Association of calciprotein particles with serum phosphorus among patients undergoing conventional and extended-hours haemodialysis

Nishibori, N; Okazaki, M; Miura, Y; Hishida, M; Kurasawa, S; Imaizumi, T; Kato, N; Kosugi, T; Kuro-o, M; Kasuga, H; Kaneda, F; Maruyama, S

CLINICAL KIDNEY JOURNAL   17 巻 ( 6 ) 頁： sfae121   2024年6月

Clinical impact of proteinuria and hematuria remission criteria in IgA nephropathy patients defined by the Japanese Society of Nephrology

Yasuda, Y; Kaihan, AB; Kaihan, AN; Tanaka, A; Imaizumi, T; Maeda, K; Kato, N; Kosugi, T; Maruyama, S

NEPHROLOGY DIALYSIS TRANSPLANTATION   39 巻   2024年5月

Clinical impact of proteinuria and hematuria remission criteria in IgA nephropathy patients defined by the Japanese Society of Nephrology

Yasuda, Y; Kaihan, AB; Kaihan, AN; Tanaka, A; Imaizumi, T; Maeda, K; Kato, N; Kosugi, T; Maruyama, S

NEPHROLOGY DIALYSIS TRANSPLANTATION   39 巻   頁： I736 - I737   2024年5月

Rationale and design of the Japanese Biomarkers in Nephrotic Syndrome (J-MARINE) study

Kurasawa, S; Kato, S; Ozeki, T; Akiyama, S; Ishimoto, T; Mizuno, M; Tsuboi, N; Kato, N; Kosugi, T; Maruyama, S

CLINICAL AND EXPERIMENTAL NEPHROLOGY   28 巻 ( 5 ) 頁： 431 - 439   2024年5月

Case report: A family of atypical hemolytic uremic syndrome involving a <i>CFH::CFHR1</i> fusion gene and <i>CFHR3-1-4-2</i> gene duplication

Tasaki, Y; Tsujimoto, H; Yokoyama, T; Sugimoto, N; Kitajima, S; Fujii, H; Hidaka, Y; Kato, N; Maruyama, S; Inoue, N; Wada, T

FRONTIERS IN IMMUNOLOGY   15 巻   頁： 1360855   2024年3月

Clinical characteristics of anti-GBM disease with thrombotic microangiopathy: a case report and literature review

Nakamura, Y; Kato, N; Tatematsu, Y; Arai, Y; Mori, N; Shibata, K; Yamazaki, M; Yasui, H; Fujiwara, S; Yamakawa, T; Maruyama, S

CEN CASE REPORTS   13 巻 ( 1 ) 頁： 37 - 44   2024年2月

Overlapping Atypical Hemolytic Uremic Syndrome and C3 Glomerulopathy with Mutation in <i>CFI</i> in a Japanese Patient: A Case Report

Osawa, K; Yamamoto, S; Yamano, Y; Kita, A; Okamoto, K; Kato, N; Tatematsu, Y; Kojima, F; Ohya, M; Hara, S; Murata, SI; Inoue, N; Maruyama, S; Araki, SI

INTERNAL MEDICINE   63 巻 ( 12 ) 頁： 1777 - 1782   2024年

Basigin is released in extracellular vesicles derived from the renal tubular epithelium in response to albuminuria

Watanabe, T; Maeda, K; Kato, N; Seko, H; Sugimura, M; Sato, Y; Ryuge, A; Kato, S; Kadomatsu, K; Maruyama, S; Kosugi, T

NEPHROLOGY   28 巻 ( 11 ) 頁： 629 - 638   2023年11月

IgA-dominant glomerulonephritis with DNAJB9-negative fibrillar polytypic immunoglobulin deposits in the subepithelium

Muto, R; Maeda, K; Fukui, S; Saito, S; Kato, N; Kosugi, T; Shimizu, A; Maruyama, S

CEN CASE REPORTS   12 巻 ( 3 ) 頁： 323 - 328   2023年8月

Relapse of atypical hemolytic uremic syndrome triggered by COVID-19: a lesson for the clinical nephrologist

Uwatoko, R; Shindo, M; Hashimoto, N; Iio, R; Ueda, Y; Tatematsu, Y; Kato, N; Maruyama, S; Hayashi, T

JOURNAL OF NEPHROLOGY   36 巻 ( 5 ) 頁： 1439 - 1442   2023年6月

Application of a scoring system in Japanese patients diagnosed with atypical hemolytic uremic syndrome to assess the relationship between the score and clinical responses to eculizumab

Wada, H; Teranishi, H; Shimono, A; Kato, N; Maruyama, S; Matsumoto, M

THROMBOSIS JOURNAL   21 巻 ( 1 ) 頁： 43   2023年4月

Efficacy of On-line Hemodiafiltration for Rhabdomyolysis Presenting with Acute Kidney Injury Due to Unexpected Drug Abuse

Sato, N; Inagaki, K; Takanashi, M; Muto, R; Kato, N; Maruyama, S; Akahori, T

INTERNAL MEDICINE   62 巻 ( 19 ) 頁： 2865 - 2870   2023年

Systematic characterization of seed overlap microRNA cotargeting associated with lupus pathogenesis

Kitai, H; Kato, N; Ogami, K; Komatsu, S; Watanabe, Y; Yoshino, S; Koshi, E; Tsubota, S; Funahashi, Y; Maeda, T; Furuhashi, K; Ishimoto, T; Kosugi, T; Maruyama, S; Kadomatsu, K; Suzuki, H

BMC BIOLOGY   20 巻 ( 1 ) 頁： 248   2022年11月

Abnormal foreshortening of a Flow Re-Direction Endoluminal Device caused by in-stent thrombosis immediately after deployment br

Otsuka, T; Izumi, T; Nishihori, M; Tsukada, T; Goto, S; Ikezawa, M; Kato, N; Nakano, M; Uda, K; Yokoyama, K; Araki, Y; Saito, R

NAGOYA JOURNAL OF MEDICAL SCIENCE   84 巻 ( 4 ) 頁： 884 - 889   2022年11月

Adrenomedullin for biologic-resistant Crohn's disease: A randomized, double-blind, placebo-controlled phase 2a clinical trial

Kita, T; Ashizuka, S; Takeda, T; Matsumoto, T; Ohmiya, N; Nakase, H; Motoya, S; Ohi, H; Mitsuyama, K; Hisamatsu, T; Kanmura, S; Kato, N; Ishihara, S; Nakamura, M; Moriyama, T; Saruta, M; Nozaki, R; Yamamoto, S; Inatsu, H; Watanabe, K; Kitamura, K

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY   37 巻 ( 11 ) 頁： 2051 - 2059   2022年11月

ECULIZUMAB FOR ADULT PATIENTS WITH ATYPICAL HAEMOLYTIC-UREMIC SYNDROME: FULL DATASET ANALYSIS OF POST-MARKETING SURVEILLANCE IN JAPAN

Maruyama, S; Ikeda, Y; Kaname, S; Kato, N; Matsumoto, M; Ishikawa, Y; Shimono, A; Miyakawa, Y; Nangaku, M; Shibagaki, Y; Okada, H

NEPHROLOGY DIALYSIS TRANSPLANTATION   37 巻   頁： I231 - I232   2022年5月

A novel renal perivascular mesenchymal cell subset gives rise to fibroblasts distinct from classic myofibroblasts

Minatoguchi, S; Saito, S; Furuhashi, K; Sawa, Y; Okazaki, M; Shimamura, Y; Kaihan, AB; Hashimoto, Y; Yasuda, Y; Hara, A; Mizutani, Y; Ando, R; Kato, N; Ishimoto, T; Tsuboi, N; Esaki, N; Matsuyama, M; Shiraki, Y; Kobayashi, H; Asai, N; Enomoto, A; Maruyama, S

SCIENTIFIC REPORTS   12 巻 ( 1 ) 頁： 5389   2022年3月

The 30-year Natural History of Non-classic Fabry Disease with an R112H Mutation

Muto, R; Inagaki, K; Kato, N; Maruyama, S; Akahori, T

INTERNAL MEDICINE   61 巻 ( 11 ) 頁： 1727 - 1730   2022年

X-chromosome inactivation patterns in females with Fabry disease examined by both ultra-deep RNA sequencing and methylation-dependent assay

Rossanti, R; Nozu, K; Fukunaga, A; Nagano, C; Horinouchi, T; Yamamura, T; Sakakibara, N; Minamikawa, S; Ishiko, S; Aoto, Y; Okada, E; Ninchoji, T; Kato, N; Maruyama, S; Kono, K; Nishi, S; Iijima, K; Fujii, H

CLINICAL AND EXPERIMENTAL NEPHROLOGY   25 巻 ( 11 ) 頁： 1224 - 1230   2021年11月

Basigin deficiency prevents anaplerosis and ameliorates insulin resistance and hepatosteatosis

Ryuge, A; Kosugi, T; Maeda, K; Banno, R; Gou, Y; Zaitsu, K; Ito, T; Sato, Y; Hirayama, A; Tsubota, S; Honda, T; Nakajima, K; Ozaki, T; Kondoh, K; Takahashi, K; Kato, N; Ishimoto, T; Soga, T; Nakagawa, T; Koike, T; Arima, H; Yuzawa, Y; Minokoshi, Y; Maruyama, S; Kadomatsu, K

JCI INSIGHT   6 巻 ( 20 )   2021年10月

A Case of TAFRO Syndrome with Two Consecutive Renal Biopsies Following the Pathological Course of the Kidney

Kato, N; Hasegawa, T; Muto, R; Tanaka, A; Sato, Y; Maeda, K; Furuhashi, K; Saito, S; Kosugi, T; Maruyama, S

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY   32 巻 ( 10 ) 頁： 823 - 824   2021年10月

Eculizumab for Treatment of Recurrent Pregnancy-Triggered Atypical Hemolytic-Uremic Syndrome with a Mutation in Complement 3: A Case Report

Miyabe, Y; Nakai, A; Watanabe, K; Karasawa, K; Kato, N; Maruyama, S; Moriyama, T; Nitta, K

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY   32 巻 ( 10 ) 頁： 826 - 827   2021年10月

The ISN/RPS 2016 classification predicts renal prognosis in patients with first-onset class III/IV lupus nephritis

Hachiya, A; Karasawa, M; Imaizumi, T; Kato, N; Katsuno, T; Ishimoto, T; Kosugi, T; Tsuboi, N; Maruyama, S

SCIENTIFIC REPORTS   11 巻 ( 1 ) 頁： 1525   2021年1月

Acquired Fanconi Syndrome in a Patient with Nontyphoidal <i>Salmonella</i> Bacteremia

Ryuge, A; Saito, S; Morioka, H; Hachiya, A; Kato, N; Ishimoto, T; Kosugi, T; Maruyama, S

INTERNAL MEDICINE   60 巻 ( 5 ) 頁： 761 - 764   2021年

Refractory Hypotension Caused by Selenium Deficiency in a Patient on Peritoneal Dialysis

Ryuge, A; Kim, H; Suzuki, Y; Okazaki, M; Kojima, H; Saito, S; Kato, N; Ishimoto, T; Kosugi, T; Maruyama, S; Mizuno, M

INTERNAL MEDICINE   60 巻 ( 15 ) 頁： 2461 - 2464   2021年

THE ROLE OF FRUCTOSE METABOLISM IN VASCULAR ENDOTHELIAL FUNCTION IN DIABETES

Ishimoto, T; Doke, T; Hayasaki, T; Kato, N; Maruyama, S

NEPHROLOGY   25 巻   頁： 62 - 62   2020年10月

EXOSOMES FROM CKD PATIENTS HAVE ATHEROSCLEROGENIC PROPERTIES

Kato, N; Nishio, F; Ishimoto, T; Kosugi, T; Maruyama, S

NEPHROLOGY   25 巻   頁： 62 - 62   2020年10月

Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis.

Lovisa S, Fletcher-Sananikone E, Sugimoto H, Hensel J, Lahiri S, Hertig A, Taduri G, Lawson E, Dewar R, Revuelta I, Kato N, Wu CJ, Bassett RL Jr, Putluri N, Zeisberg M, Zeisberg EM, LeBleu VS, Kalluri R

Science signaling   13 巻 ( 635 )   2020年6月

Ectopic Relapse of Anti-neutrophil Cytoplasmic Antibody-associated Pituitary Vasculitis with No Elevation of Anti-neutrophil Cytoplasmic Antibodies after Renal Remission

Muto, R; Inagaki, K; Sato, N; Sameshima, T; Nagakura, Y; Baba, S; Kato, N; Maruyama, S; Akahori, T

INTERNAL MEDICINE   59 巻 ( 24 ) 頁： 3187 - 3193   2020年

Fructose increases the activity of sodium hydrogen exchanger in renal proximal tubules that is dependent on ketohexokinase

Hayasaki, T; Ishimoto, T; Doke, T; Hirayama, A; Soga, T; Furuhashi, K; Kato, N; Kosugi, T; Tsuboi, N; Lanaspa, MA; Johnson, RJ; Maruyama, S; Kadomatsu, K

JOURNAL OF NUTRITIONAL BIOCHEMISTRY   71 巻   頁： 54 - 62   2019年9月

miR-146a targeted to splenic macrophages prevents sepsis-induced multiple organ injury

Funahashi, Y; Kato, N; Masuda, T; Nishio, F; Kitai, H; Ishimoto, T; Kosugi, T; Tsuboi, N; Matsuda, N; Maruyama, S; Kadomatsu, K

LABORATORY INVESTIGATION   99 巻 ( 8 ) 頁： 1130 - 1142   2019年8月

CD147/Basigin Deficiency Prevents the Development of Podocyte Injury through FAK Signaling

Yoshioka, T; Kosugi, T; Masuda, T; Watanabe, T; Ryuge, A; Nagaya, H; Maeda, K; Sato, Y; Katsuno, T; Kato, N; Ishimoto, T; Yuzawa, Y; Maruyama, S; Kadomatsu, K

AMERICAN JOURNAL OF PATHOLOGY   189 巻 ( 7 ) 頁： 1338 - 1350   2019年7月

NOVEL PATHOPHYSIOLOGIC ROLE OF MIR-146A FOR SPLENIC MACROPHAGE INTERFERENCE IN SEPSIS-RELATED KIDNEY INJURY

Funahashi, Y; Kato, N; Ishimoto, T; Kosugi, T; Maruyama, S

NEPHROLOGY DIALYSIS TRANSPLANTATION   34 巻   2019年6月

Therapeutic efficacy of rituximab for the management of adult-onset steroid-dependent nephrotic syndrome: a retrospective study

Katsuno, T; Masuda, T; Saito, S; Kato, N; Ishimoto, T; Kato, S; Kosugi, T; Tsuboi, N; Kitamura, H; Tsuzuki, T; Ito, Y; Maruyama, S

CLINICAL AND EXPERIMENTAL NEPHROLOGY   23 巻 ( 2 ) 頁： 207 - 214   2019年2月

Essential points from Evidence-based Clinical Practice Guidelines for Chronic Kidney Disease 2018

Okada Hirokazu, Yasuda Yoshinari, Kashihara Naoki, Asahi Koichi, Ito Takafumi, Kaname Shinya, Kanda Eiichiro, Kanno Yoshihiko, Shikata Kenichi, Shibagaki Yugo, Tsuchiya Ken, Tsuruya Kazuhiko, Nagata Daisuke, Narita Ichiei, Nangaku Masaomi, Hattori Motoshi, Hamano Takayuki, Fujimoto Shouichi, Moriyama Toshiki, Yamagata Kunihiro, Yamamoto Ryohei, Wakasugi Minako, Ashida Akira, Usui Joichi, Kawamura Kazuko, Kitamura Kenichiro, Konta Tsuneo, Suzuki Yusuke, Tsuruoka Shuichi, Nishio Saori, Hamano Takayuki, Fujii Naohiko, Fujii Hideki, Wada Takehiko, Yokoyama Hitoshi, Aoki Katsunori, Akiyama Daiichiro, Araki Shin-ichi, Arima Hisatomi, Ishikawa Eiji, Ishikura Kenji, Ishizuka Kiyonobu, Ishimoto Takuji, Ishimoto Yu, Iseki Kunitoshi, Itabashi Mitsuyo, Ichioka Satoko, Ichikawa Kazunobu, Ichikawa Daisuke, Inoue Shuji, Imai Toshimi, Imamura Hideaki, Iwata Yasunori, Iwazu Yoshitaka, Usui Toshiaki, Uchida Keiko, Egawa Masahiro, Ohara Shinichiro, Omori Norio, Okada Rieko, Okuda Yusuke, Ozeki Takaya, Obata Yoko, Kai Hirayasu, Kato Noritoshi, Kanasaki Keizo, Kaneko Yoshikatsu, Kabasawa Hideyuki, Kawaguchi Takehiko, Kawasaki Yukihiko, Kawashima Keisuke, Kawano Haruna, Kikuchi Kan, Kihara Masao, Kimura Yoshiki, Kurita Noriaki, Koike Kentaro, Koizumi Masahiro, Kojima Chiari, Goto Shunsuke, Konomoto Takao, Kohagura Kentaro, Komatsu Hiroyuki, Komaba Hirotaka, Saito Chie, Sakai Yukinao, Sakaguchi Yusuke, Satonaka Hiroshi, Jimi Kanako, Shimizu Akihiro, Shimizu Sayaka, Shirai Sayuri, Shinzawa Maki, Sugiyama Kazuhiro, Suzuki Tomo, Suzuki Hitoshi, Suyama Kazuhide, Segawa Hiroyoshi, Takahashi Kazuya, Tanaka Kenichi, Tanaka Tetsuhiro, Tsunoda Ryoya, Tsuruta Yuki, Nakakura Hyogo, Nagasawa Yasuyuki, Nakanishi Koichi, Nagahama Masahiko, Nakaya Izaya, Nanami Masayoshi, Niihata Kakuya, Nishi Shinichi, Nishiwaki Hiroki, Hasegawa Shoko, Hasegawa Midori, Hanada Ken, Hayashi Hiroki, Harada Ryoko, Hishida Manabu, Hirano Daishi, Hirahashi Junichi, Hirama Akio, Hirayama Kouichi, Fukagawa Masafumi, Fukuda Akihiro, Fujii Yoshiyuki, Fujisaki Kiichiro, Furuya Fumihiko, Hoshino Junichi, Hosojima Michihiro, Honda Kenjiro, Masuda Takahiro, Matsui Kosuke, Matsukuma Yuta, Matsumura Hideki, Mii Akiko, Miura Kenichiro, Mitobe Michihiro, Miyasato Yoshikazu, Miyamoto Satoshi, Miwa Saori, Yazawa Masahiko, Yata Yusuke, Yamamoto Yoshihiro, Watanabe Kimio, Hosojima Michihiro

CLINICAL AND EXPERIMENTAL NEPHROLOGY   23 巻 ( 1 ) 頁： 1-15   2019年1月

Investigation on the benefits of mycophenolate mofetil and therapeutic drug monitoring in the treatment of Japanese patients with lupus nephritis

Katsuno, T; Ozaki, T; Ozeki, T; Hachiya, A; Kim, H; Kato, N; Ishimoto, T; Kato, S; Kosugi, T; Tsuboi, N; Mizuno, M; Ito, Y; Maruyama, S

CLINICAL AND EXPERIMENTAL NEPHROLOGY   22 巻 ( 6 ) 頁： 1341 - 1350   2018年12月

Lacking ketohexokinase-A exacerbates renal injury in streptozotocin-induced diabetic mice

Doke, T; Ishimoto, T; Hayasaki, T; Ikeda, S; Hasebe, M; Hirayama, A; Soga, T; Kato, N; Kosugi, T; Tsuboi, N; Lanaspa, MA; Johnson, RJ; Kadomatsu, K; Maruyama, S

METABOLISM-CLINICAL AND EXPERIMENTAL   85 巻   頁： 161 - 170   2018年8月

The clinical relevance of plasma CD147/basigin in biopsy-proven kidney diseases

Mori, Y; Masuda, T; Kosugi, T; Yoshioka, T; Hori, M; Nagaya, H; Maeda, K; Sato, Y; Kojima, H; Kato, N; Ishimoto, T; Katsuno, T; Yuzawa, Y; Kadomatsu, K; Maruyama, S

CLINICAL AND EXPERIMENTAL NEPHROLOGY   22 巻 ( 4 ) 頁： 815 - 824   2018年8月

MIR-146A TARGETING SPLENIC MACROPHAGES PREVENTS SEPSIS-INDUCED MULTIPLE ORGAN INJURY INCLUDING ACUTE KIDNEY INJURY

Funahashi, Y; Kato, N; Kitai, H; Ishimoto, T; Kosugi, T; Tsuboi, N; Matsuda, N; Maruyama, S; Kadomatsu, K

SHOCK   49 巻 ( 6 ) 頁： 21 - 21   2018年6月

THE DURATION FROM THE RECOGNITION OF SHOCK TO THE INITIATION OF PMX-DHP IS A CRITICAL DETERMINANT OF SURVIVAL IN PATIENTS WITH SEPTIC SHOCK

Funahashi, Y; Kato, N; Ozeki, T; Kobayashi, A; Oishi, H; Maruyama, S

SHOCK   49 巻 ( 6 ) 頁： 68 - 68   2018年6月

INDUCTION OF IMMUNOSUPPRESSIVE MICRO-RNA IN SPLEEN ATTENUATES SEPSIS INDUCED ACUTE KIDNEY INJURY

Funahashi, Y; Kato, N; Ishimoto, T; Kosugi, T; Tsuboi, N; Kadomatsu, K; Maruyama, S

NEPHROLOGY DIALYSIS TRANSPLANTATION   32 巻   2017年5月

Growth Factor Midkine Promotes T-Cell Activation through Nuclear Factor of Activated T Cells Signaling and Th1 Cell Differentiation in Lupus Nephritis

Masuda, T; Maeda, K; Sato, W; Kosugi, T; Sato, Y; Kojima, H; Kato, N; Ishimoto, T; Tsuboi, N; Uchimura, K; Yuzawa, Y; Maruyama, S; Kadomatsu, K

AMERICAN JOURNAL OF PATHOLOGY   187 巻 ( 4 ) 頁： 740 - 751   2017年4月

A CASE OF RAPIDLY PROGRESSIVE NEPHRITIC SYNDROME AND NEPHROTIC SYNDROME DURING THE TREATMENT OF DERMATOMYOSITIS AND DIABETES

Sato, N; Katsuno, T; Mori, M; Saito, S; Kato, N; Ishimoto, T; Kosugi, T; Tsuboi, N; Ito, Y; Maruyama, S

RHEUMATOLOGY   56 巻   頁： 75 - 75   2017年3月

Single-dose Rituximab Therapy for Refractory Idiopathic Membranous Nephropathy: A Single-center Experience

Katsuno, T; Ozaki, T; Kim, H; Kato, N; Suzuki, Y; Akiyama, S; Ishimoto, T; Kosugi, T; Tsuboi, N; Ito, Y; Maruyama, S

INTERNAL MEDICINE   56 巻 ( 13 ) 頁： 1679 - 1686   2017年

Increase of Antimyeloperoxidase Antineutrophil Cytoplasmic Antibody (ANCA) in Patients with Renal ANCA-associated Vasculitis: Association with Risk to Relapse. 査読有り

J Rheumatol.     頁： 1853-60   2015年9月

CD147/basigin limits lupus nephritis and Th17 cell differentiation in mice by inhibiting the interleukin-6/STAT-3 pathway. 査読有り

Maeda K, Kosugi T, Sato W, Kojima H, Sato Y, Kamimura D, Kato N, Tsuboi N, Yuzawa Y, Matsuo S, Murakami M, Maruyama S, Kadomatsu K.

Arthritis Rheumatol.     頁： 2185-95   2015年5月

The efficacy of tolvaptan as a diuretic for chronic kidney disease patients. 査読有り

Tanaka A, Katsuno T, Ozaki T, Sakata F, Kato N, Suzuki Y, Kosugi T, Kato S, Tsuboi N, Sato W, Yasuda Y, Mizuno M, Ito Y, Matsuo S, Maruyama S.

Acta Cardiol.     頁： 217-23.   2015年4月

Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis. 査読有り

Melo SA, Sugimoto H, O'Connell JT, Kato N, Villanueva A, Vidal A, Qiu L, Vitkin E, Perelman LT, Melo CA, Lucci A, Ivan C, Calin GA, Kalluri R

Cancer Cell     頁： 707-21   2014年11月

CD147/basigin reflects renal dysfunction in patients with acute kidney injury. 査読有り

Nagaya H, Kosugi T, Maeda-Hori M, Maeda K, Sato Y, Kojima H, Hayashi H, Kato N, Ishimoto T, Sato W, Yuzawa Y, Matsuo S, Kadomatsu K, Maruyama S.

Clin Exp Nephrol.     頁： 746-54   2014年10月

TGF-β1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis. 査読有り

Borges FT, Melo SA, Özdemir BC, Kato N, Revuelta I, Miller CA, Gattone VH 2nd, LeBleu VS, Kalluri R.

J Am Soc Nephrol.     頁： 385-92.   2013年2月

Deficiency of growth factor midkine exacerbates necrotizing glomerular injuries in progressive glomerulonephritis. 査読有り

Kojima H, Kosugi T, Sato W, Sato Y, Maeda K, Kato N, Kato K, Inaba S, Ishimoto T, Tsuboi N, Matsuo S, Maruyama S, Yuzawa Y, Kadomatsu K.

Am J Pathol.     頁： 410-9   2013年2月

Basigin/CD147 promotes renal fibrosis after unilateral ureteral obstruction. 査読有り

Kato N, Kosugi T, Sato W, Ishimoto T, Kojima H, Sato Y, Sakamoto K, Maruyama S, Yuzawa Y, Matsuo S, Kadomatsu K.

Am J Pathol.     頁： 572-9.   2011年2月

The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion. 査読有り

Kato N, Yuzawa Y, Kosugi T, Hobo A, Sato W, Miwa Y, Sakamoto K, Matsuo S, Kadomatsu K.

J Am Soc Nephrol.     頁： 1565-76   2009年7月

The growth factor midkine regulates the renin-angiotensin system in mice. 査読有り

Hobo A, Yuzawa Y, Kosugi T, Kato N, Asai N, Sato W, Maruyama S, Ito Y, Kobori H, Ikematsu S, Nishiyama A, Matsuo S, Kadomatsu K.

J Clin Invest.     頁： 1616-25   2009年6月

Overexpression of calmodulin in pancreatic beta cells induces diabetic nephropathy. 査読有り

Yuzawa Y, Niki I, Kosugi T, Maruyama S, Yoshida F, Takeda M, Tagawa Y, Kaneko Y, Kimura T, Kato N, Yamamoto J, Sato W, Nakagawa T, Matsuo S.

J Am Soc Nephrol.     頁： 1701-11   2008年9月

Midkine is involved in tubulointerstitial inflammation associated with diabetic nephropathy. 査読有り

Kosugi T, Yuzawa Y, Sato W, Arata-Kawai H, Suzuki N, Kato N, Matsuo S, Kadomatsu K.

Lab Invest.     頁： 903-13   2007年9月

難治性腎疾患におけるCaMK4を介した新規ポドサイト特異的治療法の開発

研究課題/研究課題番号：19K08723  2019年4月 - 2022年3月

科学研究費助成事業  基盤研究(C)

前田 佳哉輔, 丸山 彰一, 古橋 和拡, 勝野 敬之, 小杉 智規, 加藤 規利

マイクロRNAと脂肪幹細胞由来エクソソームを用いた、敗血症性AKI治療開発

研究課題/研究課題番号：19K08676  2019年4月 - 2022年3月

科学研究費助成事業  基盤研究(C)

加藤 規利, 前田 佳哉輔, 丸山 彰一, 古橋 和拡, 勝野 敬之

敗血症患者の脾臓マクロファージをターゲットとした、新規核酸医薬開発

研究課題/研究課題番号：18K19562  2018年6月 - 2020年3月

挑戦的研究(萌芽)

安田 宜成

ExosomesとマイクロRNAを用いた、安全性の高いオーダーメイド治療の開発

研究課題/研究課題番号：16K09610  2016年4月 - 2019年3月

加藤 規利

心腎連関における細胞外小胞Exosomesの役割と、心予後予測因子の開発

2014年4月 - 2016年3月

科学研究費補助金  若手研究(B)