Updated on 2023/04/14
博士（医学） （ 2009.9 名古屋大学 ）
耳科学
Life Science / Otorhinolaryngology
The Oto-Rhino-Laryngological Society of Japan
日本耳科学会
日本聴覚医学会
Japan society of equilibrium research
The Society of Practical Otolaryngology
Labyrinthine calcification in ears with otitis media and antineutrophil cytoplasmic antibody-associated vasculitis (OMAAV): A report of two cases
Yoshida Tadao, Kobayashi Masumi, Sugimoto Satofumi, Naganawa Shinji, Sone Michihiko
AURIS NASUS LARYNX Vol. 50 ( 2 ) page： 299 - 304 2023.4
Impact of endolymphatic hydrops on DPOAE in subjects with normal to mild hearing loss
Inagaki Kei, Yoshida Tadao, Kobayashi Masumi, Sugimoto Satofumi, Fukunaga Yukari, Hara Daisuke, Naganawa Shinji, Sone Michihiko
LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY Vol. 8 ( 1 ) page： 262 - 268 2023.2
Evaluation of the blood-perilymph barrier in ears with endolymphatic hydrops
Yoshida Tadao, Kobayashi Masumi, Sugimoto Satofumi, Teranishi Masaaki, Naganawa Shinji, Sone Michihiko
ACTA OTO-LARYNGOLOGICA Vol. 141 ( 8 ) page： 736 - 741 2021.8
Cochlear implantation in patient with Charcot-Marie-Tooth disease
Kobayashi Masumi, Yoshida Tadao, Sugimoto Satofumi, Teranishi Masaaki, Hara Daisuke, Kimata Yukari, Sone Michihiko
AURIS NASUS LARYNX Vol. 48 ( 2 ) page： 327 - 330 2021.4
Confirmation of Age-dependence in the Leakage of Contrast Medium around the Cortical Veins into Cerebrospinal Fluid after Intravenous Administration of Gadolinium-based Contrast Agent
Naganawa Shinji, Ito Rintaro, Kawai Hisashi, Taoka Toshiaki, Yoshida Tadao, Sone Michihiko
MAGNETIC RESONANCE IN MEDICAL SCIENCES Vol. 19 ( 4 ) page： 375 - 381 2020
Clinical Features of Ears With Otosclerosis and Endolymphatic Hydrops
Wang Fei, Yoshida Tadao, Sugimoto Satofumi, Shimono Mariko, Teranishi Masaaki, Naganawa Shinji, Sone Michihiko
OTOLOGY & NEUROTOLOGY Vol. 40 ( 4 ) page： 441 - 445 2019.4
Association between Uncoupling Protein 2 Gene Ala55val Polymorphism and Sudden Sensorineural Hearing Loss.
Koide Y, Teranishi M, Sugiura S, Uchida Y, Nishio N, Kato K, Otake H, Yoshida T, Otsuka R, Ando F, Shimokata H, Hasegawa Y, Nakashima T, Sone M
The journal of international advanced otology Vol. 14 ( 2 ) page： 166 - 169 2018.8
Imaging of the endolymphatic space in patients with Meniere's disease
Yoshida Tadao, Sugimoto Satofumi, Teranishi Masaaki, Otake Hironao, Yamazaki Masahiro, Naganawa Shinji, Nakashima Tsutomu, Sone Michihiko
AURIS NASUS LARYNX Vol. 45 ( 1 ) page： 33 - 38 2018.2
Idiopathic sudden sensorineural hearing loss and acute low-tone sensorineural hearing loss: a comparison of the results of a nationwide epidemiological survey in Japan
Yoshida Tadao, Sone Michihiko, Kitoh Ryosuke, Nishio Shin-ya, Ogawa Kaoru, Kanzaki Sho, Hato Naohito, Fukuda Satoshi, Hara Akira, Ikezono Tetsuo, Ishikawa Kotaro, Iwasaki Satoshi, Kaga Kimitaka, Kakehata Seiji, Matsubara Atsushi, Matsunaga Tatsuo, Murata Takaaki, Naito Yasushi, Nakagawa Takashi, Nishizaki Kazunori, Noguchi Yoshihiro, Sano Hajime, Sato Hiroaki, Suzuki Mikio, Shojaku Hideo, Takahashi Haruo, Takeda Hidehiko, Tono Testuya, Yamashita Hiroshi, Yamasoba Tatsuya, Usami Shin-ichi
ACTA OTO-LARYNGOLOGICA Vol. 137 ( sup565 ) page： S38 - S43 2017
The relationship between endolymphatic hydrops in the vestibule and low-frequency air-bone gaps. Reviewed
Sugimoto S, Yoshida T, Teranishi M, Okazaki Y, Naganawa S, Sone M
The Laryngoscope 2017.11
Accuracy of 3.0 Tesla magnetic resonance imaging in the diagnosis of intracochlear schwannoma. Reviewed
Yoshida, T. Sone, M. Naganawa, S. Nakashima, T.
Auris Nasus Larynx page： 551-4 2011.8
Intratympanic membrane congenital cholesteatoma.
Yoshida T, Sone M, Mizuno T, Nakashima T.
Int J Pediatr Otorhinolaryngol. page： 1003-5 2009.7
Three-dimensional fluid-attenuated inversion recovery magnetic resonance imaging findings and prognosis in sudden sensorineural hearing loss.
Yoshida T, Sugiura M, Naganawa S, Teranishi M, Nakata S, Nakashima T.
Laryngoscope page： 1433-7 2008.8
人工内耳両側装用者における聴覚処理プロセスの解明
Grant number：20K11183 2020.4 - 2023.3
吉田 忠雄
Authorship：Principal investigator
Grant amount：\4160000 （ Direct Cost: \3200000 、 Indirect Cost：\960000 ）
成人の人工内耳両側装用は2017年に人工内耳適応基準が改定になったことを受け増加傾向にあるが、その実際の効果についてはまだ明らかとなっていない。人工内耳機器にも現状では健聴者の聴覚能と比較して限界があるのも事実である。
本研究では、高度から重度の感音難聴患者が人工内耳を両側に装用することによって生じる潜在的効果および表情認識によって読話能力が評価可能であるかどうかについて検討を行う。両側装用のさらなる利点、欠点を明らかにすることで人工内耳の機器選択、プログラムの開発、リハビリテーションの技術向上に貢献すると考えられる。
Examination of deafness onset mechanism using MYH9 abnormality model mouse
Grant number：16K20240 2016.4 - 2020.3
YOSHIDA TADAO
Authorship：Principal investigator
Grant amount：\3770000 （ Direct Cost: \2900000 、 Indirect Cost：\870000 ）
The results of ABR in R702C-Atoth1 mice revealed that some mice caused hearing loss and others did not. Three out of 46 mice showed 70 dB or more in all frequency ranges. Immunostaining was performed using NMMHC-IIA (MYH9). A negative control was prepared. The expression site of the NMMHC-IIA in the inner ear was compared in three individuals in one wild-type gene expression and two expressing the deafness in the R702C-Atoth1 mice. As shown in FIGS. 2 and 3, the expression was almost the same as that of the wild type, and there was no difference between individuals. No morphological changes were observed on light microscopy and immunostaining. Since only a very small amount of the inner ear tissue sample can be obtained, the amount was insufficient to confirm that the MYH R702C gene was contained in the inner ear in a tissue-specific manner. In the future, we will focus on the morphological change of sensory hair, which is a finer structure, and study it repeatedly.
