Organization
Nagoya University Hospital Clinical Oncology and Chemotherapy Lecturer of hospital
Title
Lecturer of hospital
YANAGAWA Madoka
Degree 1
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博士（医学） （ 2012.3 名古屋大学 ）
Research Interests 4
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認知症
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高齢者のがん治療
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ACP
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CGA
Research Areas 3
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Life Science / General internal medicine / 認知症
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Life Science / Cognitive and brain science
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Others / Others / Community Healthcare and Geriatrics
Current Research Project and SDGs 1
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高齢者に対する過剰でも過小でもない的確ながん治療を検討する
Research History 2
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Nagoya University Lecturer of hospital
2023.4
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名古屋大学医学部附属病院老年内科 医員 助教
2008.4 - 2021.3
Country：Japan
Education 3
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Nagoya University Graduate School, Division of Medical Sciences
- 2012.3
Country： Japan
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Tokai University Faculty of Medicine
2002.4 - 2006.4
Country： Japan
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Waseda University Faculty of Humanities and Social Sciences
- 1993.3
Country： Japan
Professional Memberships 3
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日本老年学会
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日本認知症学会
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日本内科学会
Papers 21
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Selection of chemotherapy for older patients with pancreatic cancer based on geriatric assessment Reviewed International journal
Maeda, O; Matsuoka, A; Yanagawa, M; Muroyama, Y; Watanabe, K; Liang, Y; Ishikawa, T; Ohno, E; Kawashima, H; Umegaki, H; Kuzuya, M; Ando, Y
JOURNAL OF GERIATRIC ONCOLOGY Vol. 13 ( 8 ) page： 1260 - 1263 2022.11
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Cerebral pathological findings in long-lived patient with Werner syndrome and dementia Reviewed International journal
Kuzuya, M; Shi, RQ; Yanagawa, M; Watanabe, K; Samizo, S; Ando, R; Miyahara, H; Iwasaki, Y; Yoshida, M
GERIATRICS & GERONTOLOGY INTERNATIONAL Vol. 21 ( 8 ) page： 743 - 745 2021.8
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Long-lived Werner syndrome patient autopsy report: The presence of liver cirrhosis Reviewed International journal
Kuzuya, M; Shi, RQ; Yanagawa, M; Watanabe, K; Samizo, S; Ando, R
GERIATRICS & GERONTOLOGY INTERNATIONAL Vol. 21 ( 5 ) page： 433 - 435 2021.5
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The Japan Geriatrics Society consensus statement "recommendations for older persons to receive the best medical and long-term care during the COVID-19 outbreak-considering the timing of advance care planning implementation" Reviewed International journal
Kuzuya, M; Aita, K; Katayama, Y; Katsuya, T; Nishikawa, M; Hirahara, S; Miura, H; Yanagawa, M; Arai, H; Iijima, K; Okochi, J; Kozaki, K; Yamaguchi, Y; Rakugi, H; Akishita, M
GERIATRICS & GERONTOLOGY INTERNATIONAL Vol. 20 ( 12 ) page： 1112 - 1119 2020.12
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Plasma orexin-A levels in patients with delirium. Reviewed International journal
Nakashima H, Umegaki H, Yanagawa M, Komiya H, Watanabe K, Kuzuya M
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society Vol. 19 ( 6 ) page： 628 - 630 2019.11
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Selection of chemotherapy based on geriatric assessment for elderly patients with pancreatic cancer Reviewed International journal
Maeda, O; Matsuoka, A; Yanagawa, M; Muroyama, Y; Kuzuya, M; Ando, Y
ANNALS OF ONCOLOGY Vol. 30 page： 131 - 131 2019.10
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Plasma orexin-A-like immunoreactivity levels and renal function in patients in a geriatric ward. Reviewed International journal
Nakashima H, Umegaki H, Yanagawa M, Komiya H, Watanabe K, Kuzuya M
Peptides Vol. 118 page： 170092 2019.8
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Polypharmacy and gait speed in individuals with mild cognitive impairment. Reviewed International journal
Umegaki H, Yanagawa M, Komiya H, Matsubara M, Fujisawa C, Suzuki Y, Kuzuya M
Geriatrics & gerontology international Vol. 19 ( 8 ) page： 730 - 735 2019.8
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Maximum gait speed is associated with a wide range of cognitive functions in Japanese older adults with a Clinical Dementia Rating of 0.5 Reviewed International journal
Umegaki Hiroyuki, Makino Taeko, Yanagawa Madoka, Nakashima Hirotaka, Kuzuya Masafumi, Sakurai Takashi, Toba Kenji
GERIATRICS & GERONTOLOGY INTERNATIONAL Vol. 18 ( 9 ) page： 1323 - 1329 2018.9
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[Role of Comprehensive Geriatric Assessment(CGA)in Elderly Cancer Treatment]. Invited
Yanagawa M
Gan to kagaku ryoho. Cancer & chemotherapy Vol. 49 ( 1 ) page： 24 - 27 2022.1
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脳波データを用いたMMSEスコアの推定に関する検討
三輪晃暉・高倉健太郎・吉川大弘・古橋 武・寶珠山 稔・牧野多恵子・柳川まどか・鈴木裕介・梅垣宏行・葛谷雅文
信学技報 Vol. vol. 117 ( no. 417, NC2017-51 ) page： pp. 5-10 2018.1
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Study on Estimation of MMSE Score by Using the Latency of P300 and Alpha Wave Reviewed
Miwa Koki, Yoshikawa Tomohiro, Furuhashi Takeshi, Hoshiyama Minoru, Makino Taeko, Yanagawa Madoka, Suzuki Yusuke, Umegaki Hiroyuki, Kuzuya Masafumi
2018 JOINT 10TH INTERNATIONAL CONFERENCE ON SOFT COMPUTING AND INTELLIGENT SYSTEMS (SCIS) AND 19TH INTERNATIONAL SYMPOSIUM ON ADVANCED INTELLIGENT SYSTEMS (ISIS) page： 195 - 199 2018
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The prevalence of homebound individuals in the elderly population: A survey in a city area in Japan
Umegaki H, Yanagawa M, Nakashima H, Makino T, Kuzuya M
Nagoya Journal of Medical Science ( 77(3) ) page： 439–446 2015.8
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Burden reduction of caregivers for users of care services provided by the public long-term care insurance system in Japan Reviewed
Umegaki H, Yanagawa M, Nonogaki Z, Nakashima H, Kuzuya M, Endo H
Archives of Gerontology and Geriatrics Vol. 58 ( 1 ) page： 130-133 2014
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Cognitive impairments and functional declines in older adults at high risk for care needs Reviewed
Umegaki H, Suzuki Y, Yanagawa M, Nonogaki Z, Nakashima H, Kuzuya M, Endo H
Gerontol Geriatr Int Vol. 13 ( 1 ) page： 77-82 2013
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Relationship between Small Cerebral White Matter Lesions and Cognitive Function in Patients with Alzheimer's Disease and Amnestic Mild Cognitive Impairment Reviewed
MakinoT, Umegaki H, Suzuki Y, Yanagawa M, Nonogaki Z, Nakashima H, Kuzuya M
Gerontol Geriatr Int 2013
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Cognitive dysfunction: an emerging concept of a new diabetic complication Reviewed
Umegaki H, Hayashi T, Nomura H, Yanagawa M, Nonogaki Z, Nakshima H, Kuzuya M
Gerontol Geriatr Int Vol. 13 ( 1 ) page： 28-34 2013
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Falls in elderly at high risk of requiring care Reviewed
Umegaki H, Suzuki Y, Yanagawa M, Nonogaki Z, Endo H
Geriatr Gerontol Int Vol. 12 ( suppl 1 ) page： 147-148 2012
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Dysphagia in older adults at high risk of requiring care Reviewed
Umegaki H, Suzuki Y, Yanagawa M, Nonogaki Z, Nakashima H, Endo H
Geriatr Gerontol Int Vol. 12 ( 2 ) page： 359-361 2012
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The association of lower hemoglobin level with depressive mood in Reviewed
Umegaki H, Yanagawa M, Endo H
Geriatr Gerontol Int Vol. 11 ( 3 ) page： 262-266 2011
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Association between improvements in insulin resistance and changes in cognitive function in elderly diabetic patients with normal cognitive function. Reviewed
Yanagawa M, Umegaki H, Uno T, Oyun K, Kawano N, Maeno H, Yamanouchi K, Sato Y
Geriatr Gerontol Int Vol. 11 ( 3 ) page： 341-347 2011
Books 1
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かかりつけ医のための老年病100の解決法 秋下雅弘 編
柳川まどか（ Role： Joint author）
メディカルビュー社 2015
Presentations 9
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Maximum gait speed is associated with a wide range of cognitive functions in Japanese subjects with a clinical dementia rating of 0.5. International conference
Hiroyuki Umegaki, Taeko Makino, Madoka Yanagawa, Hirotaka Nakashima, Masafumi Kuzuya, Takashi Sakurai, Kenji Toba
Advances in Alzheimer's and Parkinson' s Therapies an AAT-AD/PD focus Meeting
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生活習慣病がアルツハイマー型認知症に与える影響の検討
栁川まどか、梅垣宏行、牧野多恵子、中島宏貴、鈴木裕介、葛谷雅文
第３４回日本認知症学会学術集会
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２４週間の運動介入により認知機能が改善し髄液バイオマーカーに変化を認めた軽度認知機能障害（mild cognitive impairment＝MCI）８０歳女性の一症例
栁川まどか、梅垣宏行、中島宏貴、小宮仁、牧野多恵子、鈴木裕介、葛谷雅文
第２６回日本老年医学会東海地方会
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アルツハイマー型認知症における生活習慣病の影響の検討
栁川まどか、梅垣宏行、牧野多恵子、中島宏貴、藤沢知里、鈴木裕介、葛谷雅文
第57回日本老年医学会学術集会
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アルツハイマー病に対する糖尿病の影響の検討
柳川まどか、梅垣宏行、牧野多恵子、中嶋宏貴、藤澤知里、鈴木裕介、葛谷雅文
第３３回認知症学会学術集会
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アルツハイマー病発症が危惧される１型糖尿病３７歳女性の一症例
栁川まどか、梅垣宏行、牧野多恵子、中嶋宏貴、藤沢知里、鈴木祐介、葛谷雅文
第２５回日本老年医学会東海地方会
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老年学会 高齢者技能者研修会 ファシリテーター 2013年、2014年
栁川まどか
第２５回日本老年医学会東海地方会
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アルツハイマー型認知症およびＭＣＩ患者における糖尿病の影響の検討
柳川まどか、梅垣宏行、牧野多恵子、野々垣禅、中島宏貴、一柳知里、鈴木裕介、葛谷雅文
第５６回日本老年医学会学術集会
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アルツハイマー病とＭＣＩ患者に対する生活習慣病の影響
柳川まどか、梅垣宏行、鈴木裕介、牧野多恵子、野々垣禅、中嶋宏貴、葛谷雅文
第３２回日本認知症学会学術集会
KAKENHI (Grants-in-Aid for Scientific Research) 4
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運動による認知機能低下予防効果の機序の解明
2015.4 - 2018.3
科学研究費補助金 基盤研究(C)
Authorship：Principal investigator
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Improvement of geriatric assessment for older patients received surgery and biomarker discovery
Grant number：17K01841 2017.4 - 2023.3
Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
TANAKA Chie
Authorship：Coinvestigator(s) Grant type：Competitive
Little knowledge is available for postsurgical changes in cognitive and physical functions that may be useful for considering indication for surgery in elderly patients with gastric cancer. We recruited patients older than 75 years for whom gastrectomy for gastric cancer had been planned, and assessed their cognitive and physical functions, and daily activities before surgery (baseline), upon discharge, and at 6 months after surgery (POM 6). There were no significant decreases in MMSE scores between baseline and at POM 6. As many as 13% of patients were found to have the functional decline on the IADL after surgery. The variable significantly associated with a functional decline in BADL was postoperative complications. To conclude, postoperative cognitive functions did not significantly decline when compared with the baseline scores, although postoperative BADL scores of patients who experienced postoperative complications were significantly lower than those who did not.
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Elucidation of the mechanism of the cognitive functional decline protective efficacy by the exercise
Grant number：15K08908 2015.4 - 2019.3
Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
YANAGAWA MADOKA, KUZUYA masafumi, KOMIYA hitoshi, WATANABE kazuhisa
Authorship：Principal investigator Grant type：Competitive
Grant amount：\4940000 （ Direct Cost: \3800000 、 Indirect Cost：\1140000 ）
It is necessary to clarify the characteristic that is in a state called preclinical AD to prevent the onset of AD. I call the state that only power to memorize decreases MCI and call a stage only with conscious forgetfulness more with SCI for a pre-stage. And it’s suggested that exercise may be a better way to prevent dementia, thought its mechanism is unclear.We examined the cognitive protection effect of exercise before and after exercise intervention in patients of MCI, I was going to perform a similar examination for the patients of SCI , but careful correspondence is necessary about the CSF collection of the study concerned .And it is difficult unexpectedly to gather a cerebrospinal fluid from a patient of healthy SCI, and what cannot possibly achieve the number of the aims becomes clear. In addition, similar results of research were given by each country and did decision to stop a study because significant difference appeared neither..
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Grant number：15K08907 2015.4 - 2018.3
Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)
UMEGAKI Hiroyuki
Authorship：Coinvestigator(s) Grant type：Competitive
Past studies suggested that insulin resistance (IR) may be involved in the mechanism of cognitive impairment in the older subjects. In the current study we studied the association of IR and cognitive function in the older subjects with mild cognitive decline. The number of 40 subjects was involved in the analysis. All the subjects had the assessments of fasting serum glucose and insulin with several cognitive assessments including Mini Mental State Examination (MMSE). The subjects were divided into 2 groups according to the score of MMSE at the cut-off of 23/24. The level of serum insulin was statistically significantly higher in the lower MMSE group than the higher group, while there was no difference in glucose and HbA1c levels. The results suggested that IR is associated with cognitive dysfunction in the older subjects.
Teaching Experience (On-campus) 5
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高齢者の終末期医療ACP
2023
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ポリクリ
2023
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高齢者の終末期医療
2018
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高齢者の終末期医療
2017
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高齢者の終末期医療
2016
Academic Activities 1
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老年腫瘍研究会運営
Role(s)：Planning, management, etc., Panel moderator, session chair, etc.
2021.4