国立感染症研究所臨時職員

2005.4 - 2006.9

国立感染症研究所流動研究員

2004.4 - 2005.3

京都大学大学院医学研究科研修員

2002.4 - 2004.3

日本学術振興会特別研究員(DC1)

1999.4 - 2002.3

日本感染症学会   会員

2006.10

日本化学療法学会   会員

2006.12

日本小児感染症学会   会員

2007.7

日本周産期・新生児医学会   会員

2010.2

American Society for Microbiology   Contributing member

2005.9

The Lancefield Society   Standard member

2022.3

Bird's-eye MApping of plasmids (BeMAp) for visualization and comparison of genomic structures of different plasmids by mapping antimicrobial resistance genes on spreadsheets

Tsuda, Y; Suzuki, M; Wachino, JI; Kimura, K; Arakawa, Y

JOURNAL OF MICROBIOLOGICAL METHODS   Vol. 204   page： 106645   2023.1

Genomic Traits Associated with Virulence and Antimicrobial Resistance of Invasive Group B Streptococcus Isolates with Reduced Penicillin Susceptibility from Elderly Adults Reviewed

Koide, S; Nagano, Y; Takizawa, S; Sakaguchi, K; Soga, E; Hayashi, W; Tanabe, M; Denda, T; Kimura, K; Arakawa, Y; Nagano, N

MICROBIOLOGY SPECTRUM   Vol. 10 ( 3 ) page： e0056822   2022.6

Dissecting the clonality of I1 plasmids using ORF-based binarized structure network analysis of plasmids (OSNAp) Reviewed

Suzuki, M; Norizuki, C; Wachino, J; Kawamura, K; Nagano, N; Nagano, Y; Hayashi, W; Kimura, K; Doi, Y; Arakawa, Y

JOURNAL OF INFECTION AND CHEMOTHERAPY   Vol. 28 ( 4 ) page： 473 - 479   2022.4

Molecular Epidemiology of <i>Enterobacter cloacae</i> Complex Isolates with Reduced Carbapenem Susceptibility Recovered by Blood Culture Reviewed

Sarangi, J; Matsuo, N; Nonogaki, R; Hayashi, M; Kawamura, K; Suzuki, M; Jin, WC; Tamai, K; Ogawa, M; Wachino, J; Kimura, K; Yagi, T; Arakawa, Y

JAPANESE JOURNAL OF INFECTIOUS DISEASES   Vol. 75 ( 1 ) page： 41 - 48   2022.1

Isolation of Group A Streptococci with Reduced <i>In Vitro</i> β-Lactam Susceptibility Harboring Amino Acid Substitutions in Penicillin-Binding Proteins in Japan Reviewed

Ikeda, T; Suzuki, R; Jin, WC; Wachino, JI; Arakawa, Y; Kimura, K

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY   Vol. 65 ( 12 ) page： e0148221   2021.11

Practical Agar-Based Disk Diffusion Tests Using Sulfamoyl Heteroarylcarboxylic Acids for Identification of Subclass B1 Metallo-β-Lactamase-Producing <i>Enterobacterales</i> Reviewed

Norizuki, C; Wachino, J; Jin, WC; Kimura, K; Kawamura, K; Nagano, N; Arakawa, Y

JOURNAL OF CLINICAL MICROBIOLOGY   Vol. 59 ( 10 ) page： e0076121   2021.10

Daptomycin Susceptibility of Group B <i>Streptococcus</i> Reviewed

Ushino, T; Jin, W; Wachino, JI; Arakawa, Y; Kimura, K

JAPANESE JOURNAL OF INFECTIOUS DISEASES   Vol. 74 ( 3 ) page： 233 - 235   2021.5

Sulfamoyl Heteroarylcarboxylic Acids as Promising Metallo-β-Lactamase Inhibitors for Controlling Bacterial Carbapenem Resistance Reviewed

Wachino, J; Jin, WC; Kimura, K; Kurosaki, H; Sato, A; Arakawa, Y

MBIO   Vol. 11 ( 2 )   2020.3

Erythromycin-Susceptible but Clindamycin-Resistant Phenotype of Clinical ermB-PCR-Positive Group B Streptococci Isolates with IS1216E-Inserted ermB. Reviewed International coauthorship

Moroi H, Kimura K, Ido A, Banno H, Jin W, Wachino JI, Yamada K, Kikkawa F, Park YJ, Arakawa Y

Japanese journal of infectious diseases   Vol. 72 ( 6 ) page： 420 - 422   2019.11

4-Amino-2-Sulfanylbenzoic Acid as a Potent Subclass B3 Metallo-beta-Lactamase-Specific Inhibitor Applicable for Distinguishing Metallo-beta-Lactamase Subclasses Reviewed

Wachino Jun-ichi, Kanechi Reo, Nishino Erina, Mochizuki Marie, Jin Wanchun, Kimura Kouji, Kurosaki Hiromasa, Arakawa Yoshichika

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY   Vol. 63 ( 10 )   2019.10

Intercellular Transfer of Chromosomal Antimicrobial Resistance Genes between Acinetobacter baumannii Strains Mediated by Prophages Reviewed

Wachino Jun-ichi, Jin Wanchun, Kimura Kouji, Arakawa Yoshichika

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY   Vol. 63 ( 8 )   2019.8

Spread of seb-Positive Methicillin-Resistant Staphylococcus aureus SCCmec Type II-ST764 Among Elderly Japanese in Nonacute Care Settings Reviewed

Kawamura Kumiko, Kitaoka Kazuki, Kimura Kouji, Wachino Jun-ichi, Kondo Takaaki, Iinuma Yoshitsugu, Murakami Nobuo, Fujimoto Shuhei, Arakawa Yoshichika

MICROBIAL DRUG RESISTANCE   Vol. 25 ( 6 ) page： 915 - 924   2019.7

First Case in Korea of Group B Streptococcus With Reduced Penicillin Susceptibility Harboring Amino Acid Substitutions in Penicillin-Binding Protein 2X Reviewed International coauthorship

Yi Ahram, Kim Chang-Ki, Kimura Kouji, Arakawa Yoshichika, Hur Mina, Yun Yeo-Min, Moon Hee-Won

ANNALS OF LABORATORY MEDICINE   Vol. 39 ( 4 ) page： 414 - 416   2019.7

Relatively high rates of cefotaxime- and ceftriaxone-non-susceptible isolates among group B streptococci with reduced penicillin susceptibility (PRGBS) in Japan Reviewed

Kitamura Masaki, Kimura Kouji, Ido Ayaka, Seki Tomomi, Banno Hirotsugu, Jin Wanchun, Wachino Jun-ichi, Yamada Keiko, Arakawa Yoshichika

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY   Vol. 74 ( 4 ) page： 931 - 934   2019.4

Population-level transition of capsular polysaccharide types among sequence type 1 group B Streptococcus isolates with reduced penicillin susceptibility during a long-term hospital epidemic Reviewed

Nagano Noriyuki, Koide Shota, Hayashi Wataru, Taniguchi Yui, Tanaka Hayato, Maeyama Yoshihiko, Suzuki Masahiro, Kimura Kouji, Arakawa Yoshichika, Nagano Yukiko

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS   Vol. 53 ( 3 ) page： 203 - 210   2019.3

Potential effect of selective pressure with different beta-lactam molecules on the emergence of reduced susceptibility to beta-lactams in group B Streptococci Reviewed

Koide Shota, Hayashi Wataru, Taniguchi Yui, Tanaka Hayato, Kimura Kouji, Nagano Yukiko, Arakawa Yoshichika, Nagano Noriyuki

MICROBIOLOGY AND IMMUNOLOGY   Vol. 63 ( 2 ) page： 65 - 76   2019.2

Isolation of group B Streptococcus with reduced beta-lactam susceptibility from pregnant women Reviewed

Moroi Hiroaki, Kimura Kouji, Kotani Tomomi, Tsuda Hiroyuki, Banno Hirotsugu, Jin Wanchun, Wachino Jun-ichi, Yamada Keiko, Mitsui Takashi, Yamashita Mamoru, Kikkawa Fumitaka, Arakawa Yoshichika

EMERGING MICROBES & INFECTIONS   Vol. 8 ( 1 ) page： 2 - 7   2019.1

Prevalence of CTX-M-Type Extended-Spectrum -Lactamase-Producing Escherichia coli B2-O25-ST131 H30R Among Residents in Nonacute Care Facilities in Japan Reviewed

Kawamura Kumiko, Hayashi Kengo, Matsuo Nao, Kitaoka Kazuki, Kimura Kouji, Wachino Jun-ichi, Kondo Takaaki, Iinuma Yoshitsugu, Murakami Nobuo, Fujimoto Shuhei, Arakawa Yoshichika

MICROBIAL DRUG RESISTANCE   Vol. 24 ( 10 ) page： 1513 - 1520   2018.12

High prevalence of bla(CTX-M-14) among genetically diverse Escherichia coli recovered from retail raw chicken meat portions in Japan Reviewed

Hayashi Wataru, Ohsaki Yusuke, Taniguchi Yui, Koide Shota, Kawamura Kumiko, Suzuki Masahiro, Kimura Kouji, Wachino Jun-ichi, Nagano Yukiko, Arakawa Yoshichika, Nagano Noriyuki

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY   Vol. 284   page： 98 - 104   2018.11

A nationwide population-based surveillance of invasive Haemophilus influenzae diseases in children after the introduction of the Haemophilus influenzae type b vaccine in Japan. Reviewed

Suga S, Ishiwada N, Sasaki Y, Akeda H, Nishi J, Okada K, Fujieda M, Oda M, Asada K, Nakano T, Saitoh A, Hosoya M, Togashi T, Matsuoka M, Kimura K, Shibayama K

Vaccine   Vol. 36 ( 38 ) page： 5678 - 5684   2018.9

Carbapenem-Nonsusceptible <i>Haemophilus influenzae</i> with Penicillin-Binding Protein 3 Containing an Amino Acid Insertion Reviewed

Kitaoka, K; Kimura, K; Kitanaka, H; Banno, H; Jin, W; Wachino, J; Arakawa, Y

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY   Vol. 62 ( 8 )   2018.8

High isolation rate and multidrug resistance tendency of penicillin-susceptible group B <i>Streptococcus</i> with reduced ceftibuten susceptibility in Japan Reviewed

Banno, H; Kimura, K; Seki, T; Jin, WC; Wachino, J; Yamada, K; Nagano, N; Arakawa, Y

EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES   Vol. 37 ( 8 ) page： 1511 - 1519   2018.8

Predominance of Serogroup 19 CC320/271 among Penicillin-Nonsusceptible Streptococcus pneumoniae Isolates after Introduction of the PCV7 Vaccine in Several Regions of Japan Reviewed

Oodate Mitsuru, Kimura Kouji, Banno Hirotsugu, Yokoyama Satoru, Jin Wanchun, Wachino Jun-ichi, Hasegawa Yoshinori, Arakawa Yoshichika

JAPANESE JOURNAL OF INFECTIOUS DISEASES   Vol. 71 ( 1 ) page： 14 - 20   2018.1

Structural Insights into the TLA-3 Extended-Spectrum beta-Lactamase and Its Inhibition by Avibactarn and OP0595 Reviewed

Jin Wanchun, Wachino Jun-ichi, Yamaguchi Yoshihiro, Kimura Kouji, Kumar Anupriya, Yamada Mototsugu, Morinaka Akihiro, Sakamaki Yoshiaki, Yonezawa Minoru, Kurosaki Hiromasa, Arakawa Yoshichika

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY   Vol. 61 ( 10 )   2017.10

Analysis of multidrug resistant group B streptococci with reduced penicillin susceptibility forming small, less hemolytic colonies Reviewed

Banno Hirotsugu, Kimura Kouji, Tanaka Yosuke, Sekizuka Tsuyoshi, Kuroda Makoto, Jin Wanchun, Wachino Jun-ichi, Yamada Keiko, Shibayama Keigo, Arakawa Yoshichika

PLOS ONE   Vol. 12 ( 8 ) page： e0183453   2017.8

Specific bla(CTX-M-8)/IncI1 Plasmid Transfer among Genetically Diverse Escherichia coli Isolates between Humans and Chickens Reviewed

Norizuki Chihiro, Wachino Jun-ichi, Suzuki Masahiro, Kawamura Kumiko, Nagano Noriyuki, Kimura Kouji, Arakawa Yoshichika

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY   Vol. 61 ( 6 )   2017.6

High rate of slowly-killed-by-ampicillin phenotype among group B streptococci with reduced penicillin susceptibility Reviewed

Taniguchi Rina, Kimura Kouji, Miyazaki Akira, Banno Hirotsugu, Jin Wanchun, Yamada Keiko, Wachino Jun-ichi, Arakawa Yoshichika

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY   Vol. 72 ( 3 ) page： 941 - 942   2017.3

Structural insights into recognition of hydrolyzed carbapenems and inhibitors by subclass B3 metallo-β-lactamase SMB-1 Reviewed

J. Wachino, Y. Yamaguchi, S. Mori, W. Jin, K. Kimura, H. Kurosaki, Y. Arakawa

Antimicrobial Agents and Chemotherapy   Vol. 60 ( 7 ) page： 4274-82   2016

A highly macrolide-resistant Campylobacter jejuni strain with rare A2074T mutations in 23S rRNA genes Reviewed

H. Ohno, J. Wachino, R. Saito, W. Jin, K. Yamada, K. Kimura, Y. Arakawa

Antimicrobial Agents and Chemotherapy   Vol. 60 ( 4 ) page： 2580-1   2016

Effectual detection of group B streptococci with reduced penicillin susceptibility (PRGBS) by commercially available methicillin-resistant-Staphylococcus aureus (MRSA)-selective agar Reviewed

S. Fukigai¶, M. Morimoto¶, K. Kimura*, Y. Doyama, A. Miyazaki, C. Kamiya, H. Banno, E. Morishima, T. Onoda, N. Nagano, W. Jin, J. Wachino, K. Yamada, Y. Arakawa

Diagnostic Microbiology and Infectious Disease   Vol. 85 ( 3 ) page： 309-12   2016

In vitro reduction of antibacterial activity of tigecycline against multidrug-resistant Acinetobacter baumannii with host stress hormone norepinephrine Reviewed

M. Inaba, N. Matsuda, H. Banno, W. Jin, J. Wachino, K. Yamada, K. Kimura, Y. Arakawa

International Journal of Antimicrobial Agents     page： in press   2016

Comparative Analysis of Penicillin-Susceptible and Non-Susceptible Isolates in Group B Streptococci by Multilocus Sequence Typing Reviewed

R. Yamada, K. Kimura*, N. Nagano, Y. Nagano, S. Suzuki, W. Jin, J. Wachino, K. Yamada, K. Shibayama, Y. Arakawa

Japanese Journal of Infectious Diseases   Vol. 68 ( 4 ) page： 326-329   2015

Genetic Profiles of Fluoroquinolone-Nonsusceptible Klebsiella pneumoniae Among Cephalosporin-Resistant K. pneumoniae Reviewed

Y. Nagasaka, K. Kimura, K. Yamada, J. Wachino, W. Jin, S. Notake, H. Yanagisawa, Y. Arakawa

Microbial Drug Resistance   Vol. 21 ( 2 ) page： 224-33   2015

Have Group A Streptococci with Reduced Penicillin Susceptibility Emerged? Reviewed

T. Suzuki, K. Kimura*, H. Suzuki, H. Banno, W. Jin, J. Wachino, K. Yamada, Y. Arakawa

The Journal of Antimicrobial Chemotherapy   Vol. 70 ( 4 ) page： 1258-9   2015

New Plasmid-Mediated Aminoglycoside 6'-N-Acetyltransferase, AAC(6')-Ian, and Extended-Spectrum β-Lactamase, TLA-3, from Serratia marcescens Clinical Isolate Reviewed

W. Jin, J. Wachino, K. Kimura, K. Yamada, Y. Arakawa

The Journal of Antimicrobial Chemotherapy   Vol. 70 ( 5 ) page： 1331-7   2015

Classification of Group B Streptococci with Reduced β-Lactam Susceptibility (GBS-RBS) Based on the Amino Acid Substitutions in Penicillin-binding Proteins (PBPs) Reviewed

K. Kimura*, N. Nagano, Y. Arakawa

The Journal of Antimicrobial Chemotherapy   Vol. 70 ( 6 ) page： 1601-1603   2015

Molecular Epidemiological Characteristics of Klebsiella pneumoniae Associated with Bacteremia among Patients with Pneumonia Reviewed

R. Ito, Y. Shindo, D. Kobayashi, M. Ando, W. Jin, J. Wachino, K. Yamada, K. Kimura, T. Yagi, Y. Hasegawa, Y. Arakawa

Journal Clinical Microbiology   Vol. 53 ( 3 ) page： 879-86   2015

Ceftibuten-Containing Agar Plate for Detecting Group B Streptococci with Reduced Penicillin Susceptibility (PRGBS) Reviewed

C. Kamiya, K. Kimura*, Y. Doyama, A. Miyazaki, M. Morimoto, H. Banno, N. Nagano, W. Jin, J. Wachino, K. Yamada, Y. Arakawa

Diagnostic Microbiology and Infectious Disease   Vol. 82 ( 4 ) page： 269-273   2015

High isolation rate of multi-drug resistant group B streptococci with reduced penicillin susceptibility in Japan Reviewed

T. Seki, K. Kimura*, M. E. Reid, A. Miyazaki, H. Banno, W. Jin, J. Wachino, K. Yamada, Y. Arakawa

The Journal of Antimicrobial Chemotherapy   Vol. 70 ( 10 ) page： 2725-2728   2015

Characterization of piperacillin/tazobactam-resistant Klebsiella oxytoca recovered from a nosocomial outbreak Reviewed

A. Fujita, K. Kimura*, S. Yokoyama, W. Jin, J. Wachino, K. Yamada, H. Suematsu, Y. Yamagishi, H. Mikamo, Y. Arakawa

PLOS ONE   Vol. 10 ( 11 ) page： e0142366   2015

Characterization of Multi-drug-Resistant Group B Streptococci with Reduced Penicillin Susceptibility (PRGBS) Forming Small Non-β-hemolytic Colonies on Sheep Blood Agar Plates Reviewed

H. Banno, K. Kimura*, Y. Tanaka, H. Kitanaka, W. Jin, J. Wachino, K. Yamada, K. Shibayama, Y. Arakawa

Journal Clinical Microbiology   Vol. 52 ( 6 ) page： 2169-71   2014

Novel integron-mediated fosfomycin-resistance genetic determinant, fosK Reviewed

H. Kitanaka, J. Wachino, W. Jin, S. Yokoyama, M. Sasano, M. Hori, K. Yamada, K. Kimura, Y. Arakawa

Antimicrobial Agents and Chemotherapy   Vol. 58 ( 8 ) page： 4978-9   2014

Penicillin-susceptible group B streptococcal clinical isolates with reduced cephalosporin susceptibility Reviewed

N. Nagano, Y. Nagano, M. Toyama, K. Kimura, K. Shibayama, Y. Arakawa

Journal Clinical Microbiology   Vol. 52 ( 9 ) page： 3406-10   2014

Practical Agar-Based Disk Potentiation Test to Detect Fosfomycin-Non-Susceptible Escherichia coli Clinical Isolates Producing Glutathione S-Transferases. Reviewed

G. Nakamura, J. Wachino, N. Sato, K. Kimura, K. Yamada, W. Jin, K. Shibayama, T. Yagi, K. Kawamura, Y. Arakawa

Journal Clinical Microbiology   Vol. 52 ( 9 ) page： 3175-9   2014

Carbapenem-resistant Acinetobacter soli as a newly emerging invasive pathogen Reviewed

H. Kitanaka, M. Sasano, S. Yokoyama, M. Suzuki, W. Jin, M. Inayoshi, M. Hori, J. Wachino, K. Kimura, K. Yamada, Y. Arakawa

Emerging Infectious Disease   Vol. 20 ( 9 ) page： 1574-6   2014

Evaluation of Disk Potentiation Test Using KB Disks Containing High Dosage Fosfomycin and Glucose-6-Phosphate to Detect the Production of Glutathione S-Transferase Responsible For Fosfomycin Resistance Reviewed

J. Wachino, K. Kimura, K. Yamada, W. Jin, Y. Arakawa

Journal Clinical Microbiology   Vol. 52 ( 10 ) page： 3827-8   2014

The incidence of pediatric invasive Haemophilus influenzae and pneumococcal disease in Chiba prefecture, Japan before and after the introduction of conjugate vaccines Reviewed

N Ishiwada, H Hishiki, K Nagasawa, S Naito, Y Sato, B Chang, Y Sasaki, K Kimura, M Ohnishi, K Shibayama

Vaccine   Vol. 32 ( 42 ) page： 5425-31   2014

Screening for Group B Streptococci with Reduced Penicillin Susceptibility (PRGBS) in Clinical Isolates Obtained between 1977 and 2005 Reviewed

K. Kimura, Y. Nishiyama, S. Shimizu, J. Wachino, M. Matsui, S. Suzuki, K. Yamane, K. Shibayama, Y. Arakawa

Japanese Journal of Infectious Diseases   Vol. 66 ( 3 ) page： 222-225   2013

Rapid and reliable loop-mediated isothermal amplification method for detecting Streptococcus agalactiae Reviewed

K. Kimura, H. Yanagisawa, J. Wachino, K. Shibayama, Y. Arakawa

Japanese Journal of Infectious Diseases   Vol. 66   page： 546-548   2013

High Frequency of Fluoroquinolone- and Macrolide-resistant Streptococci among Clinically Isolated Group B Streptococci with Reduced Penicillin Susceptibility Reviewed

K. Kimura, N. Nagano, Y. Nagano, S. Suzuki, J. Wachino, K. Shibayama, Y. Arakawa

The Journal of Antimicrobial Chemotherapy   Vol. 68 ( 3 ) page： 539-42   2013

Ability of the VITEK® 2 System to Detect Group B Streptococci with Reduced Penicillin Susceptibility (PRGBS) Reviewed

K. Kimura, N. Nagano, Y. Nagano, J. Wachino, K. Shibayama, Y. Arakawa

The Journal of Antimicrobial Chemotherapy   Vol. 68 ( 6 ) page： 1442-4   2013

Active Screening of Group B Streptococci with Reduced Penicillin Susceptibility and Altered Serotype Distribution, Isolated from Pregnant Women in Kobe, Japan Reviewed

K. Kimura, K. Matsubara, G. Yamamoto, K. Shibayama, Y. Arakawa

Japanese Journal of Infectious Diseases   Vol. 66 ( 2 ) page： 158-60   2013

High cephalosporin resistance due to amino acid substitutions in PBP1A and PBP2X in a clinical isolate of group B streptococcus Reviewed

K. Kimura, J. Wachino, H. Kurokawa, M. Matsui, S. Suzuki, K. Yamane, N. Nagano, K. Shibayama, Y. Arakawa

The Journal of Antimicrobial Chemotherapy   Vol. 68 ( 7 ) page： 1533-1536   2013

Nosocomial spread of multidrug-resistant group B streptococci with reduced penicillin susceptibility belonging to clonal complex 1 Reviewed

N. Nagano, Y. Nagano, M. Toyama, K. Kimura, T. Tamura, K. Shibayama, Y. Arakawa

The Journal of Antimicrobial Chemotherapy   Vol. 67 ( 4 ) page： 849-856   2012

Predominance of sequence type 1 group with serotype VI among group B atreptococci with reduced penicillin susceptibility identified in Japan Reviewed

K. Kimura, N. Nagano, Y. Nagano, J. Wachino, S. Suzuki, K. Shibayama, Y. Arakawa

The Journal of Antimicrobial Chemotherapy   Vol. 66   page： 2460-2464   2011

Prevalence of Fosfomycin Resistance among CTX-M-Producing Escherichia coli Clinical Isolates in Japan and Identification of Novel Plasmid-Mediated Fosfomycin-Modifying Enzymes Reviewed

J. Wachino, K. Yamane, S. Suzuki, K. Kimura, Y. Arakawa

Antimicrobial Agents and Chemotherapy   Vol. 54 ( 7 ) page： 3061-3064   2010

RmtC introduces G1405 methylation in 16S rRNA and confers high-level aminoglycoside resistance on Gram-positive microorganisms Reviewed

J. Wachino, K. Shibayama, K. Kimura, K. Yamane, S. Suzuki, Y. Arakawa

FEMS Microbiol Lett   Vol. 311 ( 1 ) page： 56-60   2010

Molecular characterization of group B streptococci with reduced penicillin susceptibility recurrently isolated from a sacral decubitus ulcer Reviewed

N. Nagano, K. Kimura, Y. Nagano, H. Yakumaru, Y. Arakawa

The Journal of Antimicrobial Chemotherapy   Vol. 64 ( 6 ) page： 1326-1328   2009

Practical disk diffusion test for detecting group B streptococcus with reduced penicillin susceptibility Reviewed

K. Kimura, J. Wachino, H. Kurokawa, S. Suzuki, K. Yamane, N. Shibata, Y. Arakawa

Journal Clinical Microbiology   Vol. 47 ( 12 ) page： 4154-4157   2009

First Molecular Characterization of Group B Streptococci with Reduced Penicillin Susceptibility Reviewed

K. Kimura, S. Suzuki, J. Wachino, H. Kurokawa, K. Yamane, N. Shibata, N. Nagano, H. Kato, K. Shibayama,, Y. Arakawa

Antimicrobial Agents and Chemotherapy   Vol. 52   page： 2890-2897   2008

Genetic heterogeneity in pbp genes among clinically isolated group B streptococci with reduced penicillin susceptibility Reviewed

N. Nagano, Y. Nagano, K. Kimura, K. Tamai, H. Yanagisawa, Y. Arakawa

Antimicrobial Agents and Chemotherapy   Vol. 52   page： 4258-4267   2008

New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate Reviewed

K. Yamane, J. Wachino, S. Suzuki, K. Kimura, N. Shibata, H. Kato, K. Shibayama, T. Konda, Y. Arakawa

Antimicrobial Agents and Chemotherapy   Vol. 51 ( 9 ) page： 3354-336   2007

Novel Plasmid-Mediated 16S rRNA m1A1408 Methyltransferase, NpmA, Found in a Clinically Isolated Escherichia coli Strain Resistant to Structurally Diverse Aminoglycosides Reviewed

J. Wachino, K. Shibayama, H. Kurokawa, K. Kimura, K. Yamane, S. Suzuki, N. Shibata, Y. Ike, Y. Arakawa

Antimicrobial Agents and Chemotherapy   Vol. 51 ( 12 ) page： 4401-4409   2007

16S rRNA methylase-producing, gram-negative pathogens, Japan Reviewed

K. Yamane, J. Wachino, S. Suzuki, N. Shibata, H. Kato, K. Shibayama, K. Kimura, K. Kai, S. Ishikawa, Y. Ozawa, T. Konda, Y. Arakawa

Emerging Infectious Disease   Vol. 13 ( 4 ) page： 642-646   2007

PCR Classification of CTX-M Type beta-Lactamase Genes Identified In Clinically Isolated Gram-Negative Bacilli in Japan Reviewed

N. Shibata, H. Kurokawa, Y. Doi, T. Yagi, K. Yamane, J. Wachino, S. Suzuki, K. Kimura, S. Ishikawa, H. Kato, Y. Ozawa, K. Shibayama, K. Kai, T. Konda, Y. Arakawa

Antimicrobial Agents and Chemotherapy   Vol. 50   page： 791-795   2006

Mode of transposition and expression of 16S rRNA methyltransferase gene rmtC accompanied by ISEcp1 Reviewed

J. Wachino, K. Yamane, K. Kimura N. Shibata, S. Suzuki Y. Ike Y. Arakawa

Antimicrobial Agents and Chemotherapy   Vol. 50   page： 3212-3215   2006

Novel Plasmid-Mediated 16S rRNA Methylase, RmtC, Found in Proteus mirabilis Demonstrating Extraordinary High-Level Resistance against Various Aminoglycoside Reviewed

J. Wachino, K. Yamane, K. Shibayama, H. Kurokawa, N. Shibata, S. Suzuki, Y. Doi, K. Kimura, Y. Ike, Y. Arakawa

Antimicrobial Agents and Chemotherapy   Vol. 50   page： 178-184   2006

Horizontal Transfer of blaCMY-Bearing Plasmids among Clinical Escherichia coli and Klebsiella pneumoniae Isolates, and Emergence of Cefepime-Hydrolyzing CMY-19 Reviewed

J. Wachino, H. Kurokawa, S. Suzuki, K. Yamane, N. Shibata, K. Kimura, Y. Ike, Y. Arakawa

Antimicrobial Agents and Chemotherapy   Vol. 50   page： 534-541   2006

Hyperpolarization-activated, cyclic nucleotide-gated HCN2 cation channel forms a protein assembly with multiple neuronal scaffold proteins in distinct modes of protein-protein interaction Reviewed

K. Kimura, J. Kitano, Y. Nakajima, S. Nakanishi

Genes to Cells   Vol. 9   page： 631-640   2004

Tamalin Is a Scaffold Protein That Interacts with Multiple Neuronal Proteins in Distinct Modes of Protein-Protein Association Reviewed

J. Kitano, Y. Yamazaki, K. Kimura, T. Masukado, Y. Nakajima, S. Nakanishi

The Journal of Biological Chemistry   Vol. 278   page： 14762-14768   2003

Tamalin, a PDZ Domain-Containing Protein, Links a Protein Complex Formation of Group 1 Metabotropic Glutamate Receptors and the Guanine Nucleotide Exchange Factor Cytohesins Reviewed

J. Kitano, K. Kimura, Y. Yamazaki, T. Soda, R. Shigemoto, Y. Nakajima, S. Nakanishi

The Journal of Neuroscience   Vol. 22   page： 1280-1289   2002

Molecular Aspects of High-Level Resistance to Sulbactam-Cefoperazone in Klebsiella oxytoca Clinical Isolates Reviewed

K. Kimura, Y. Arakawa, S. Ohsuka, H. Ito, K. Suzuki, H. Kurokawa, N. Kato, M. Ohta

Antimicrobial Agents and Chemotherapy   Vol. 40   page： 1988-1994   1996

Group B Streptococcus with reduced beta-lactam susceptibility (GBS-RBS) Invited

K. Kimura, N. Nagano, Y. Arakawa

PRGBSを含むβラクタム系薬低感受性B群レンサ球菌(GBS-RBS)に関する研究

木村幸司、長野則之、荒川宜親

第89回日本細菌学会総会 

侵襲性B群レンサ球菌感染症に関する現状と課題

木村幸司

第89回日本細菌学会総会 

ペニシリン低感受性B群連鎖球菌(Group B Streptococci with reduced penicillin susceptibility, PRGBS)研究

木村幸司

第52回日本細菌学会中部支部総会 

ペニシリン低感受性B群連鎖球菌(PRGBS)に関する最新知見 International conference

木村幸司、長野則之、長野由紀子、外山雅美、荒川宜親

第87回日本感染症学会学術講演会、第61回日本化学療法学会総会　合同学会 

連鎖球菌感染症にみられる新しい知見

木村幸司、長野則之、長野由紀子、外山雅美、荒川宜親

第61回日本感染症学会東日本地方会学術集会、第59回日本化学療法学会東日本支部総会、合同学会 

ペニシリン低感受性B群連鎖球菌の最新の知見

木村幸司、長野則之、長野由起子、荒川宜親

第58回日本化学療法学会 

ペニシリン低感受性B群連鎖球菌(PRGBS)の遺伝学的背景に関する解析 International conference

木村幸司、長野則之、長野由紀子、荒川宜親

第83回日本細菌学会 

ペニシリン低感受性B群連鎖球菌に関する依頼解析

木村幸司、和知野純一、鈴木里和、山根一和、柴田尚宏、荒川宜親

第82回日本細菌学会 

ペニシリン耐性B群連鎖球菌の出現と耐性機構解析

木村幸司、鈴木里和、山根一和、柴田尚宏、荒川宜親

第81回日本感染症学会総会 

多剤耐性菌出現機構の解明に向けた研究

2012.11

2012年度　武田科学振興財団　医学系研究奨励（感染症） 

Characterization of IMP-1, a major carbapenem resistance factor in bacteria

Grant number：15H04868  2015.4 - 2018.3

Arakawa Yoshichika

神経回路網形成における代謝型グルタミン酸受容体の役割

1999.4 - 2002.3

科学研究費補助金 

大学院ベーシックトレーニング

2022

基礎医学セミナー

2022

生体と微生物

2022

基礎医学セミナー

2021

ベーシックトレーニング

2021

生体と微生物

2021

自然環境と人間

2021

修士必須科目講義

2021

ベーシックトレーニング

2020

基礎医学セミナー

2020

修士必須科目講義

2020

生体と微生物

2020