Faculty Profiles - OKAJIMA, Tetsuya

Papers - OKAJIMA, Tetsuya

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Roles of asialo-series ganglioside GD1α in human cancer cell lines. Reviewed

Bhuiyan, RH; Yesmin, F; Kondo, Y; Ohkawa, Y; Ohmi, Y; Zhang, P; Okajima, T; Furukawa, K; Furukawa, K

CANCER SCIENCE Vol. 112 page： 679 - 679 2021.2

Ganglioside GD2 enhances malignant properties of melanoma by co-operating with integrin. Reviewed

Yesmin, F; Bhuiyan, RH; Ohmi, Y; Okajima, T; Yamamoto, S; Furukawa, K; Furukawa, K

CANCER SCIENCE Vol. 112 page： 699 - 699 2021.2

Enzyme assay of O-fucosyltransferase 1 using Drosophila OFUT1.

Nishihara S, Angata K, Aoki-Kinoshita KF, Hirabayashi J, Okajima T

2021

Enzyme assay of O-GlcNAc transferase.

Nishihara S, Angata K, Aoki-Kinoshita KF, Hirabayashi J, Alam SMD, Okajima T

2021

3′-Sialyllactose on Notch: NOTCH1 functions as a scafold of O-linked, 3′-sialyllactosylated glycans

Tsukamoto, Y; Aoki, K; Narimatsu, Y; Urata, Y; Saiki, W; Ogawa, M; Clausen, H; Tiemeyer, M; Okajima, T; Takeuchi, H

GLYCOBIOLOGY Vol. 30 ( 12 ) page： 1119 - 1120 2020.12

N-glycans on EGF domain-specific O-GlcNAc transferase (EOGT) facilitate EOGT maturation and peripheral endoplasmic reticulum localization

Alam, SMD; Tsukamoto, Y; Ogawa, M; Senoo, Y; Ikeda, K; Tashima, Y; Takeuchi, H; Okajima, T

GLYCOBIOLOGY Vol. 30 ( 12 ) page： 1031 - 1032 2020.12

Comprehensive O-GlcNAc glycoproteomics on NOTCH1 EGF repeats refined the sequons for O-GlcNAcylation and uncovered unique Lewis X epitopes in mammals

Ogawa, M; Tsukamoto, Y; Yogi, K; Senoo, Y; Ikeda, K; Takeuchi, H; Okajima, T

GLYCOBIOLOGY Vol. 30 ( 12 ) page： 1086 - 1087 2020.12

Glycoproteomic analysis identifies cryptdin-related sequence 1 as <i>O</i>-glycosylated protein modified with α1,2-fucose in the small intestine Reviewed

Hashiguchi, H; Tsukamoto, Y; Ogawa, M; Tashima, Y; Takeuchi, H; Nakamura, M; Kawashima, H; Fujishiro, M; Okajima, T

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS Vol. 695 page： 108653 2020.11

Differential Labeling of Glycoproteins with Alkynyl Fucose Analogs Reviewed

Ma Chenyu, Takeuchi Hideyuki, Hao Huilin, Yonekawa Chizuko, Nakajima Kazuki, Nagae Masamichi, Okajima Tetsuya, Haltiwanger Robert S., Kizuka Yasuhiko

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol. 21 ( 17 ) 2020.9

Aminoglycosides are efficient reagents to induce readthrough of premature termination codon in mutant B4GALNT1 genes found in families of hereditary spastic paraplegia.

Yesmin F, Bhuiyan RH, Ohmi Y, Ohkawa Y, Tajima O, Okajima T, Furukawa K, Furukawa K

Journal of biochemistry Vol. 168 ( 2 ) page： 103 - 112 2020.8

N-Glycans on EGF domain-specificO-GlcNAc transferase (EOGT) facilitate EOGT maturation and peripheral endoplasmic reticulum localization

Alam Sayad Md. Didarul, Tsukamoto Yohei, Ogawa Mitsutaka, Senoo Yuya, Ikeda Kazutaka, Tashima Yuko, Takeuchi Hideyuki, Okajima Tetsuya

JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 295 ( 25 ) page： 8560 - 8574 2020.6

Contribution of extracellular O-GlcNAc to the stability of folded epidermal growth factor-like domains and Notch1 trafficking

Ogawa Mitsutaka, Tashima Yuko, Sakaguchi Yamato, Takeuchi Hideyuki, Okajima Tetsuya

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS Vol. 526 ( 1 ) page： 184 - 190 2020.5

Xylosyl Extension of O-Glucose Glycans on the Extracellular Domain of NOTCH1 and NOTCH2 Regulates Notch Cell Surface Trafficking

Urata Yusuke, Saiki Wataru, Tsukamoto Yohei, Sago Hiroaki, Hibi Hideharu, Okajima Tetsuya, Takeuchi Hideyuki

CELLS Vol. 9 ( 5 ) 2020.5

The ceramide moiety of disialoganglioside (GD3) is essential for GD3 recognition by the sialic acid-binding lectin SIGLEC7 on the cell surface

Hashimoto Noboru, Ito Shizuka, Tsuchida Akiko, Bhuiyan Robiul H., Okajima Tetsuya, Yamamoto Akihito, Furukawa Keiko, Ohmi Yuhsuke, Furukawa Koichi

JOURNAL OF BIOLOGICAL CHEMISTRY Vol. 294 ( 28 ) page： 10833 - 10845 2019.7

Extracellular O-GlcNAc: From Discovery to Current Developments

Okajima Tetsuya

TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY Vol. 31 ( 181 ) page： SE57 - SE58 2019.7

Structure and function of extracellular <i>O</i>-GlcNAc

Ogawa, M; Okajima, T

CURRENT OPINION IN STRUCTURAL BIOLOGY Vol. 56 page： 72 - 77 2019.6

Loss of Enzyme Activity in Mutated B4GALNT1 Gene Products in Patients with Hereditary Spastic Paraplegia Results in Relatively Mild Neurological Disorders: Similarity with Phenotypes of B4galnt1 Knockout Mice

Bhuiyan Robiul H., Ohmi Yuhsuke, Ohkawa Yuki, Zhang Pu, Takano Maiko, Hashimoto Noboru, Okajima Tetsuya, Furukawa Keiko, Furukawa Koichi

NEUROSCIENCE Vol. 397 page： 94 - 106 2019.1

Structure and function of extracellular O-GlcNAc Invited Reviewed

Mitsutaka Ogawa, Tetsuya Okajima

Current Opinion in Structural Biology Vol. 56 page： 72-77 2019

Significant roles of O-glucose glycans in mammalian Notch trafficking and signaling

Takeuchi, H; Yu, HJ; Hao, HL; Urata, Y; Senoo, Y; Tsukamoto, Y; Saiki, W; Takeuchi, M; Ito, A; Li, HL; Okajima, T; Haltiwanger, RS

GLYCOBIOLOGY Vol. 28 ( 12 ) page： 1017 - 1018 2018.12

Exploring the significance of xylosyl-extension of O-glucose glycans on EGF repeats for Notch signaling in mammals

Saiki, W; Urata, Y; Senoo, Y; Tsukamoto, Y; Ma, CY; Okajima, T; Takeuchi, H

GLYCOBIOLOGY Vol. 28 ( 12 ) page： 1028 - 1029 2018.12

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Papers - OKAJIMA, Tetsuya