Updated on 2024/03/11

写真a

 
OHNO, Tamio
 
Organization
Graduate School of Medicine Center for Research of Laboratory Animals and Medical Research Engineering Division for Research of Laboratory Animals Associate professor
Graduate School
Graduate School of Medicine
Undergraduate School
School of Medicine
Title
Associate professor
Contact information
メールアドレス

Degree 1

  1. 博士(農学) ( 1995.3   名古屋大学 ) 

Research Interests 1

  1. mouse, forward genetics, susceptibility gene, diabetes, parasite, malaria, cestode

Research Areas 2

  1. Others / Others  / 寄生虫学

  2. Others / Others  / 実験動物学

Current Research Project and SDGs 2

  1. Genetic analysis of host resistance to malarial infection in mice

  2. マウスの体系的遺伝解析系を用いた多因子遺伝形質の解析

Research History 8

  1. 名古屋大学大学院医学系研究科附属医学教育研究支援センター実験動物部門 准教授

    2007.4

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    Country:Japan

  2. Nagoya University

    2005.11

  3. 名古屋大学大学院医学系研究科附属医学教育研究支援センター 実験動物部門 助教授

    2005.7 - 2007.3

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    Country:Japan

  4. 名古屋大学大学院医学系研究科附属医学教育研究支援センター 実験動物部門 助手

    2004.5 - 2005.6

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    Country:Japan

  5. 名古屋大学大学院医学系研究科附属動物実験施設 助手

    2001.4 - 2004.4

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    Country:Japan

  6. 名古屋大学大学院医学系研究科附属動物実験施設・助手

    1999.9 - 2001.3

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    Country:Japan

  7. 浜松医科大学寄生虫学講座・助手

    1997.6 - 1999.8

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    Country:Japan

  8. 長寿科学振興財団・リサーチレジデント

    1995.4 - 1997.5

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    Country:Japan

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Education 3

  1. Nagoya University   Graduate School, Division of Agriculture

    1992.4 - 1995.3

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    Country: Japan

  2. Nagoya University   Graduate School, Division of Agriculture

    1990.4 - 1992.3

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    Country: Japan

  3. Nagoya University   Faculty of Agriculture

    1986.4 - 1990.3

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    Country: Japan

Professional Memberships 12

  1. 日本実験動物学会   評議員

    2014.5

  2. 日本寄生虫学会   評議員

    2008.4

  3. 日本実験動物学会    編集委員会委員

    2014.5

  4. 日本寄生虫学会   学術委員会委員

    2006.4

  5. 日本実験動物学会   定款・細則・規程等検討委員会

    2018.5

  6. 日本糖尿病・肥満動物学会

  7. 日本臨床寄生虫学会

  8. 関西実験動物研究会   評議員

    2009.4

  9. 日本実験動物学会   評議員

    2006.6 - 2012.5

  10. 日本実験動物学会   広報渉外委員会委員

    2006.6 - 2008.5

  11. 日本実験動物学会   教育研修ワーキンググループ委員

    2006.6 - 2008.5

  12. 日本実験動物学会   実験動物使用数調査ワーキンググループ

    2010.6 - 2012.5

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Committee Memberships 8

  1. 国立大学法人動物実験施設協議会・組織委員会   委員  

    2020.6   

  2. 名古屋医工連携インキュベータ安全衛生管理委員会   委員  

    2010.4   

  3. 国立大学法人動物実験施設協議会・バイオセイフティ委員会   委員  

    2006.6 - 2022.5   

  4. 国立大学医学部長会議・動物実験に関する小委員会   委員  

    2009.7 - 2012.6   

  5. 国立大学法人動物実験施設協議会・動物実験適正化委員会   委員  

    2014.6 - 2020.5   

  6. 国立大学法人動物実験施設協議会・中型動物委員会   委員  

    2010.6 - 2012.5   

  7. 国立大学法人動物実験施設協議会・中型動物委員会   委員  

    2006.6 - 2008.5   

  8. 国立大学法人動物実験施設協議会・学術情報広報委員会   委員  

    2006.6 - 2010.5   

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Awards 1

  1. 平成16年度日本実験動物学会奨励賞

    2005.5   日本実験動物学会  

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Papers 82

  1. Inheritance and breeding of the waltzing mutant in the musk shrew (Suncus murinus, Insectivora) characterized by the circling and head-shaking behaviors. Reviewed

    Ohno T, Ishikawa A, Yamagata T, Namikawa T, Tomita T

    Exp. Anim.   Vol. 41 ( 2 ) page: 123-129   1992

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  2. Red-eyed dilution (rd), a novel coat-color mutant gene in the musk shrew (Suncus murinus, Insectivora). Reviewed

    Ohno T, Oda S, Yamagata T, Namikawa T

    Exp. Anim.   Vol. 41 ( 2 ) page: 173-179   1992

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  3. TESS line: a laboratory line of the musk shrew (Suncus murinus, Insectivora), triple-homozygous for the curly hair (ch), cream coat-color (cr) and red-eyed dilution (rd) genes and segregating the sucrase deficients (suc/suc). Reviewed

    Ohno T, Oda S, Namikawa T

    Exp. Anim.   Vol. 43 ( 1 ) page: 111-113   1994

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  4. Development of a laboratory colony of the musk shrew (Suncus murinus, Insectivora) exhibiting a high incidence of spontsneous diabetes. Reviewed

    Ohno T, Namikawa T

    Lab. Anim. Sci.   Vol. 46 ( 1 ) page: 107-108   1996

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  5. 糖尿病スンクス:EDS(early-onset diabetes in suncus)系統. Invited

    大野民生、吉田太、並河鷹夫

    日本臨床   Vol. 56 ( 1998年増刊 ) page: 704-707   1998

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    Authorship:Lead author   Language:Japanese  

  6. Serotonergic neurons are present and innervate blood vessels in the olfactory bulb of the laboratory shrew, Suncus murinus. Reviewed

    Won M H, Ohno T, Suh J G, Lee J C, Jo S M, Oh Y S, Namikawa T, Kitoh J

    Neurosci. Let.   Vol. 243 ( 1-3 ) page: 53-56   1998

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  7. Toxin-induced IDDM (Insulin Dependent Diabetes Mellitus) in the musk shrew. Reviewed

    Ohno T, Kitoh J, Yamashita K, Ichikawa Y, Horio F, Terada M, Tanaka S, Namikawa T

    Life Sci.   Vol. 63 ( 6 ) page: 455-462   1998

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  8. A new spontaneous animal model of NIDDM without obesity in the musk shrew. Reviewed

    Ohno T, Yoshida F, Ichikawa Y, Matsuo S, Hotta N, Terada M, Tanaka S Yamashita K, Namikawa T, Kitoh J

    Life Sci.   Vol. 62 ( 11 ) page: 995-1006   1998

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  9. Delayed development of reflexes and hyperactive locomotion in the spontaneous mutant "waltzing" of the musk shrew, Suncus murinus. Reviewed

    Matsuura A, Ohno T, Matsushima T, Namikawa T, Ishikawa A

    Exp. Anim.   Vol. 48 ( 3 ) page: 191-197   1999

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  10. Establishment of an aging farm of F344/N rats and C57BL/6 mice at National Institute for Longevity Scinences (NILS) Reviewed

    Tanaka S, Segawa N, Tamaya N, Ohno T

    Arch. Gerontol. Geriat.   Vol. 30 ( 3 ) page: 215-223   2000

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  11. Distribution of body weight , blood insulin and lipids levels in the SMXA recombinant inbred strains and the QTL analysis Reviewed

    Anunciado R V P, Ohno T, Mori M, Ishikawa A, Tanaka S, Horio F, Nishimura M, Namikawa T

    Exp. Anim.   Vol. 49 ( 3 ) page: 217-224   2000

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  12. Characterization of hyperinsulinemic recombinant inbred (RI) strains SMXA-5 and SMXA-9) derived from normoinsulinemic SM/J and A/J mice Reviewed

    Anunciado R V P, Horio F, Ohno T, Tanaka S, Nishimura M, Namikawa T

    Exp. Anim.   Vol. 49 ( 2 ) page: 83-90   2000

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  13. Developing a new model for non-insulin dependent diabetes mellitus (NIDDM) by using Philippine wild mouse, Mus musculus castaneus Reviewed

    Anunciado R V P, Imamura T, Ohno T, Horio F, Namikawa T

    Exp. Anim.   Vol. 49 ( 1 ) page: 1-8   2000

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  14. Genetic analysis of mortality in murine angiostrongyliasis costaricensis using SMXA recombinant inbred mouse strains Reviewed

    Ishih A, Ohno T, Nishimura M, Terada M

    Parasitol. Int.   Vol. 49 ( 4 ) page: 335-338   2000

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  15. Fatty liver and hyperlipidemia in IDDM (insulin dependent diabetes mellitus) of streptozotocin-treated shrews Reviewed

    Ohno T, Horio F, Tanaka S, Terada M, Namikawa T, Kitoh J

    Life Sci.   Vol. 66 ( 2 ) page: 125-131   2000

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  16. Adrenal glands in smallsmooth-tailed tree shrew Reviewed

    Tanaka S. Miyaishi O, Tamaya N, Ohno T, Yamada J

    Exp. Anim.   Vol. 50 ( 5 ) page: 451-454   2001

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  17. A group of five parameters as a new biological marker on F344/N rats Reviewed

    Tanaka S, Segawa T, Tamaya N, Miyaishi O, Ohno T

    Arch. Gerontol. Geriat.   Vol. 32 ( 2 ) page: 139-150   2001

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  18. Quantitative trait loci for body weight in the intercross between the SM/J and A/J mice Reviewed

    Anunciado R V P, Nishimura M, Mori M, Ishikawa A, Tanaka S, Horio F, Ohno T, Namikawa T

    Exp. Anim.   Vol. 50 ( 4 ) page: 319-324   2001

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  19. Diabetic cataract of the musk shrew (Suncus murinus, Insectivora) exhibiting spontaneous non-insulin dependent diabetes mellitus (NIDDM) Reviewed

    Ohno T, Kitoh J, Tanaka S, Nishimura M, Namikawa T

    Exp. Anim.   Vol. 50 ( 5 ) page: 431-433   2001

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  20. Blood and liver lipid concentrations in EDS shrews exhibiting spontaneous non-insulin dependent diabetes mellitus (NIDDM) Reviewed

    Ohno T, Horio F, Kitoh J, Tanaka S, Nishimura M, Namikawa T

    Exp. Anim.   Vol. 50 ( 5 ) page: 427-429   2001

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  21. Chromosomal mapping of the host resistance locus to rodent malaria (Plasmodium yoelii) infection in mice Reviewed

    Ohno T, Ishih A, Kohara Y, Yonekawa H, Terada M, Nishimura M

    Immunogenetics   Vol. 53 ( 9 ) page: 736-740   2001

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  22. Survival curve modified through dietary restriction (DR) in male Donryu rats Reviewed

    Tanaka S, Ohno T, Miyaishi O, Itoh Y

    Arch. Gerontol. Geriat.   Vol. 35   page: 171-178   2002

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  23. Difference in average survival between F344/Du and F344/N rats is not due to genetic contamination Reviewed

    Tanaka S, Shito A, Tamaya N, Miyaishi O, Nishimura M, Ohno T

    Arch. Gerontol. Geriat.   Vol. 34 ( 1 ) page: 925-929   2002

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  24. Mouse H2 haplotype influences on survival rate after Angiostrongylus costaricensis infection Reviewed

    Ohno T, Ishih A, Wakana S, Nishimura M, Terada M

    Exp. Parasitol.   Vol. 100 ( 2 ) page: 140-142   2002

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  25. Chromosomal mapping of host susceptibility loci to Angiostrongylus costaricensis nematode infection in mice Reviewed

    Ohno T, Ishih A, Tanaka S, Nishimura M, Terada M

    Immunogenetics   Vol. 53 ( 10-11 ) page: 925-929   2002

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  26. Quantitative trait locus analysis of serum insulin, triglyceride, total cholesterol and phospholipid levels in the (SM/J × A/J)F2 mice. Reviewed

    Anunciado R V P, Nishimura M, Mori M, Ishikawa A, Tanaka S, Horio F, Ohno T, Namikawa T

    Exp. Anim.   Vol. 52 ( 1 ) page: 37-42   2003

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  27. Combinations of non-diabetic parental genomes elict impaired glucose tolerance in mouse SMXA RI strains. Reviewed

    Kobayashi M, Ohno T, Tsuji A, Nishimura M, Horio F

    Diabetes   Vol. 52 ( 1 ) page: 180-186   2003

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  28. Improved strain distribution patterns of SMXA recombinant inbred strains by microsatellite markers. Reviewed

    Ohno T, Katoh J, Kikkawa Y, Yonekawa H, Nishimura M

    Exp Anim   Vol. 52 ( 5 ) page: 415-417   2003

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  29. Detection of a new cerebral malaria susceptibility locus using CBA mice. Reviewed

    Ohno T, Nishimura M

    Immunogenetics   Vol. 56 ( 9 ) page: 675-678   2004

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  30. SMXA-5 mouse is a diabetic model susceptible to feeding a high-fat diet. Reviewed

    Kobayashi M, Io F, Kawai T, Nishimura M, Ohno T, Horio F

    Biosci Biotechnol Biochem   Vol. 68 ( 1 ) page: 226-230   2004

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  31. Characterization of diabetes-related traits in MSM and JF1 mice on high-fat diet. Reviewed

    Kobayashi M, Ohno T, Tsuchiya T, Horio F

    J Nutr Biochem   Vol. 15 ( 10 ) page: 614-621   2004

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  32. Fas has a role in cerebral malaria, but not in proliferation or exclusion of the murine parasite in mice. Reviewed

    Ohno T, Kobayashi F, Nishimura M

    Immunogenetics   Vol. 57 ( 3-4 ) page: 293-296   2005

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  33. Susceptibility to streptozotocin-induced diabetes is mapped to mouse chromosome 11. Reviewed

    Babaya N, Ikegami H, Fujisawa T, Nojima K, Itoi-Babaya M, Inoue K, Ohno T, Shibata M, Ogihara T

    Biochem Biophys Res Commun   Vol. 328 ( 1 ) page: 158-164   2005

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  34. Major quantitative trait locus on chromosome 2 for glucose tolerance in diabetic SMXA-5 mouse established from nondiabetic SM/J and A/J strains. Reviewed

    Kobayashi M, Io F, Kawai T, Kumazawa M,Ikegami H, Nishimura M, Ohno T, Horio F

    Diabetologia   Vol. 49 ( 3 ) page: 486-495   2006

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  35. Serum adiponectin concentration: its correlation with diabetes-related taraits and quantitative tarit loci analysis in mouse SMXA recombinant inbred strains. Reviewed

    Kobayashi M, Ohno T, Kawada Teruo, Ikegami H, Nishimura M, Horio F

    Biosci Biotechnol Biochem   Vol. 70 ( 3 ) page: 677-683   2006

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  36. Genetic association of mutation at agouti locus with adrenal X zone morphology in BALB/c mice. Reviewed

    TanakaS, Kuwahara S, Nishijima K, Ohno T, Matsuzawa A

    Exp Anim   Vol. 55 ( 4 ) page: 343-347   2006

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  37. Comparison of rat mandible bone characteristics in F344 sunstrains, F344/Du and F344/N. Reviewed

    TanakaS, Kuwahara S, Nishijima K, Ohno T, Nagaya M, Nakamura Y, Sumi Y, Miyaishi O, Aoyama H, Goto N

    Exp Anim   Vol. 55 ( 5 ) page: 415-418   2006

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  38. Morphometric comparison of the rat mandible in F344 sunstrains, F344/Du and F344/N. Reviewed

    TanakaS, Kuwahara S, Nishijima K, Nakamura Y, Sumi Y, Ohno T, Goto N

    Exp Anim   Vol. 55 ( 5 ) page: 433-438   2006

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  39. Novel hairless RET-transgenic mouse line with melanocytic nevi and anagen hair follicles. Reviewed

    Kato M, Takeda K, Kawamoto Y, Tsuzuki T, Kato Y, Ohno T, Hossain K, Iftakhar-E-Khuda I, Ohgami N, Isobe K, Takahashi M, Nakashima I

    J Invest Dermatol   Vol. 126 ( 11 ) page: 2547-2550   2006

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  40. Changes of estrous cycles with aging in female F344/n rats. Reviewed

    Sone K, Yamamoto-Sawamura T, Kuwahara S, Nishijima K, Ohno T, Aoyama H, Tanaka S

    Exp Anim   Vol. 56 ( 2 ) page: 139-148   2007

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  41. Occlusal tooth wear in female F344/N rats with aging. Reviewed

    Nishijima K, Kuwahara S, Ohno T, Miyaishi O, Ito Y, Sumi Y, Tanaka S.

    Arch Oral Biol   Vol. 52 ( 9 ) page: 844-849   2007

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  42. Searching for genetic factors of fatty liver in SMXA-5 mice by quantitative trait loci analysis under a high-fat diet. Reviewed

    Kumazawa M, Kobayashi M, Io F, Kawai T, Nishimura M, Ohno T, Horio F

    J Lipid Res   Vol. 48 ( 9 ) page: 2039-2046   2007

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  43. Mapping of jog locus to the region between D6Mit104 and D6Mit336 on mouse chromosome 6. Reviewed

    Sun X, Chen Z, Kanou Y, Takagishi Y, Hayashi Y, Ohno T, Murata Y, Oda S

    Exp Anim   Vol. 56 ( 5 ) page: 389-392   2007

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  44. Natural dental caries in molars of osteogenic disorder Shionogi rats. Reviewed

    Nishijima K, Kuwahara S, Ohno T, Miyaishi O, Ito Y, Makino S, Sumi Y, Tanaka S

    Comp Med   Vol. 57 ( 6 ) page: 590-593   2007

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  45. Quantitative trait loci for impaired glucose tolerance in nondiabetic SM/J and A/J mice. Reviewed

    Hada N, Kobayashi M, Fujiyoshi M, Ishikawa A, Kuga M, Nishimura M, Ebihara S, Ohno T, Horio F

    Physiol Genomics   Vol. 35 ( 1 ) page: 65-74   2008

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  46. Body and major organ weights of A/J-Chr 11SM consomic mice. Reviewed

    Tanaka S, Mizorogi T, Nishijima K, Kuwahara S, Tsujio M, Aoyama H, Taguchi C, Kobayashi M, Horio F, Ohno T

    Exp Anim   Vol. 58 ( 4 ) page: 357-361   2009

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  47. Confirmation of diabetes-related quantitative trait loci derived from SM/J and A/J mice by using congenic strains fed a high-carbohydrate or high-fat diet. Reviewed

    Kobayashi M, Hada N, Hoshino H, Ozawa T, Umeshita K, Nishimura M, Murai A, Ohno T, Horio F

    J Nutr Sci Vitaminol   Vol. 55 ( 3 ) page: 257-263   2009

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  48. A morphometric study of the adrenal cortex of the female DDD mouse. Reviewed

    Tsujio M, Mizorogi T, Nishijima K, Kuwahara S, Aoyama H, Ohno T, Tanaka S

    J Vet Med Sci   Vol. 71 ( 2 ) page: 183-187   2009

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  49. Occlusal tooth wear in male F344/N rats with aging. Reviewed

    Nishijima K, Kuwahara S, Ohno T, Miyaishi O, Ito Y, Sumi Y, Tanaka S

    Arch Gerontol Geriatr   Vol. 48 ( 2 ) page: 178-181   2009

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  50. Bone mineral analysis through dual energy X-ray absorptiometry in laboratory animals. Reviewed

    Tsujio M, Mizorogi T, Kitamura I, Maeda Y, Nishijima K, Kuwahara S, Ohno T, Niida S, Nagaya M, Saito R, Tanaka S

    J Vet Med Sci   Vol. 71 ( 11 ) page: 1493-1497   2009

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  51. A novel mouse model for de novo melanoma. Reviewed

    Kumasaka MY, Yajima I, Hossain K, Iida M, Tsuzuki T, Ohno T, Takahashi M, KatoM

    Cancer Res   Vol. 70 ( 1 ) page: 24-29   2010

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  52. Aging change of mandibular condyle in female F344/N rats. Reviewed

      Vol. 51   page: e11-e15   2010

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  53. Genetic analysis of abdominal fat distribution in SM/J and A/J mice. Reviewed

    Kobayashi M, Ohno T, Hada N, Fujiyoshi M, Kuga M, Nishimura M, Murai A, Horio F

    J Lipid Res   Vol. 51 ( 12 ) page: 3463-3469   2010.12

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  54. Life span of common marmoset (Callithrix jacchus) at CLEA Japan breeding colony. Reviewed

    Nishijima K, Saitoh R, Tanaka S, Ohsato-Suzuki M, Ohno T, Kitajima S

    Biogerontology   Vol. 13 ( 4 ) page: 439-443   2012

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  55. Establishment of consomic strains derived from A/J and SM/J mice for genetic analysis of complex traits. Reviewed

    Ohno T, Hata K, Baba T, Io F, Kobayashi M, Horio F, Nishimura M

    Mamm Genome   Vol. 23 ( 11-12 ) page: 764-769   2012.12

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  56. Detection of loci for allergic asthma using SMXA recombinant inbred strains of mice. Reviewed

    Ohno T, Okamoto M, Hara T,Hashimoto N, Imaizumi K, Matsushima M, Nishimura M, Shimokata K, Hasegawa Y, Kawabe T

    Immunogenetics   Vol. 65 ( 1 ) page: 17-24   2013.1

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  57. Populations of follicles in F344/N rats during aging. Reviewed

    Nishijima K, Tanaka S, Sakamoto SH, Kuwahara S, Ohno T, Kitajima S

    Reprod Biol   Vol. 13 ( 2 ) page: 145-149   2013.3

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  58. Toxoplasma gondii tachyzoite-infected peripheral blood mononuclear cells are enriched in mouse lungs and liver. Reviewed

    Unno A, Kachi S, Batanova TA, Ohno T, Elhawary N, Kitoh K, Takashima Y

      Vol. 134 ( 2 ) page: 160-164   2013.4

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  59. CD44 mediated hyaluronan adhesion of Toxoplasma gondii-infected leukocytes. Reviewed

    Hayashi T, Unno A, Baba M, Ohno T, Kitoh K, Takashima Y

    Parasitol Int   Vol. 63 ( 2 ) page: 479-484   2014.4

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  60. Searching for genomic region of high-fat diet-induced type 2 diabetes in mouse chromosome 2 by analysis of congenic strains. Reviewed

    Kobayashi M, Ohno T, Ihara K, Murai A, Kumazawa M, Hoshino H, Iwanaga K, Iwai H, Hamana Y, Ito M, Ohno K, Horio F

      Vol. 9 ( 5 ) page: e96271   2014.10

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  61. Detection of differentially expressed candidate genes for a fatty liver QTL on mouse chromosome 12 Reviewed

    Kobayashi M, Suzuki M, Ohno T, Tsuzuki K, Taguchi C, Tateishi S, Kawada T, Kim YI, Murai A, Horio F

    BMC Genet   Vol. 17 ( 1 ) page: 73   2016.1

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  62. Genetic dissection of the fatty Liver QTL Fl1sa by using congenic mice and identification of andidate genes in the liver and epididymal fat. Reviewed

    Suzuki M, Kobayashi M, Ohno T, Kanamori S, Tateishi S, Murai A, Horio F

    BMC Genet   Vol. 17 ( 1 ) page: 145   2016.2

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    Language:English   Publishing type:Research paper (scientific journal)  

  63. Bone Degeneration and Its Recovery in SMP30/GNL-Knockout Mice. Reviewed

    Nishijima K, Ohno T, Amano A, Kishimoto Y, Kondo Y, Ishigami A, Tanaka S

    J Nutr Health Aging   Vol. 21 ( 5 ) page: 573-578   2017.5

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    Language:English   Publishing type:Research paper (scientific journal)  

  64. Mesangial proliferative glomerulonephritis in murine malaria parasite, Plasmodium chabaudi AS, infected NC mice. Reviewed

    Yashima A, Mizuno M, Yuzawa Y, Shimada K, Suzuki N, Tawada H, Sato W, Tsuboi N, Maruyama S, Ito Y, Matsuo S, Ohno T

    Clin Exp Nephrol   Vol. 21 ( 4 ) page: 589-596   2017.4

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    Language:English   Publishing type:Research paper (scientific journal)  

  65. A new missense mutation in the paired domain of the mouse Pax3 gene. Reviewed

    Ohno T, Maegawa T, Katoh H, Miyasaka Y, Suzuki M, Kobayashi M, Horio F

    Exp Anim   Vol. 66 ( 3 ) page: 245-250   2017.7

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  66. Intestinal immunity suppresses carrying capacity of rats for the model tapeworm, Hymenolepis diminuta. Reviewed

    Ohno T, Kai T, Miyasaka Y, Maruyama H, Ishih A, Kino H

    Parasitol Int   Vol. 67 ( 4 ) page: 357-361   2018.4

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    Language:English   Publishing type:Research paper (scientific journal)  

  67. Congenic Mapping and Candidate Gene Analysis for Streptozotocin-Induced Diabetes Susceptibility Locus on Mouse Chromosome 11. Reviewed

    Maegawa T, Miyasaka Y, Kobayashi M, Babaya N, Ikegami H, Horio F, Takahash M, Ohno T

    Mamm Genome   Vol. 29 ( 3 ) page: 273-280   2018.4

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    Language:English   Publishing type:Research paper (scientific journal)  

  68. Age dependent changes of the mandible bone throughout the lifespan in female F344/N rat. Reviewed

    Nishijima K, Ohno T, Saito R, Sumi Y, Aoyama H, Tanaka S

    J Anat   Vol. 233 ( 4 ) page: 440-446   2018.8

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    Language:English   Publishing type:Research paper (scientific journal)  

  69. Mouse NC/Jic strain provides novel insights into host genetic factors for malaria research. Reviewed

    Ohno T, Miyasaka Y, Kuga M, Ushida K, Matsushima M, Kawabe T, Kikkawa Y, Mizuno M, Takahashi M

    Exp Anim   Vol. 68 ( 3 ) page: 243-255   2019.5

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    Authorship:Lead author   Language:English   Publishing type:Research paper (scientific journal)  

  70. SDR9C7 catalyzes critical dehydrogenation of acylceramides for skin barrier formation. Reviewed

    Takeichi T, Hirabayashi T, Miyasaka Y, Kawamoto A, Okuno Y, Taguchi S, Tanahashi K, Murase C, Takama H, Tanaka K, Boeglin WE, Calcutt MW, Watanabe D, Kono M, Muro Y, Ishikawa J, Ohno T, Brash AR, Akiyama M

    J Clin Invest   Vol. 130 ( 2 ) page: 890-903   2020.2

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    Language:English   Publishing type:Research paper (scientific journal)  

  71. Ablation of Iah1, a candidate gene for diet-induced fatty liver, does not affect liver lipid accumulation in mice. Reviewed

    Masuya T, Suzuki M, Tsujimura J, Kanamori S, Miyasaka Y, Ohno T, Murai A, Horio F, Kobayashi M

    Plos One   Vol. 15 ( 5 ) page: e0233087   2020.5

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    Language:English   Publishing type:Research paper (scientific journal)  

  72. Autoinflammatory keratinization disease with hepatitis and autism reveals roles for JAK1 kinase hyperactivity in autoinflammation. Reviewed

    Takeichi T, Lee JYW, Okuno Y, Miyasaka Y, Murase Y, Yoshikawa T, Tanahashi K, Nishida E, Okamoto T, Ito K, Muro Y, Sugiura K, Ohno T, McGrath JA, Akiyama M

    Front Immunol   Vol. 12   page: 737747   2022.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.3389/fimmu.2021.737747

  73. E3 ubiquitin ligase RNF123-deficient mice exhibite reduced parasitemia in mortality in rodent malaria (Plasmodium yoelii 17XL) infection. Reviewed

    Miyasaka Y, Niwa S, Masuya T, Ishii R, Kobayashi M, Horio F, Ohno T

    Parasitol Int   Vol. 88   page: 102542   2022.1

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.parint.2022.102542

  74. Effects of aging and delivery order on the breeding capacity of F344/N rats. Reviewed

    Sakamoto SH, Nishijima K, Ohno T, Tanaka S

    J Vet Med Sci   Vol. 84 ( 7 ) page: 960 - 963   2022.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1292/jvms.22-0111

  75. A novel ENU-induced Cpox mutation causes microcytic hypochromic anemia in mice. Reviewed

    Miyasaka Y, Okuda K, Miura I, Motegi H, Wakana S, Ohno T

    Exp Anim   Vol. 71 ( 4 ) page: 433 - 441   2022.10

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1538/expanim.22-0032

  76. A novel model mouse for type 2 diabetes mellitus with early onset and persistent hyperglycemia. Reviewed

    Ohno T, Miyasaka Y, Yoshida K, Kobayashi M, Horio F, Yokoi N, Mizuno M, Ikegami H

    Exp Anim   Vol. 71 ( 4 ) page: 510 - 518   2022.10

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    Authorship:Lead author, Last author   Language:English  

    DOI: 10.1538/expanim.22-0061

  77. Low ascorbic acid intake induces inflammatory changes in intestine and liver of ODS rats. Reviewed

    Kawade N, Suzuki W, Kobayashi M, Ohno T, Murai A, Horio F

    J Nutr Sci Vitaminol   Vol. 68 ( 6 ) page: 481 - 487   2022.12

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  78. Neonatal lethality of mouse A/J-7SM consomic strain is caused by an insertion mutation in the Dchs1 gene. Reviewed

    Miyasaka Y, Kobayashi T, Gotoh N, Kuga M, Kobayashi M, Horio F, Hashimoto K, Kawabe T, Ohno T

    Mamm Genome   Vol. 34 ( 1 ) page: 32 - 43   2023.3

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    Authorship:Last author, Corresponding author   Language:English   Publishing type:Research paper (scientific journal)  

  79. Effects of aging and reproductive history on bone parameters of common marmoset (Callithrix jacchus) mandibles. Reviewed

    Nishijima K, Saito R, Ohno T, Tanaka S

    Exp Anim   Vol. 72 ( 2 ) page: 193 - 198   2023.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1538/expanim.22-0110

  80. C3H/HeNSlc mouse with low phospholipid transfer protein expression showed dyslipidemia. Reviewed

    Kobayashi M, Kanbe F, Ishii R, Tsubouchi H, Hirai K, Miyasaka Y, Ohno T, Oda H, Ikeda S, Katoh H, Ichiyanagi K, Ishikawa A, Murai A, Horio F

    Sci Rep   Vol. 13 ( 1 ) page: 13813   2023.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1038/s41598-023-40917-9

  81. Splicing regulation of GFPT1 muscle-specific isoform and its roles in glucose metabolisms and neuromuscular junction. Reviewed International coauthorship

    Farshadyeganeh P, Nazim M, Zhang R, Ohkawara B, Nakajima K, Rahman MA, Nasrin F, Ito M, Takeda JI, Ohe K, Miyasaka Y, Ohno T, Masuda A, Ohno K

    iScience   Vol. 26 ( 10 ) page: 107746   2023.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.isci.2023.107746

  82. Calcitriol ameliorates motor deficits and prolongs survival of Chrne-deficient mouse, a model for congenital myasthenic syndrome, by inducing Rspo2. Reviewed

    Ohkawara B, Tomita H, Taro Inoue T, Zhang S, Kanbara S, Koshimizu H Miyasaka Y, Takeda J, Nishiwaki H, Nakashima H, Ito M, Masuda A, Ishiguro N, Ogi T, Ohno T, Imagama S, Ohno K

    Neurotherapeutics   Vol. 21 ( 2 ) page: e00318   2024.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.neurot.2024.e00318.

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Books 3

  1. スンクスの生物学(監修 磯村源蔵、編集 織田銑一、東家一雄、宮木孝昌)・スンクスにおける糖尿病モデルの開発

    大野民生( Role: Sole author)

    学会出版センター  2011.2 

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    Language:Japanese

  2. モデル動物の作製と維持(編 森脇和郎,米川博通,山村研一)・近交系化

    大野民生,西村正彦( Role: Joint author)

    エル・アイ・シー  2004 

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    Language:Japanese

  3. 分子の目で見た骨格筋の疲労(監修 吉岡利忠,編集 山田茂,後藤勝正)・収縮装置の老化

    瀬川岳志,大野民生,田中愼( Role: Joint author)

    ナップ  2003 

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    Language:Japanese

Presentations 4

  1. マウスを用いたネズミマラリア原虫感染に対する宿主抵抗性の遺伝的解析

    第49回日本実験動物学会シンポジウム「モデル動物による感染症研究の最前線」 

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    Event date: 2002.5

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  2. マウスを用いた寄生虫感染に対する宿主抵抗性/感受性遺伝子の解析

    第134回日本獣医学会ワークショップ「感染症研究と実験動物」 

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    Event date: 2002.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  3. マウスを用いたコスタリカ住血線虫感染感受性に関与する宿主遺伝子の解析

    第74回日本寄生虫学会ワークショップ「宿主・寄生虫関係;蠕虫」 

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    Event date: 2004.4

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

  4. マウスを用いたマラリア抵抗性遺伝子の解析

    大野民生

    第82回日本遺伝学会ワークショップ「マウス・ラットをモデルとした哺乳類遺伝学」 

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    Event date: 2010.9

    Language:Japanese   Presentation type:Oral presentation (invited, special)  

    Country:Japan  

Research Project for Joint Research, Competitive Funding, etc. 4

  1. NCマウスを用いた感染症とアレルギー疾患に共通する分子基盤の解析

    2006

    国内共同研究 

  2. マウスを用いたマラリア原虫感染に対する宿主抵抗性遺伝子の解析

    2005.4 - 2006.3

    日東学術振興財団研究助成 

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    Grant type:Competitive

  3. マウスを用いた寄生蠕虫感染に対する宿主抵抗性の遺伝的解析

    2002.4 - 2003.3

    日比野基金医学研究助成 

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    Grant type:Competitive

  4. 糖尿病自然発症スンクス(EDS系統)の病態解析

    2000.4 - 2001.3

    財団法人共済団医学研究奨励助成金 

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    Grant type:Competitive

KAKENHI (Grants-in-Aid for Scientific Research) 11

  1. NCマウスのアレルギー感受性に着目したアトピー性皮膚炎発症機構の遺伝学的解析

    Grant number:23K05600  2023.4 - 2026.3

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4680000 ( Direct Cost: \3600000 、 Indirect Cost:\108000 )

  2. 膜様条虫の寄生が糖尿病モデルマウスの高血糖を正常化する分子機構の基盤的解析

    Grant number:20K06460  2020.4 - 2023.3

    科学研究費補助金  基盤研究(C)

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    Authorship:Principal investigator 

  3. ODSラットを活用したビタミンCの抗炎症機能の実証と分子機構の解明

    Grant number:18H02155  2018.4 - 2021.3

    科学研究費補助金  基盤研究B

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    Authorship:Coinvestigator(s) 

    Grant amount:\1500000

  4. 新規赤血球因子を介したマラリア原虫増殖抑制機構の解明

    Grant number:17K07134  2017.4 - 2020.3

    科学研究費補助金  基盤研究(C)

    大野民生

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    Authorship:Principal investigator 

  5. マウス体系的遺伝解析系を用いたウレタン誘発肺腫瘍感受性の遺伝的解析

    2014.4 - 2017.3

    科学研究費補助金  基盤研究(C)

    大野民生

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    Authorship:Principal investigator 

  6. マウス体系的遺伝解析系を用いたストレプトゾトシン誘発糖尿病感受性遺伝子の解析

    2011.4 - 2014.3

    科学研究費補助金  基盤研究(C)

    大野民生

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    Authorship:Principal investigator 

  7. マウス・コンソミック系統群に見出された統合的致死現象の原因遺伝子の解析

    2007.4 - 2008.3

    科学研究費補助金  萌芽研究

    大野 民生

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    Authorship:Principal investigator 

  8. NCマウスを用いた感染症とアレルギー疾患に共通する分子基盤の解析

    2006.4 - 2010.3

    科学研究費補助金  基盤研究(B)

    大野民生

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    Authorship:Principal investigator 

  9. マウス・コンソミック系統群を用いた 糖・脂質代謝異常の原因遺伝子の解析

    2004.4 - 2005.3

    科学研究費補助金  若手研究(B)

    大野 民生

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    Authorship:Principal investigator 

  10. マウスを用いた脳マラリア発症に関与する宿生遺伝子の解析

    2001.4 - 2002.3

    科学研究費補助金  若手研究(B)

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    Authorship:Principal investigator 

  11. マウスにおけるマラリア原虫感染に対する宿主抵抗性遺伝子の染色体マッピング

    1998.4 - 1999.3

    科学研究費補助金  奨励研究

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    Authorship:Principal investigator 

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Teaching Experience (On-campus) 45

  1. 医動物検査学・講義実習

    2023

  2. 動物学・講義

    2023

  3. 生体と微生物(寄生虫学分野)・講義実習

    2023

  4. 生体と微生物(寄生虫学分野)・講義実習

    2022

  5. 動物学・講義

    2022

  6. 医動物検査学・講義実習

    2022

  7. 生体と微生物(寄生虫学分野)・講義実習

    2021

  8. 医動物検査学・講義実習

    2021

  9. 動物学・講義

    2021

  10. 生体と微生物(寄生虫学分野)・講義実習

    2020

  11. 医動物検査学・講義実習

    2020

  12. 動物学・講義

    2020

  13. 生体と微生物(寄生虫学分野)・講義実習

    2019

  14. 動物学・講義

    2019

  15. 医動物検査学・講義実習

    2019

  16. 生体と微生物(寄生虫学分野)・講義実習

    2018

  17. 医動物検査学・講義実習

    2018

  18. 実験動物学・講義

    2018

  19. 大学院基盤医科学実習(遺伝子改変マウスの遺伝的背景の統御)

    2018

  20. 生体と微生物(寄生虫学分野)・講義実習

    2017

  21. 医動物検査学・講義実習

    2017

  22. 実験動物学・講義

    2017

  23. 大学院基盤医科学実習(遺伝子改変マウスの遺伝的背景の統御)

    2017

  24. 自然環境と人間(分担)・講義

    2017

  25. 生体と微生物(寄生虫学分野)

    2016

  26. 医動物検査学

    2016

  27. 実験動物学

    2016

  28. 遺伝子改変マウスの遺伝的背景の統御

    2016

  29. 生体と微生物(寄生虫学分野)

    2015

  30. 実験動物学

    2015

  31. 遺伝子改変マウスの遺伝的背景の統御

    2015

  32. 実験動物学

    2014

  33. 生体と微生物(寄生虫学分野)

    2014

  34. 遺伝子改変マウスの遺伝的背景の統御

    2014

  35. 生体と微生物(寄生虫学分野)

    2013

  36. 遺伝子改変マウスの遺伝的背景の統御

    2013

  37. 自然環境と人間(分担)

    2013

  38. 実験動物学

    2013

  39. 生体と微生物(寄生虫学分野)

    2012

  40. 実験動物学

    2012

  41. 遺伝子改変マウスの遺伝的背景の統御

    2012

  42. 生体と微生物(寄生虫学分野)

    2011

  43. 実験動物学

    2011

  44. 遺伝子改変マウスの遺伝的背景の統御

    2011

  45. 実験動物学

    2010

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Teaching Experience (Off-campus) 17

  1. 医動物学

    2023.4 - 2024.3 Chubu University)

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    Level:Undergraduate (specialized)  Country:Japan

  2. 医動物学

    2022.4 - 2023.3 Chubu University)

  3. 医動物学

    2021.4 - 2022.3 Chubu University)

  4. 医動物学

    2020.4 - 2021.3 Chubu University)

  5. 医動物学

    2019.4 - 2020.3 Chubu University)

  6. 生体防御学(寄生虫学分野)

    2016.4 - 2017.3 Chubu University)

  7. 生体防御学(寄生虫学分野)

    2017.4 - 2018.3 Chubu University)

  8. 生体防御学(寄生虫学分野)

    2015.4 - 2016.3 Chubu University)

  9. 医動物学

    2013.4 - 2014.3 Chubu University)

  10. 医動物学

    2012.4 - 2013.3 Chubu University)

  11. 医動物学

    2011.4 - 2012.3 Chubu University)

  12. 医動物学

    2010.4 - 2011.3 Chubu University)

  13. 医動物学

    2009.4 - 2010.3 Chubu University)

  14. 実験動物学

    2008.4 - 2009.3 Chubu University)

  15. 実験動物学

    2007.4 - 2008.3 Chubu University)

  16. 実験動物学

    2006.4 - 2007.3 Chubu University)

  17. 医動物学

    2021.4 - 2021.9 Chubu University)

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    Level:Undergraduate (specialized) 

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Social Contribution 1

  1. 動物実験に関する外部検証専門員

    日本実験動物学会  2019.5