Updated on 2025/09/16
博士（医学） （ 2009.9 名古屋大学 ）
耳科学
Life Science / Otorhinolaryngology
The Oto-Rhino-Laryngological Society of Japan
日本耳科学会
日本聴覚医学会
Japan society of equilibrium research
The Society of Practical Otolaryngology
Yoshida, T; Ishino, T; Iwasaki, S; Oishi, N; Matsuda, Y; Tono, T; Sugahara, K; Yamazaki, H; Jitsukawa, S; Nakanishi, H; Kitoh, R; Sato, T; Kobayashi, M; Nishida, K; Nakaichi, T; Bruns, P; Bruns, P; Bruns, P; Bruns, P
PLOS ONE Vol. 20 ( 8 ) page： e0327124 2025.8
Cognitive function and speech outcomes after cochlear implantation in older adults Open Access
Yoshida, T; Kobayashi, M; Hara, D; Taniguchi, R; Fukunaga, Y; Sone, M
FRONTIERS IN NEUROLOGY Vol. 16 page： 1630946 2025.7
Direct Visualization of Tracer Permeation into the Endolymph in Human Patients Using MR Imaging Open Access
Naganawa, S; Ito, R; Kawamura, M; Taoka, T; Yoshida, T; Sone, M
MAGNETIC RESONANCE IN MEDICAL SCIENCES Vol. 24 ( 2 ) page： 253 - 261 2025
Factors influencing auditory brainstem response changes in infants Open Access
Esaki, T; Yoshida, T; Kobayashi, M; Morimoto, K; Shibata, C; Sone, M
INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY Vol. 185 page： 112094 2024.10
Correlation of Endolysmphatic Duct Signal Intensity With Clinical Features in Otological Diseases Open Access
Matsui, K; Yoshida, T; Sugimoto, S; Kobayashi, M; Naganawa, S; Sone, M
OTOLOGY & NEUROTOLOGY Vol. 45 ( 9 ) page： e624 - e629 2024.10
Efficacy of 100 hz sound stimulation on saccular dysfunction in meniere's disease Open Access
Sone, M; Ohgami, N; Katayama, N; Kobayashi, M; Gu, Y; Tong, K; Yoshida, T; Naganawa, S; Kato, M
ACTA OTO-LARYNGOLOGICA Vol. 144 ( 4 ) page： 272 - 276 2024.4
Clinical significance of posterior expansion of the utricular endolymphatic space Open Access
Kaida, H; Yoshida, T; Sugimoto, S; Kobayashi, M; Naganawa, S; Sone, M
ACTA OTO-LARYNGOLOGICA Vol. 144 ( 2 ) page： 107 - 111 2024.2
Naganawa, S; Ito, R; Kawamura, M; Taoka, T; Yoshida, T; Sone, M
MAGNETIC RESONANCE IN MEDICAL SCIENCES Vol. 23 ( 1 ) page： 80 - 91 2024
Disruption of the Blood-Perilymph Barrier Preceding Endolymphatic Hydrops Formation in Meniere's Disease Open Access
Kobayashi, M; Yoshida, T; Sugimoto, S; Naganawa, S; Sone, M
OTOLOGY & NEUROTOLOGY Vol. 44 ( 10 ) page： E766 - E767 2023.12
Yoshida, T; Hara, D; Kobayashi, M; Sugimoto, S; Fukunaga, Y; Sone, M
OTOLOGY & NEUROTOLOGY Vol. 44 ( 8 ) page： e560 - e565 2023.9
Association between Locomotive Syndrome and Hearing Loss in Community-Dwelling Adults Open Access
Ito, S; Nakashima, H; Segi, N; Ouchida, J; Ishizuka, S; Takegami, Y; Yoshida, T; Hasegawa, Y; Imagama, S
JOURNAL OF CLINICAL MEDICINE Vol. 12 ( 17 ) 2023.9
Fluid signal suppression characteristics of 3D-FLAIR with a T2 selective inversion pulse in the skull base Open Access
Naganawa, S; Kato, Y; Yoshida, T; Sone, M
NATURE COMMUNICATIONS Vol. 14 ( 1 ) page： 4915 2023.8
Comparative Analysis of Cartilage Conduction Hearing Aid Users and Non-Users: An Investigative Study Open Access
Sugimoto, S; Yoshida, T; Fukunaga, Y; Motegi, A; Saito, K; Kobayashi, M; Sone, M
AUDIOLOGY RESEARCH Vol. 13 ( 4 ) page： 563 - 572 2023.8
Labyrinthine calcification in ears with otitis media and antineutrophil cytoplasmic antibody-associated vasculitis (OMAAV): A report of two cases
Yoshida Tadao, Kobayashi Masumi, Sugimoto Satofumi, Naganawa Shinji, Sone Michihiko
AURIS NASUS LARYNX Vol. 50 ( 2 ) page： 299 - 304 2023.4
Impact of endolymphatic hydrops on DPOAE in subjects with normal to mild hearing loss
Inagaki Kei, Yoshida Tadao, Kobayashi Masumi, Sugimoto Satofumi, Fukunaga Yukari, Hara Daisuke, Naganawa Shinji, Sone Michihiko
LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY Vol. 8 ( 1 ) page： 262 - 268 2023.2
Yoshida, T; Naganawa, S; Kobayashi, M; Sugimoto, S; Katayama, N; Nakashima, T; Kato, Y; Ichikawa, K; Yamaguchi, H; Nishida, K; Sone, M
FRONTIERS IN NEUROLOGY Vol. 13 page： 1016577 2022.11
Iwasa, Y; Nishio, S; Yoshimura, H; Sugaya, A; Kataoka, Y; Maeda, Y; Kanda, Y; Nagai, K; Naito, Y; Yamazaki, H; Ikezono, T; Matsuda, H; Nakai, M; Tona, R; Sakurai, Y; Motegi, R; Takeda, H; Kobayashi, M; Kihara, C; Ishino, T; Morita, S; Iwasaki, S; Takahashi, M; Furutate, S; Oka, S; Kubota, T; Arai, Y; Kobayashi, Y; Kikuchi, D; Shintani, T; Ogasawara, N; Honkura, Y; Izumi, S; Hyogo, M; Ninoyu, Y; Suematsu, M; Nakayama, J; Tsuchihashi, N; Okami, M; Sakata, H; Yoshihashi, H; Kobayashi, T; Kumakawa, K; Yoshida, T; Esaki, T; Usami, S
HUMAN GENETICS Vol. 141 ( 3-4 ) page： 865 - 875 2022.4
Naganawa, S; Ito, R; Kawai, H; Kawamura, M; Taoka, T; Yoshida, T; Sone, M
MAGNETIC RESONANCE IN MEDICAL SCIENCES Vol. 21 ( 3 ) page： 459 - 467 2022
Facial nerve palsy associated with chronic recurrent multifocal osteomyelitis
Yang, CJ; Yoshida, T; Sugimoto, S; Teranishi, M; Sone, M
PEDIATRICS INTERNATIONAL Vol. 63 ( 9 ) page： 1125 - 1127 2021.9
Nakashima, T; Katayama, N; Saji, N; Teranishi, M; Yoshida, T; Suzuki, H; Sone, M; Hamajima, N
NUTRITION Vol. 89 page： 111268 2021.9
Evaluation of the blood-perilymph barrier in ears with endolymphatic hydrops Open Access
Yoshida, T; Kobayashi, M; Sugimoto, S; Teranishi, M; Naganawa, S; Sone, M
ACTA OTO-LARYNGOLOGICA Vol. 141 ( 8 ) page： 736 - 741 2021.8
Morioka, M; Sugimoto, S; Yoshida, T; Teranishi, M; Kobayashi, M; Nishio, N; Katayama, N; Naganawa, S; Sone, M
OTOLOGY & NEUROTOLOGY Vol. 42 ( 6 ) page： E643 - E647 2021.7
Cochlear implantation in patient with Charcot-Marie-Tooth disease Open Access
Kobayashi, M; Yoshida, T; Sugimoto, S; Teranishi, M; Hara, D; Kimata, Y; Sone, M
AURIS NASUS LARYNX Vol. 48 ( 2 ) page： 327 - 330 2021.4
Harabuchi, Y; Kishibe, K; Tateyama, K; Morita, Y; Yoshida, N; Okada, M; Kunimoto, Y; Watanabe, T; Inagaki, A; Yoshida, T; Imaizumi, M; Nakamura, T; Matsunobu, T; Kobayashi, S; Iino, Y; Murakami, S; Takahashi, H; Tono, T
AURIS NASUS LARYNX Vol. 48 ( 1 ) page： 2 - 14 2021.2
Effects of endolymphatic hydrops on acoustic energy absorbance
Kobayashi, M; Yoshida, T; Sugimoto, S; Shimono, M; Teranishi, M; Naganawa, S; Sone, M
ACTA OTO-LARYNGOLOGICA Vol. 140 ( 8 ) page： 626 - 631 2020.7
Naganawa, S; Ito, R; Kawai, H; Taoka, T; Yoshida, T; Sone, M
MAGNETIC RESONANCE IN MEDICAL SCIENCES Vol. 19 ( 4 ) page： 375 - 381 2020
Clinical Features of Ears With Otosclerosis and Endolymphatic Hydrops Open Access
Wang, F; Yoshida, T; Sugimoto, S; Shimono, M; Teranishi, M; Naganawa, S; Sone, M
OTOLOGY & NEUROTOLOGY Vol. 40 ( 4 ) page： 441 - 445 2019.4
Association between Uncoupling Protein 2 Gene Ala55val Polymorphism and Sudden Sensorineural Hearing Loss. Open Access
Koide Y, Teranishi M, Sugiura S, Uchida Y, Nishio N, Kato K, Otake H, Yoshida T, Otsuka R, Ando F, Shimokata H, Hasegawa Y, Nakashima T, Sone M
The journal of international advanced otology Vol. 14 ( 2 ) page： 166 - 169 2018.8
Imaging of the endolymphatic space in patients with Meniere's disease
Yoshida Tadao, Sugimoto Satofumi, Teranishi Masaaki, Otake Hironao, Yamazaki Masahiro, Naganawa Shinji, Nakashima Tsutomu, Sone Michihiko
AURIS NASUS LARYNX Vol. 45 ( 1 ) page： 33 - 38 2018.2
Idiopathic sudden sensorineural hearing loss and acute low-tone sensorineural hearing loss: a comparison of the results of a nationwide epidemiological survey in Japan
Yoshida Tadao, Sone Michihiko, Kitoh Ryosuke, Nishio Shin-ya, Ogawa Kaoru, Kanzaki Sho, Hato Naohito, Fukuda Satoshi, Hara Akira, Ikezono Tetsuo, Ishikawa Kotaro, Iwasaki Satoshi, Kaga Kimitaka, Kakehata Seiji, Matsubara Atsushi, Matsunaga Tatsuo, Murata Takaaki, Naito Yasushi, Nakagawa Takashi, Nishizaki Kazunori, Noguchi Yoshihiro, Sano Hajime, Sato Hiroaki, Suzuki Mikio, Shojaku Hideo, Takahashi Haruo, Takeda Hidehiko, Tono Testuya, Yamashita Hiroshi, Yamasoba Tatsuya, Usami Shin-ichi
ACTA OTO-LARYNGOLOGICA Vol. 137 ( sup565 ) page： S38 - S43 2017
The relationship between endolymphatic hydrops in the vestibule and low-frequency air-bone gaps. Reviewed
Sugimoto S, Yoshida T, Teranishi M, Okazaki Y, Naganawa S, Sone M
The Laryngoscope 2017.11
Accuracy of 3.0 Tesla magnetic resonance imaging in the diagnosis of intracochlear schwannoma. Reviewed
Yoshida, T. Sone, M. Naganawa, S. Nakashima, T.
Auris Nasus Larynx page： 551-4 2011.8
Intratympanic membrane congenital cholesteatoma.
Yoshida T, Sone M, Mizuno T, Nakashima T.
Int J Pediatr Otorhinolaryngol. page： 1003-5 2009.7
Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging findings and prognosis in sudden sensorineural hearing loss.
Yoshida T, Sugiura M, Naganawa S, Teranishi M, Nakata S, Nakashima T.
Laryngoscope page： 1433-7 2008.8
人工内耳両側装用者における聴覚処理プロセスの解明
Grant number：20K11183 2020.4 - 2023.3
吉田 忠雄
Authorship：Principal investigator
Grant amount：\4160000 （ Direct Cost: \3200000 、 Indirect Cost：\960000 ）
成人の人工内耳両側装用は2017年に人工内耳適応基準が改定になったことを受け増加傾向にあるが、その実際の効果についてはまだ明らかとなっていない。人工内耳機器にも現状では健聴者の聴覚能と比較して限界があるのも事実である。
本研究では、高度から重度の感音難聴患者が人工内耳を両側に装用することによって生じる潜在的効果および表情認識によって読話能力が評価可能であるかどうかについて検討を行う。両側装用のさらなる利点、欠点を明らかにすることで人工内耳の機器選択、プログラムの開発、リハビリテーションの技術向上に貢献すると考えられる。
Examination of deafness onset mechanism using MYH9 abnormality model mouse
Grant number：16K20240 2016.4 - 2020.3
YOSHIDA TADAO
Authorship：Principal investigator
Grant amount：\3770000 （ Direct Cost: \2900000 、 Indirect Cost：\870000 ）
The results of ABR in R702C-Atoth1 mice revealed that some mice caused hearing loss and others did not. Three out of 46 mice showed 70 dB or more in all frequency ranges. Immunostaining was performed using NMMHC-IIA (MYH9). A negative control was prepared. The expression site of the NMMHC-IIA in the inner ear was compared in three individuals in one wild-type gene expression and two expressing the deafness in the R702C-Atoth1 mice. As shown in FIGS. 2 and 3, the expression was almost the same as that of the wild type, and there was no difference between individuals. No morphological changes were observed on light microscopy and immunostaining. Since only a very small amount of the inner ear tissue sample can be obtained, the amount was insufficient to confirm that the MYH R702C gene was contained in the inner ear in a tissue-specific manner. In the future, we will focus on the morphological change of sensory hair, which is a finer structure, and study it repeatedly.
