Faculty Profiles - OKAJIMA, Tetsuya

Papers - OKAJIMA, Tetsuya

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Characterization of galactosyltransferase and sialyltransferase genes mediating the elongation of the extracellular O-GlcNAc glycans.

Tsukamoto Y, Tsukamoto N, Saiki W, Tashima Y, Furukawa JI, Kizuka Y, Narimatsu Y, Clausen H, Takeuchi H, Okajima T

Biochemical and biophysical research communications Vol. 703 page： 149610 2024.4

Efficient Escorting Strategy for Aggregation-Prone Notch EGF Repeats with Sparcl1

Kondo, Y; Li, YX; Okajima, T

MOLECULES Vol. 29 ( 5 ) 2024.3

3'-Sialyllactose on Notch: Notch1 functions as a scaffold of O-linked, 3'-sialyllactosylated glycans

Tsukamoto, Y; Aoki, K; Narimatsu, Y; Urata, Y; Saiki, W; Tiemeyer, M; Clausen, H; Kurebayashi, Y; Minami, A; Takahashi, T; Okajima, T; Takeuchi, H

GLYCOBIOLOGY Vol. 33 ( 11 ) page： 977 - 977 2023.12

Quality control of NOTCH and CRB2 proteins containing epidermal growth factor-like EGF repeats by xylosyl elongation of O-glucose glycans

Takeuchi, H; Mita, Y; Tsukamoto, Y; Saiki, W; Kato, K; Urata, Y; Kurebayashi, Y; Minami, A; Takahashi, T; Hibi, H; Okajima, T

GLYCOBIOLOGY Vol. 33 ( 11 ) page： 997 - 998 2023.12

Inhibitory machinery for the functional dystroglycan glycosylation

Kondo, Y; Okajima, T

JOURNAL OF BIOCHEMISTRY Vol. 173 ( 5 ) page： 333 - 335 2023.5

Evidence that only EWS among the FET proteins acquires a low partitioning property for the hyperosmotic stress response by O-GlcNAc glycosylation on its low-complexity domain

Kakuo, M; Horii, T; Tonomura, N; Sato, R; Ogawa, M; Okajima, T; Kamemura, K

EXPERIMENTAL CELL RESEARCH Vol. 424 ( 1 ) page： 113504 2023.3

Secretory expression of mammalian NOTCH tandem epidermal growth factor-like repeats based on increased O-glycosylation

Zhang, AL; Tsukamoto, Y; Takeuchi, H; Nishiwaki, K; Tashima, Y; Okajima, T

ANALYTICAL BIOCHEMISTRY Vol. 656 page： 114881 2022.11

Roles of POFUT1 and POGLUT1 for the effective transport of DLK1 to the cell surface

Tashima, Y; Goto, W; Tsukamoto, Y; Ogawa, M; Takeuchi, H; Okajima, T

GLYCOBIOLOGY Vol. 32 ( 11 ) page： 1002 - 1003 2022.10

3′-Sialyllactose on Notch: Notch1 functions as a scaffold of O-linked, 3′-sialyllactosylated glycans

Tsukamoto, Y; Aoki, K; Narimatsu, Y; Urata, Y; Saiki, W; Tiemeyer, M; Clausen, H; Kurebayashi, Y; Minami, A; Takahashi, T; Okajima, T; Takeuchi, H

GLYCOBIOLOGY Vol. 32 ( 11 ) page： 1022 - 1022 2022.10

Glycoproteomics of NOTCH1 EGF repeat fragments overexpressed with different glycosyltransferases in HEK293T cells reveals insights into O-GlcNAcylation of NOTCH1

Tsukamoto, Y; Ogawa, M; Yogi, K; Tashima, Y; Takeuchi, H; Okajima, T

GLYCOBIOLOGY Vol. 32 ( 7 ) page： 616 - 628 2022.6

Significant Roles of Notch O-Glycosylation in Cancer

Wang, WW; Okajima, T; Takeuchi, H

MOLECULES Vol. 27 ( 6 ) 2022.3

Ganglioside GD2 enhances malignant properties of melanoma by co-operating with integrin.

Farhana, Y; Bhuiyan, RH; Ohmi, Y; Horiuchi, M; Okajima, T; Yamamoto, S; Furukawa, K; Furukawa, K

CANCER SCIENCE Vol. 113 page： 1104 - 1104 2022.2

Unique effects of expression of asialo-series ganglioside GD1alpha in human cancer cell lines

Robiul, B; Yesmin, F; Kondo, Y; Ohkawa, Y; Ohmi, Y; Zhang, P; Okajima, T; Furukawa, K; Furukawa, K

CANCER SCIENCE Vol. 113 page： 379 - 379 2022.2

Eogt-catalyzed O-GlcNAcylation

Lo, PW; Okajima, T

TRENDS IN GLYCOSCIENCE AND GLYCOTECHNOLOGY Vol. 34 ( 197 ) page： E1 - E6 2022.1

Ganglioside GD2 Enhances the Malignant Phenotypes of Melanoma Cells by Cooperating with Integrins

Yesmin, F; Bhuiyan, RH; Ohmi, Y; Yamamoto, S; Kaneko, K; Ohkawa, Y; Zhang, P; Hamamura, K; Cheung, NKV; Kotani, N; Honke, K; Okajima, T; Kambe, M; Tajima, O; Furukawa, K; Furukawa, K

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES Vol. 23 ( 1 ) 2022.1

Other Classes of Eukaryotic Glycans

Haltiwanger RS, Wells L, Freeze HH, Jafar-Nejad H, Okajima T, Stanley P, Varki A, Cummings RD, Esko JD, Stanley P, Hart GW, Aebi M, Mohnen D, Kinoshita T, Packer NH, Prestegard JH, Schnaar RL, Seeberger PH

2022

St8sia1-deficiency in mice alters tumor environments of gliomas, leading to reduced disease severity Reviewed

Thane, P; Ohkawa, Y; Yamamoto, S; Momota, H; Kato, A; Kaneko, K; Natsume, A; Farhana, Y; Ohmi, Y; Okajima, T; Bhuiyan, RH; Wakabayashi, T; Furukawa, K; Furukawa, K

NAGOYA JOURNAL OF MEDICAL SCIENCE Vol. 83 ( 3 ) page： 535 - 549 2021.8

Majority of alpha2,6-sialylated glycans in the adult mouse brain exist in O-glycans: SALSA-MS analysis for knockout mice of alpha2,6-sialyltransferase genes Reviewed

Ohmi, Y; Nishikaze, T; Kitaura, Y; Ito, T; Yamamoto, S; Sugiyama, F; Matsuyama, M; Takahashi, Y; Takeda, A; Kawahara, T; Okajima, T; Furukawa, K; Furukawa, K

GLYCOBIOLOGY Vol. 31 ( 5 ) page： 557 - 570 2021.5

Bioinformatics and Functional Analyses Implicate Potential Roles for EOGT and L-fringe in Pancreatic Cancers Reviewed

Barua, R; Mizuno, K; Tashima, Y; Ogawa, M; Takeuchi, H; Taguchi, A; Okajima, T

MOLECULES Vol. 26 ( 4 ) 2021.2

Current Views on the Roles of O-Glycosylation in Controlling Notch-Ligand Interactions Reviewed

Saiki, W; Ma, CY; Okajima, T; Takeuchi, H

BIOMOLECULES Vol. 11 ( 2 ) 2021.2

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Papers - OKAJIMA, Tetsuya