host disease in peripheral blood stem cell transplantation from unrelated donors

Shiratori, S; Sugita, J; Fuji, S; Aoki, J; Sawa, M; Ozawa, Y; Hashimoto, D; Matsuoka, KI; Imada, K; Doki, N; Ashida, T; Ueda, Y; Tanaka, M; Sawayama, Y; Ichinohe, T; Terakura, S; Morishima, S; Atsuta, Y; Fukuda, T; Teshima, T

BONE MARROW TRANSPLANTATION   56 巻 ( 9 ) 頁： 2231 - 2240   2021年9月

Effect of Cytomegalovirus Reactivation With or Without Acute Graft-Versus-Host Disease on the Risk of Nonrelapse Mortality

Akahoshi, Y; Kimura, SI; Inamoto, Y; Seo, S; Muranushi, H; Shimizu, H; Ozawa, Y; Tanaka, M; Uchida, N; Kanda, Y; Katayama, Y; Shiratori, S; Ota, S; Matsuoka, K; Onizuka, M; Fukuda, T; Atsuta, Y; Murata, M; Terakura, S; Nakasone, H

CLINICAL INFECTIOUS DISEASES   73 巻 ( 3 ) 頁： E620 - E628   2021年8月

Spacer Length Modification Facilitates Discrimination between Normal and Neoplastic Cells and Provides Clinically Relevant CD37 CAR T Cells

Okuno, S; Adachi, Y; Terakura, S; Julamanee, J; Sakai, T; Umemura, K; Miyao, K; Goto, T; Murase, A; Shimada, K; Nishida, T; Murata, M; Kiyoi, H

JOURNAL OF IMMUNOLOGY   206 巻 ( 12 ) 頁： 2862 - 2874   2021年6月

Effect of methotrexate dose in graft-versus-host disease prophylaxis after single-unit cord blood transplantation in adult acute myeloid leukemia

Terakura, S; Kuwatsuka, Y; Sugita, J; Takahashi, S; Ozawa, Y; Ozeki, K; Yoshioka, S; Nakamae, H; Kawakita, T; Sawa, M; Morishige, S; Najima, Y; Katsuoka, Y; Sakaida, E; Kouzai, Y; Kimura, T; Ichinohe, T; Fukuda, T; Atsuta, Y; Murata, M; Teshima, T

INTERNATIONAL JOURNAL OF HEMATOLOGY   113 巻 ( 6 ) 頁： 840 - 850   2021年6月

Phase I clinical trial of intra-bone marrow cotransplantation of mesenchymal stem cells in cord blood transplantation

Goto, T; Murata, M; Nishida, T; Terakura, S; Kamoshita, S; Ishikawa, Y; Ushijima, Y; Adachi, Y; Suzuki, S; Kato, K; Hirakawa, A; Nishiwaki, S; Nishio, N; Takahashi, Y; Kodera, Y; Matsushita, T; Kiyoi, H

STEM CELLS TRANSLATIONAL MEDICINE   10 巻 ( 4 ) 頁： 542 - 553   2021年4月

Comparison of Transplantation Outcomes after Foscarnet and Ganciclovir Administration as First-Line Anti-Cytomegalovirus Preemptive Therapy

Miyao, K; Terakura, S; Ozawa, Y; Sawa, M; Kohno, A; Kasahara, S; Iida, H; Ino, K; Kusumoto, S; Kasai, M; Takami, A; Kurahashi, S; Kajiguchi, T; Morishita, T; Nishida, T; Murata, M

TRANSPLANTATION AND CELLULAR THERAPY   27 巻 ( 4 ) 頁： 342.e1 - 342.e10   2021年4月

Single Cord Blood Transplantation Versus Unmanipulated Haploidentical Transplantation for Adults with Acute Myeloid Leukemia in Complete Remission

Konuma, T; Kanda, J; Yamasaki, S; Harada, K; Shimomura, Y; Terakura, S; Mizuno, S; Uchida, N; Tanaka, M; Doki, N; Ozawa, Y; Nakamae, H; Sawa, M; Matsuoka, KI; Morishige, S; Maruyama, Y; Ikegame, K; Kimura, T; Kanda, Y; Ichinohe, T; Atsuta, Y; Yanada, M

TRANSPLANTATION AND CELLULAR THERAPY   27 巻 ( 4 ) 頁： 334.e1 - 334.e11   2021年4月

A multicenter phase II study of intrabone single-unit cord blood transplantation without antithymocyte globulin

Nishida, T; Kobayashi, T; Sawa, M; Masuda, S; Shibasaki, Y; Goto, T; Fukuhara, N; Fujii, N; Ikegame, K; Sugita, J; Ikeda, T; Kuwatsuka, Y; Suzuki, R; Najima, Y; Doki, N; Kato, T; Inagaki, Y; Utsu, Y; Aotsuka, N; Masuko, M; Terakura, S; Onishi, Y; Maeda, Y; Okada, M; Teshima, T; Murata, M

ANNALS OF HEMATOLOGY   100 巻 ( 3 ) 頁： 743 - 752   2021年3月

Comparison of immunosuppressant regimens in salvage cord blood transplantation for graft failure after allogeneic hematopoietic stem cell transplantation

Harada, K; Fuji, S; Seo, S; Uchida, N; Kawakita, T; Yano, S; Ozawa, Y; Yoshioka, S; Onishi, Y; Noguchi, Y; Onizuka, M; Matsuhashi, Y; Kimura, T; Ichinohe, T; Atsuta, Y; Terakura, S; Nakasone, H

BONE MARROW TRANSPLANTATION   56 巻 ( 2 ) 頁： 400 - 410   2021年2月

Comparison of reduced-intensity/toxicity conditioning regimens for umbilical cord blood transplantation for lymphoid malignancies

Imahashi, N; Terakura, S; Kondo, E; Kako, S; Uchida, N; Kobayashi, H; Inamoto, Y; Sakai, H; Tanaka, M; Ishikawa, J; Kozai, Y; Matsuoka, K; Kimura, T; Fukuda, T; Atsuta, Y; Kanda, J

BONE MARROW TRANSPLANTATION   55 巻 ( 11 ) 頁： 2098 - 2108   2020年11月

Safety and efficacy of anti-programmed cell death-1 monoclonal antibodies before and after allogeneic hematopoietic cell transplantation for relapsed or refractory Hodgkin lymphoma: a multicenter retrospective study

Ito, A; Kim, SW; Matsuoka, KI; Kawakita, T; Tanaka, T; Inamoto, Y; Toubai, T; Fujiwara, SI; Fukaya, M; Kondo, T; Sugita, J; Nara, M; Katsuoka, Y; Imai, Y; Nakazawa, H; Kawashima, I; Sakai, R; Ishii, A; Onizuka, M; Takemura, T; Terakura, S; Iida, H; Nakamae, M; Higuchi, K; Tamura, S; Yoshioka, S; Togitani, K; Kawano, N; Suzuki, R; Suzumiya, J; Izutsu, K; Teshima, T; Fukuda, T

INTERNATIONAL JOURNAL OF HEMATOLOGY   112 巻 ( 5 ) 頁： 674 - 689   2020年11月

Artificial T Cell Adaptor Molecule-Transduced TCR-T Cells Demonstrated Improved Proliferation Only When Transduced in a Higher Intensity

Sakai, T; Terakura, S; Miyao, K; Okuno, S; Adachi, Y; Umemura, K; Julamanee, J; Watanabe, K; Hamana, H; Kishi, H; Leitner, J; Steinberger, P; Nishida, T; Murata, M; Kiyoi, H

MOLECULAR THERAPY-ONCOLYTICS   18 巻   頁： 613 - 622   2020年9月

Updated Comparison of 7/8 HLA Allele-Matched Unrelated Bone Marrow Transplantation and Single-Unit Umbilical Cord Blood Transplantation as Alternative Donors in Adults with Acute Leukemia.

Miyao K, Terakura S, Kimura F, Konuma T, Miyamura K, Yanada M, Kako S, Morhishima S, Uchida N, Toya T, Ozawa Y, Fukuda T, Tanaka M, Sawa M, Takada S, Yoshida S, Kimura T, Ichinohe T, Atsuta Y, Kanda J, Donor/Source Working Group of the Japan Society for Hematopoietic Cell Transplantation.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation     2020年8月

Staurosporine and venetoclax induce the caspase-dependent proteolysis of MEF2D-fusion proteins and apoptosis in <i>MEF2D</i>-fusion (+) ALL cells

Tange, N; Hayakawa, F; Yasuda, T; Odaira, K; Yamamoto, H; Hirano, D; Sakai, T; Terakura, S; Tsuzuki, S; Kiyoi, H

BIOMEDICINE & PHARMACOTHERAPY   128 巻   頁： 110330   2020年8月

Prospective evaluation of alternative donor from unrelated donor and cord blood in adult acute leukemia and myelodysplastic syndrome.

Terakura S, Nishida T, Sawa M, Kato T, Miyao K, Ozawa Y, Goto T, Kohno A, Ozeki K, Onishi Y, Fukuhara N, Fujii N, Yokoyama H, Kasai M, Iida H, Kanemura N, Endo T, Ago H, Onizuka M, Iyama S, Nawa Y, Nakamae M, Nagata Y, Kurahashi S, Tomiya Y, Yanagisawa A, Suzuki R, Kuwatsuka Y, Atsuta Y, Miyamura K, Murata M, Nagoya Blood and Marrow Transplantation Group.

Bone marrow transplantation     2020年3月

Analysis of glutathione <i>S</i>-transferase and cytochrome P450 gene polymorphism in recipients of dose-adjusted busulfan-cyclophosphamide conditioning

Terakura, S; Onizuka, M; Fukumoto, M; Kuwatsuka, Y; Kohno, A; Ozawa, Y; Miyamura, K; Inagaki, Y; Sawa, M; Atsuta, Y; Suzuki, R; Naoe, T; Morishita, Y; Murata, M

INTERNATIONAL JOURNAL OF HEMATOLOGY   111 巻 ( 1 ) 頁： 84 - 92   2020年1月

Prospective Phase 2 Study of Umbilical Cord Blood Transplantation in Adult Acute Leukemia and Myelodysplastic Syndrome

Terakura, S; Nishida, T; Sawa, M; Kato, T; Miyao, K; Ozawa, Y; Kohno, A; Onishi, Y; Fukuhara, N; Kasai, M; Fujii, N; Yokoyama, H; Iida, H; Kanemura, N; Fujieda, A; Ago, H; Tsutsumi, Y; Nakamura, F; Yago, K; Moriuchi, Y; Ota, S; Ohashi, H; Yanagisawa, A; Suzuki, R; Kuwatsuka, Y; Atsuta, Y; Miyamura, K; Murata, M

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION   26 巻 ( 1 ) 頁： 139 - 144   2020年1月

Donor single nucleotide polymorphism in <i>ACAT1</i> affects the incidence of graft-versus-host disease after bone marrow transplantation

Kamoshita, S; Murata, M; Koyama, D; Julamanee, J; Okuno, S; Takagi, E; Miyao, K; Goto, T; Ozawa, Y; Miyamura, K; Terakura, S; Nishida, T; Kiyoi, H

INTERNATIONAL JOURNAL OF HEMATOLOGY   111 巻 ( 1 ) 頁： 112 - 119   2020年1月

Analysis of glutathione <i>S</i>-transferase and cytochrome P450 gene polymorphism in recipients of dose-adjusted busulfan-cyclophosphamide conditioning (vol 74, pg 238, 2019)

Terakura, S; Onizuka, M; Fukumoto, M; Kuwatsuka, Y; Kohno, A; Ozawa, Y; Miyamura, K; Inagaki, Y; Sawa, M; Atsuta, Y; Suzuki, R; Naoe, T; Morishita, Y; Murata, M

INTERNATIONAL JOURNAL OF HEMATOLOGY   111 巻 ( 1 ) 頁： 159 - 160   2020年1月

Randomised controlled trial of conditioning regimen for cord blood transplantation for adult myeloid malignancies comparing high-dose cytarabine/cyclophosphamide/total body irradiation with versus without G-CSF priming: G-CONCORD study protocol

Terakura, S; Konuma, T; Tanaka, M; Ozawa, Y; Onizuka, M; Nanno, S; Onishi, Y; Aotsuka, N; Kondo, T; Kawakita, T; Kato, J; Kobayashi, T; Nishida, T; Yamaguchi, T; Kuwatsuka, Y; Takahashi, S

BMJ OPEN   10 巻 ( 12 ) 頁： e040467   2020年

Phase I Study of Cord Blood Transplantation with Intra-Bone Marrow Injection of Mesenchymal Stem Cells

Goto Tatsunori, Murata Makoto, Nishida Tetsuya, Terakura Seitaro, Kamoshita Sonoko, Ishikawa Yuichi, Ushijima Yoko, Adachi Yoshiya, Kato Katsuyoshi, Hirakawa Akihiro, Nishiwaki Satoshi, Nishio Nobuhiro, Takahashi Yoshiyuki, Kodera Yoshihisa, Matsushita Tadashi, Kiyoi Hitoshi

BLOOD   134 巻   2019年11月

Prospective Evaluation of Alternative Donor from Unrelated Volunteer Donor and Cord Blood in Adult Acute Leukemia and Myelodysplastic Syndrome: No Difference between Unrelated Donor and Cord Blood

Terakura Seitaro, Nishida Tetsuya, Sawa Masashi, Kato Tomonori, Miyao Kotaro, Ozawa Yukiyasu, Goto Tatsunori, Kohno Akio, Ozeki Kazutaka, Onishi Yasushi, Fukuhara Noriko, Fujii Nobuharu, Yokoyama Hisayuki, Kasai Masanobu, Iida Hiroatsu, Kanemura Nobuhiro, Endo Tomoyuki, Ago Hiroatsu, Onizuka Makoto, Iyama Satoshi, Nawa Yuichiro, Nakamae Mika, Nagata Yasuyuki, Kurahashi Shingo, Tomiya Yasuo, Yanagisawa Atsumi, Suzuki Ritsuro, Kuwatsuka Yachiyo, Atsuta Yoshiko, Miyamura Koichi, Murata Makoto

BLOOD   134 巻   2019年11月

Enhanced effector responses of regenerated CAR-T cells derived from genome edited iPSCs

Ueda Tatsuki, Iriguchi Shoichi, Kawai Yohei, Minagawa Atsutaka, Miyoshi Hiroyuki, Terakura Seitaro, Uemura Yasushi, Woltjen Knut, Kodama Yuzo, Seno Hiroshi, Hitoshi Yasumichi, Nakatsura Tetsuya, Tamada Koji, Kaneko Shin

CANCER RESEARCH   79 巻 ( 13 )   2019年7月

Quantitative Assessment of T Cell Clonotypes in Human Acute Graft-versus-Host Disease Tissues.

Koyama D, Murata M, Hanajiri R, Akashi T, Okuno S, Kamoshita S, Julamanee J, Takagi E, Miyao K, Sakemura R, Goto T, Terakura S, Nishida T, Kiyoi H

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation   25 巻 ( 3 ) 頁： 417 - 423   2019年3月

Impacts of thymoglobulin in patients with acute leukemia in remission undergoing allogeneic HSCT from different donors.

Wakamatsu M, Terakura S, Ohashi K, Fukuda T, Ozawa Y, Kanamori H, Sawa M, Uchida N, Ota S, Matsushita A, Kanda Y, Nakamae H, Ichinohe T, Kato K, Murata M, Atsuta Y, Teshima T, GVHD Working Group of the Japan Society for Hematopoietic Cell Transplantation.

Blood advances   3 巻 ( 2 ) 頁： 105-115   2019年1月

[Successful treatment of pre-engraftment disseminated fusariosis with high-dose liposomal amphotericin B in a cord blood transplant recipient].

Harada Y, Murata M, Matsumoto A, Kato D, Yagi T, Yaguchi T, Yoshikawa T, Takeichi T, Akiyama M, Yamaguchi Y, Koyama D, Terakura S, Nishida T, Kiyoi H

[Rinsho ketsueki] The Japanese journal of clinical hematology   60 巻 ( 12 ) 頁： 1641-1646   2019年

Identification of the novel deletion-type <i>PML-RARA</i> mutation associated with the retinoic acid resistance in acute promyelocytic leukemia

Hattori, H; Ishikawa, Y; Kawashima, N; Akashi, A; Yamaguchi, Y; Harada, Y; Hirano, D; Adachi, Y; Miyao, K; Ushijima, Y; Terakura, S; Nishida, T; Matsushita, T; Kiyoi, H

PLOS ONE   13 巻 ( 10 ) 頁： e0204850   2018年10月

Generation of CAR-iPS-T cells expressing CD8 beta

Ueda Tatsuki, Iriguchi Shoichi, Kawai Yohei, Minagawa Atsutaka, Miyoshi Hiroyuki, Terakura Seitaro, Uemura Yasushi, Woltjen Knut, Kodama Yuzo, Seno Hiroshi, Hitoshi Yasumichi, Nakatsura Tetsuya, Tamada Koji, Kaneko Shin

CANCER RESEARCH   78 巻 ( 13 )   2018年7月

Introduction of Genetically Modified CD3ζ Improves Proliferation and Persistence of Antigen-Specific CTLs

Miyao, K; Terakura, S; Okuno, S; Julamanee, J; Watanabe, K; Hamana, H; Kishi, H; Sakemura, R; Koyama, D; Goto, T; Nishida, T; Murata, M; Kiyoi, H

CANCER IMMUNOLOGY RESEARCH   6 巻 ( 6 ) 頁： 733 - 744   2018年6月

Phase I study of cord blood transplantation with intrabone marrow injection of mesenchymal stem cells: A clinical study protocol

Goto, T; Murata, M; Terakura, S; Nishida, T; Adachi, Y; Ushijima, Y; Shimada, K; Ishikawa, Y; Hayakawa, F; Nishio, N; Nishiwaki, S; Hirakawa, A; Kato, K; Takahashi, Y; Kiyoi, H

MEDICINE   97 巻 ( 17 ) 頁： e0449   2018年4月

High Incidence of Extensive Chronic Gvhd in Patients with the <i>REG3A</i> Rs7588571 Non-GG Genotype

Murata, M; Koyama, D; Hanajiri, R; Okuno, S; Kamoshita, S; Julamanee, J; Takagi, E; Hirano, D; Miyao, K; Sakemura, R; Goto, T; Hayakawa, F; Seto, A; Ozawa, Y; Miyamura, K; Terakura, S; Nishida, T; Kiyoi, H

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION   24 巻 ( 3 ) 頁： S192 - S193   2018年3月

Intrabone single unit cord blood transplantation for hematological malignancies

Murata, M; Maeda, Y; Masuko, M; Fukuhara, N; Nishida, T; Terakura, S; Ishikawa, Y; Tanimoto, M; Shibasaki, Y; Suzuki, R; Kodera, Y; Kiyoi, H; Naoe, T

CANCER SCIENCE   109 巻   頁： 757 - 757   2018年1月

iPSC-based CAR-T therapy targeting for GPC3

Ueda, T; Irigchi, S; Kawai, Y; Minagawa, A; Miyoshi, H; Terakura, S; Uemura, Y; Woltjen, K; Kodama, Y; Tamada, K; Nakatsura, T; Seno, H; Kaneko, S

CANCER SCIENCE   109 巻   頁： 294 - 294   2018年1月

[MonoMAC syndrome patient developing myelodysplastic syndrome following persistent EBV infection].

Yamamoto H, Hattori H, Takagi E, Morishita T, Ishikawa Y, Terakura S, Nishida T, Ito Y, Murata M, Kiyoi H

[Rinsho ketsueki] The Japanese journal of clinical hematology   59 巻 ( 3 ) 頁： 315-322   2018年

Efficacy and safety of autologous peripheral blood stem cell transplantation for Philadelphia chromosome-positive acute lymphoblastic leukemia: A study protocol for a multicenter exploratory prospective study (Auto-Ph17 study)

Nishiwaki, S; Sugiura, I; Miyata, Y; Saito, S; Sawa, M; Nishida, T; Miyamura, K; Kuwatsuka, Y; Kohno, A; Yuge, M; Kasai, M; Iida, H; Kurahashi, S; Osaki, M; Goto, T; Terakura, S; Murata, M; Nishikawa, H; Kiyoi, H

MEDICINE   96 巻 ( 52 ) 頁： e9568   2017年12月

The activated conformation of integrin β₇ is a novel multiple myeloma-specific target for CAR T cell therapy

Hosen, N; Matsunaga, Y; Hasegawa, K; Matsuno, H; Nakamura, Y; Makita, M; Watanabe, K; Yoshida, M; Satoh, K; Morimoto, S; Fujiki, F; Nakajima, H; Nakata, J; Nishida, S; Tsuboi, A; Oka, Y; Manabe, M; Ichihara, H; Aoyama, Y; Mugitani, A; Nakao, T; Hino, M; Uchibori, R; Ozawa, K; Baba, Y; Terakura, S; Wada, N; Morii, E; Nishimura, J; Takeda, K; Oji, Y; Sugiyama, H; Takagi, J; Kumanogoh, A

NATURE MEDICINE   23 巻 ( 12 ) 頁： 1436 - +   2017年12月

The activated conformation of integrin β(7) is a novel multiple myeloma-specific target for CAR T cell therapy. 査読有り

Hosen N, Matsunaga Y, Hasegawa K, Matsuno H, Nakamura Y, Makita M, Watanabe K, Yoshida M, Satoh K, Morimoto S, Fujiki F, Nakajima H, Nakata J, Nishida S, Tsuboi A, Oka Y, Manabe M, Ichihara H, Aoyama Y, Mugitani A, Nakao T, Hino M, Uchibori R, Ozawa K, Baba Y, Terakura S, Wada N, Morii E, Nishimura J, Takeda K, Oji Y, Sugiyama H, Takagi J, Kumanogoh A.

Nature Medicine   23 巻 ( 12 ) 頁： 1436-1443   2017年11月

High incidence of extensive chronic graft-versus-host disease in patients with the REG3A rs7588571 non-GG genotype. 査読有り

Koyama D, Murata M, Hanajiri R, Okuno S, Kamoshita S, Julamanee J, Takagi E, Hirano D, Miyao K, Sakemura R, Goto T, Hayakawa F, Seto A, Ozawa Y, Miyamura K, Terakura S, Nishida T, Kiyoi H.

PLoS One.   12 巻 ( 9 ) 頁： e0185213   2017年9月

Safety and persistence of WT1-specific T-cell receptor gene-transduced lymphocytes in patients with AML and MDS. 査読有り

Tawara I, Kageyama S, Miyahara Y, Fujiwara H, Nishida T, Akatsuka Y, Ikeda H, Tanimoto K, Terakura S, Murata M, Inaguma Y, Masuya M, Inoue N, Kidokoro T, Okamoto S, Tomura D, Chono H, Nukaya I, Mineno J, Naoe T, Emi N, Yasukawa M, Katayama N, Shiku H.

  130 巻 ( 18 ) 頁： 1985-1994   2017年8月

Phase II study of intrabone single unit cord blood transplantation for hematological malignancies. 査読有り

Murata M, Maeda Y, Masuko M, Onishi Y, Endo T, Terakura S, Ishikawa Y, Iriyama C, Ushijima Y, Goto T, Fujii N, Tanimoto M, Kobayashi H, Shibasaki Y, Fukuhara N, Inamoto Y, Suzuki R, Kodera Y, Matsushita T, Kiyoi H, Naoe T, Nishida T.

Cancer Science   108 巻 ( 8 ) 頁： 1634-1639   2017年6月

GvHD prophylaxis after single-unit reduced intensity conditioning cord blood transplantation in adults with acute leukemia. 査読有り

Terakura S, Kuwatsuka Y, Yamasaki S, Wake A, Kanda J, Inamoto Y, Mizuta S, Yamaguchi T, Uchida N, Kouzai Y, Aotsuka N, Ogawa H, Kanamori H, Nishiwaki K, Miyakoshi S, Onizuka M, Amano I, Fukuda T, Ichinohe T, Atsuta Y, Murata M, Teshima T.

Bone Marrow Transplant.   52 巻 ( 9 ) 頁： 1261-1267   2017年6月

Increase of bone marrow macrophages and CD8(+) T lymphocytes predict graft failure after allogeneic bone marrow or cord blood transplantation. 査読有り

Kawashima N, Terakura S, Nishiwaki S, Koyama D, Ozawa Y, Ito M, Miyamura K.

Bone Marrow Transplant.   52 巻 ( 8 ) 頁： 1164-1170   2017年4月

Impact of T-cell chimerism on relapse after cord blood transplantation for hematological malignancies: Nagoya Blood and Marrow Transplantation Group study

Yokohata, E; Kuwatsuka, Y; Ohashi, H; Terakura, S; Kawashima, N; Seto, A; Kurahashi, S; Ozawa, Y; Goto, T; Imahashi, N; Nishida, T; Miyao, K; Sakemura, R; Kato, T; Sawa, M; Kohno, A; Sao, H; Iida, H; Kiyoi, H; Naoe, T; Miyamura, K; Murata, M

BONE MARROW TRANSPLANTATION   52 巻 ( 4 ) 頁： 612 - 614   2017年4月

[Malignant lymphoma with cardiac involvement].

Terakura S, Onji M, Iriyama C, Goto T, Ushijima Y, Shimada K, Ishikawa Y, Nishida T, Hayakawa F, Murata M, Kiyoi H

[Rinsho ketsueki] The Japanese journal of clinical hematology   58 巻 ( 3 ) 頁： 239 - 242   2017年

Exploratory research for optimal GvHD prophylaxis after single unit CBT in adults: short-term methotrexate reduced the incidence of severe GvHD more than mycophenolate mofetil. 査読有り

Terakura S, Wake A, Inamoto Y, Murata M, Sakai R, Yamaguchi T, Takahashi S, Uchida N, Onishi Y, Ohashi K, Ozawa Y, Kanamori H, Yamaguchi H, Fukuda T, Ichinohe T, Takanashi M, Atsuta Y, Teshima T.

Bone Marrow Transplant.     2016年12月

Impact of graft-versus-host disease on outcomes after unrelated cord blood transplantation. 査読有り

Kanda J, Morishima Y, Terakura S, Wake A, Uchida N, Takahashi S, Ono Y, Onishi Y, Kanamori H, Aotsuka N, Ozawa Y, Ogawa H, Sakura T, Ohashi K, Ichinohe T, Kato K, Atsuta Y, Teshima T, Murata M.

Leukemia.     2016年11月

Programmed Death-Ligand 1 on Antigen-presenting Cells Facilitates the Induction of Antigen-specific Cytotoxic T Lymphocytes: Application to Adoptive T-Cell Immunotherapy. 査読有り

Goto T, Nishida T, Takagi E, Miyao K, Koyama D, Sakemura R, Hanajiri R, Watanabe K, Imahashi N, Terakura S, Murata M, Kiyoi H.

J Immunother.     2016年10月

A Tet-On Inducible System for Controlling CD19-Chimeric Antigen Receptor Expression upon Drug Administration. 査読有り

Sakemura R, Terakura S, Watanabe K, Julamanee J, Takagi E, Miyao K, Koyama D, Goto T, Hanajiri R, Nishida T, Murata M, Kiyoi H.

Cancer Immunol Res.     2016年8月

Integration of humoral and cellular HLA-specific immune responses in cord blood allograft rejection. 査読有り

Hanajiri R, Murata M, Sugimoto K, Murase M, Sakemura R, Goto T, Watanabe K, Imahashi N, Terakura S, Ohashi H, Akatsuka Y, Kurahashi S, Miyamura K, Kiyoi H, Nishida T, Naoe T.

Bone Marrow Transplant.   50 巻 ( 9 ) 頁： 1187-1194   2015年7月

Cutaneous macrophage infiltration in acute GvHD. 査読有り

Terakura S, Martin PJ, Shulman HM, Storer BE.

Bone Marrow Transplant.   50 巻 ( 8 ) 頁： 1135-1137   2015年5月

Chimerism status after unrelated donor bone marrow transplantation with fludarabine-melphalan conditioning is affected by the melphalan dose and is predictive of relapse. 査読有り

Imahashi N, Ohashi H, Terakura S, Miyao K, Sakemura R, Kato T, Sawa M, Yokohata E, Kurahashi S, Ozawa Y, Nishida T, Kiyoi H, Watamoto K, Kohno A, Kasai M, Kato C, Iida H, Naoe T, Miyamura K, Murata M; Nagoya Blood and Marrow Transplantation Group.

Annals of Hematology   94 巻 ( 7 ) 頁： 1139-1148   2015年2月

Simple and efficient generation of virus-specific T cells for adoptive therapy using anti-4-1BB antibody. 査読有り

Imahashi N, Nishida T, Goto T, Terakura S, Watanabe K, Hanajiri R, Sakemura R, Imai M, Kiyoi H, Naoe T, Murata M.

J Immunother   38 巻 ( 2 ) 頁： 62-70   2015年2月

Comparison of outcomes of 8/8 and 7/8 allele-matched unrelated BMT and single unit CBT in adults with acute leukemia 査読有り

Terakura S, Atsuta Y, Tsukada N, Kobayashi T, Tanaka M, Kanda J, Najima Y, Fukuda T, Uchida N, Takahashi S, Nagamura-Inoue T, Morishima Y, Miyamura K; Japan Society for Hematopoietic Cell Transplantation.

Biol Blood Marrow Transplant.     2015年

Target antigen density governs the efficacy of anti-CD20-CD28-CD3 ζ chimeric antigen receptor-modified effector CD8+ T cells. 査読有り

Watanabe K, Terakura S, Martens AC, van Meerten T, Uchiyama S, Imai M, Sakemura R, Goto T, Hanajiri R, Imahashi N, Shimada K, Tomita A, Kiyoi H, Nishida T, Naoe T, Murata M.

The Journal of Immunology   194 巻 ( 3 ) 頁： 911-920   2014年12月

Comparison of cord blood transplantation with unrelated bone marrow transplantation in patients older than fifty years. 査読有り

Tanaka M, Miyamura K, Terakura S, Imai K, Uchida N, Ago H, Sakura T, Eto T, Ohashi K, Fukuda T, Taniguchi S, Mori S, Nagamura-Inoue T, Atsuta Y, Okamoto S.

Biol Blood Marrow Transplant.   21 巻 ( 3 ) 頁： 517-525   2014年12月

Dexamethasone palmitate ameliorates macrophages-rich graft-versus-host disease by inhibiting macrophage functions. 査読有り

Nishiwaki S, Nakayama T, Murata M, Nishida T, Terakura S, Saito S, Kato T, Mizuno H, Imahashi N, Seto A, Ozawa Y, Miyamura K, Ito M, Takeshita K, Kato H, Toyokuni S, Nagao K, Ueda R, Naoe T.

PLoS One     2014年5月

Successful unrelated cord blood transplantation for adult acquired aplastic anemia using reduced intensity conditioning without ATG. 査読有り

Terakura S, Nishida T, Inamoto Y, Ohashi H, Naoe T, Murata M.

Immunol Lett.   160 巻 ( 1 ) 頁： 99-101   2014年1月

Unrelated cord blood transplantation vs related transplantation with HLA 1-antigen mismatch in the graft-versus-host direction. 査読有り

Kanda J, Ichinohe T, Kato S, Uchida N, Terakura S, Fukuda T, Hidaka M, Ueda Y, Kondo T, Taniguchi S, Takahashi S, Nagamura-Inoue T, Tanaka J, Atsuta Y, Miyamura K, Kanda Y; Donor/Source Working Group and HLA Working Group of the Japan Society for Hematopoietic Cell Transplantation.

Leukemia   27 巻 ( 2 ) 頁： 286-294   2012年7月

Phase II study of dose-modified busulfan by real-time targeting in allogeneic hematopoietic stem cell transplantation for myeloid malignancy. 査読有り

Kuwatsuka Y, Kohno A, Terakura S, Saito S, Shimada K, Yasuda T, Inamoto Y, Miyamura K, Sawa M, Murata M, Karasuno T, Taniguchi S, Nagafuji K, Atsuta Y, Suzuki R, Fukumoto M, Naoe T, Morishita Y; Nagoya Blood and Marrow Transplantation Group.

Cancer Science   103 巻 ( 9 ) 頁： 1688-1694   2012年7月

Generation of CD19-chimeric antigen receptor modified CD8+ T cells derived from virus-specific central memory T cells. 査読有り

Terakura S, Yamamoto TN, Gardner RA, Turtle CJ, Jensen MC, Riddell SR.

Blood   119 巻 ( 1 ) 頁： 72-82   2011年10月

A prospective dose-finding trial using a modified continual reassessment method for optimization of fludarabine plus melphalan conditioning for marrow transplantation from unrelated donors in patients with hematopoietic malignancies. 査読有り

Terakura S, Atsuta Y, Sawa M, Ohashi H, Kato T, Nishiwaki S, Imahashi N, Yasuda T, Murata M, Miyamura K, Suzuki R, Naoe T, Ito T, Morishita Y; Nagoya Blood and Marrow Transplantation Group.

Annals of Oncology   22 巻 ( 8 ) 頁： 1865-1871   2011年2月

CTL clones isolated from an HLA-Cw-mismatched bone marrow transplant recipient with acute graft-versus-host disease. 査読有り

Sugimoto K, Murata M, Terakura S, Naoe T.

The Journal of Immunology   183 巻 ( 9 ) 頁： 5991-5998   2009年10月

Impact of macrophage infiltration of skin lesions on survival after allogeneic stem cell transplantation: a clue to refractory graft-versus-host disease. 査読有り

Nishiwaki S, Terakura S, Ito M, Goto T, Seto A, Watanabe K, Yanagisawa M, Imahashi N, Tsukamoto S, Shimba M, Ozawa Y, Miyamura K.

Blood   114 巻 ( 14 ) 頁： 3113-3116   2009年7月

A single minor histocompatibility antigen encoded by UGT2B17 and presented by human leukocyte antigen-A*2902 and -B*4403. 査読有り

Terakura S, Murata M, Warren EH, Sette A, Sidney J, Naoe T, Riddell SR.

Transplantation.   83 巻 ( 9 ) 頁： 1242-1248   2007年5月

Hematopoietic engraftment in recipients of unrelated donor umbilical cord blood is affected by the CD34+ and CD8+ cell doses. 査読有り

Terakura S, Azuma E, Murata M, Kumamoto T, Hirayama M, Atsuta Y, Kodera Y, Yazaki M, Naoe T, Kato K.

Biol Blood Marrow Transplant.   13 巻 ( 7 ) 頁： 822-830   2007年4月

Short-term methotrexate could reduce early immune reactions and improve outcomes in umbilical cord blood transplantation for adults. 査読有り

Narimatsu H, Terakura S, Matsuo K, Oba T, Uchida T, Iida H, Hamaguchi M, Watanabe M, Kohno A, Murata M, Sawa M, Miyamura K, Morishita Y.

Bone Marrow Transplant.   39 巻 ( 1 ) 頁： 31-39   2006年11月

Increased risk for treatment-related mortality after bone marrow transplantation in GSTM1-positive recipients. 査読有り

Terakura S, Murata M, Nishida T, Emi N, Akatsuka Y, Morishima Y, Kodera Y, Naoe T.

Bone Marrow Transplant.   37 巻 ( 4 ) 頁： 381-386   2006年1月

A UGT2B17-positive donor is a risk factor for higher transplant-related mortality and lower survival after bone marrow transplantation. 査読有り

Terakura S, Murata M, Nishida T, Emi N, Akatsuka Y, Riddell SR, Morishima Y, Kodera Y, Naoe T.

Br J Haematol   129 巻 ( 2 ) 頁： 221-228   2005年4月

Intestinal thrombotic microangiopathy after allogeneic bone marrow transplantation: a clinical imitator of acute enteric graft-versus-host disease. 査読有り

Nishida T, Hamaguchi M, Hirabayashi N, Haneda M, Terakura S, Atsuta Y, Imagama S, Kanie T, Murata M, Taji H, Suzuki R, Morishita Y, Kodera Y.

Bone Marrow Transplant.   33 巻 ( 11 ) 頁： 1143-1150   2004年4月

テトラサイクリンシステムを用いたCD19CARの発現コントロール

酒村玲央奈、寺倉精太郎、渡邊慶介、宮尾康太郎、小山大輔、後藤辰徳、葉名尻良、西田徹也、村田誠、清井仁

第7回血液疾患免疫療法研究会学術集会 

Critical Effect of scFv Affinity to Chimeric Antigen Receptor Functions

Comparison of Outcomes of Unrelated BM and CB transplants in Young Adult Leukemia Patients: An Updated Results of Japanese Registration Data. 国際会議

Terakura S, Atsuta Y, Tsukada N, Kobayashi T, Tanaka M, Kanda J, Ohashi K, Fukuda T, Uchida N, Takahashi S, Nagamura-Inoue T, Morishima Y, Miyamura K.

56th Annual Meeting of American Society of Hematology 

Excessively High-Affinity Single-Chain Fragment Variable Region in a Chimeric Antigen Receptor Can Counteract T-cell Proliferation. 国際会議

Watanabe K, Terakura S, Uchiyama S, Martens AC, van Meerten T, Nishida T, Naoe T, Kiyoi H, Murata M.

56th Annual Meeting of American Society of Hematology 

Anti-CD20 chimeric antigen receptor+ T cells can recognize remarkably low target antigen expression.

Comparison of unrelated bone marrow and umbilical cord blood transplants in young adult leukemia.

キメラ抗原レセプター遺伝子導入T細胞を用いた細胞治療の今後

寺倉精太郎

第63回日本輸血・細胞治療学会東海支部例会 

キメラ抗原受容体単鎖抗体部分の強すぎる親和性は抗原刺激後のT細胞増殖を阻害する

渡邊慶介、 寺倉精太郎、今井美沙、酒村玲央奈、後藤辰徳、葉名尻良、今橋伸彦、島田和之、冨田章裕、西田徹也、村田誠、清井仁

第6回血液疾患免疫療法研究会学術集会 

新規CD20キメラ抗原レセプター遺伝子導入T細胞の樹立とCD20低発現標的に対する効果の検討

渡邊慶介、 寺倉精太郎、後藤辰徳、葉名尻良、今橋伸彦、西田徹也、村田誠、直江知樹

第36回日本造血細胞移植学会 

同種臍帯血移植を行い良好な生着・生存を得た成人再生不良性貧血の3例

寺倉精太郎、後藤辰徳、葉名尻良、渡邊慶介、今橋伸彦、西田徹也、村田誠、直江知樹

第36回日本造血細胞移植学会 

Anti-CD20 Chimeric Antigen Receptor Transduced T cells Can Recognize Very Low Antigen Expression: Determination of the Lower Threshold Required to Activate the CAR-T Cells. 国際会議

Watanabe K, Terakura S, Goto T, Hanajiri R, Imahashi N, Shimada K, Nishida T, Tomita A, Murata M, Naoe T

55th Annual Meeting of American Society of Hematology 

免疫抑制的腫瘍微小環境を打破する遺伝子導入Tリンパ球の開発とその機能解析

2015年4月 - 2018年3月

科学研究費補助金  基盤研究(C)

新しいコンセプトに基づく変異FLT3に対する標的治療法の開発

2015年4月 - 2018年3月

科学研究費補助金  基盤研究(B)

清井仁

免疫抑制的腫瘍微小環境を打破する遺伝子導入Tリンパ球の開発とその機能解析

研究課題/研究課題番号：15K09497  2015年4月 - 2018年3月

寺倉 精太郎

キメラ抗原レセプターを遺伝子導入したリンパ球細胞の作 成方法の至適化

2012年4月 - 2015年3月

科学研究費補助金  若手研究(B)