Award type：Award from publisher, newspaper, foundation, etc.  Country：Japan

Country：Japan

Award type：Award from Japanese society, conference, symposium, etc.  Country：Japan

Award type：Award from Japanese society, conference, symposium, etc.  Country：Japan

Country：Japan

Country：Japan

Award type：Award from publisher, newspaper, foundation, etc.  Country：Japan

Award type：Award from Japanese society, conference, symposium, etc.  Country：Japan

Award type：Award from publisher, newspaper, foundation, etc.  Country：Japan

Award type：Award from Japanese society, conference, symposium, etc.  Country：Japan

Award type：Award from Japanese society, conference, symposium, etc.  Country：Japan

Award type：Award from international society, conference, symposium, etc.  Country：Germany

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1039/D1CC05171G

DOI： 10.1039/D1CC05171G

Authorship：Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

A practical and environmentally benign method for the oxidative Ritter-type chloroamidation of alkenes was developed using sodium chloride and oxone as a chlorinating source and an oxidant, respectively. The reaction proceeded smoothly under non-aqueous conditions without the use of any catalyst. Excellent chemoselectivity (i. e., chloroamidation versus dichlorination) could be achieved for electron-deficient styrenes. In addition, this protocol could be easily applied to 7-gram-scale synthesis.

DOI： 10.1002/ajoc.202100575

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.15227/orgsyn.098.0028

Web of Science

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.15227/orgsyn.098.0001

Web of Science

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

A chemoselective I+/TBHP catalysis was developed for tandem oxidative cyclization/aromatization of indole derivatives under nearly neutral conditions to give the corresponding indolo[2,3-b]quinoline sulfonate salts, which could be easily isolated via only simple filtration of the crude reaction mixture. Interestingly both ionic and radical active species would be generated in situ for the corresponding oxidative transformations to proceed in a chemoselective manner.

DOI： 10.1002/ajoc.202000570

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

We developed the hypoiodite-catalyzed tandem dearomative peroxycyclization of homotryptamine derivatives to peroxytetrahydropyridoindolenines under mild conditions. During the course of a mechanistic study, we found that a tandem oxidative cyclization/epoxidation as an unexpected reaction proceeded in the presence of TEMPO as an additive. Intramolecular oxidative aminocyclization of homotryptamines at the C-2 position would give tetrahydropyridoindole, a common intermediate for both reactions. Control experiments suggested that while oxidative coupling with TBHP at the C-3 position might afford peroxyindolenines, a preferential electrophilic addition of TEMPO+, which might be generated in situ by the hypoiodite-catalyzed oxidation of TEMPO, at C-3 position followed by elimination and epoxidation might give epoxyindolenines. This serendipitous finding prompted us to develop a chemoselective divergent synthesis of peroxy- and epoxyindolenines by simple modification of the reaction conditions.

DOI： 10.1021/acs.orglett.0c03001

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

We report high-performance I+/H2O2 catalysis for the oxidative or decarboxylative oxidative α-azidation of carbonyl compounds by using sodium azide under biphasic neutral phase-transfer conditions. To induce higher reactivity especially for the α-azidation of 1,3-dicarbonyl compounds, we designed a structurally compact isoindoline-derived quaternary ammonium iodide catalyst bearing electron-withdrawing groups. The nonproductive decomposition pathways of I+/H2O2 catalysis could be suppressed by the use of a catalytic amount of a radical-trapping agent. This oxidative coupling tolerates a variety of functional groups and could be readily applied to the late-stage α-azidation of structurally diverse complex molecules. Moreover, we achieved the enantioselective α-azidation of 1,3-dicarbonyl compounds as the first successful example of enantioselective intermolecular oxidative coupling with a chiral hypoiodite catalyst.

DOI： 10.1002/anie.202007552

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

ortho-Quinone methides are useful transient synthetic intermediates in organic synthesis. These species are most often generated in situ by the acid- or base-mediated transformation of phenols that have been pre-functionalized at a benzylic position, or by biomimetic oxidation of the corresponding ortho-alkylphenols with metal oxidants or transition-metal complexes. Here we describe a method for the transition-metal-free oxidative generation of o-QMs from ortho-alkylarenols, using hypoiodite catalysis under nearly neutral conditions, which can then be applied in one-pot tandem reactions. This method for the chemoselective oxidative generation of ortho-quinone methides may prove superior to previous methods with respect to environmental issues and scope, and can be applied to various tandem reactions such as inter- or intramolecular [4 + 2] cycloaddition, oxa-6π-electrocyclization, conjugate addition and spiroepoxidation.

DOI： 10.1038/s41557-020-0433-4

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

We developed a chemoselective oxidative dearomative spiroetherification and spiroamination of arenols using I+/oxone catalysis. The intramolecular dearomative C–O and C–N couplings proceeded much more efficiently under slightly acidic conditions to give the corresponding spiro adducts in higher yields compared with previous methods using transition metal or hypervalent iodine catalysts. Control experiments suggested that both hypoiodous acid and iodine might be active species for these reactions.

DOI： 10.1021/acs.orglett.9b04324

Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)  

As the global issues of environment, energy, and natural resource scarcity increase, the development
of environmentally friendly and efficient catalytic methodologies of organic synthesis is strongly demanded for the sustainable advancement of material civilization. For this purpose, the use of toxic heavy metals and precious transition metals as reactants and/or catalysts should be avoided as much as possible in the synthesis of medicinal and pharmaceutical products. Over the past decades, iodine compounds have been the focus of great attention due to their mild and chemoselective oxidizing properties and their environmentally benign characteristics in contrast to
toxic metal oxidants. Furthermore, the development of chiral hypervalent iodine-catalyzed enantioselective oxidative transformation is one of the most challenging areas in asymmetric organocatalysis. Here, we demonstrate the rational
design of conformationally flexible chiral diamide-type C2-symmetric organoiodine catalysis based on secondary
nonbonding interactions for the enantioselective oxidative dearomatization of arenols. Several research groups
have also reported highly enantioselective oxidative transformations using these conformationally flexible chiral
organoiodine(III) catalysts or reagents. These examples highlight the substantial scope of conformationally flexible designer organoiodine(III) catalysis.

Authorship：Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

環境・エネルギー・資源問題が深刻化するなか，物質文明社会の持続的発展のためには，環境低負荷型触媒的精密有機合成法の開拓が有機合成化学の最重要課題の一つであり，遷移金属等のレアメタルや重金属等の毒性の強い金属資源を反応剤や触媒に用いる従来型の有機合成化学からの脱却が求められている。これに関連し近年，有毒な重金属酸化物の代替物質として超原子価ヨウ素化合物が注目されている。しかし，超原子価ヨウ素の化学は1世紀以上の長い歴史をもつにもかかわらず，不斉酸化反応の成功例はほとんどなく，不斉有機触媒の最も挑戦的な課題の一つとされていた。我々は，それまでの触媒設計概念とは全く異なる配座柔軟性に富むキラルヨードアレーンを分子設計した。本設計は，触媒活性中心（I(III)）と側鎖末端の間に適切な非共有結合性二次的相互作用を導入することで有効な不斉場を構築することを特徴とし，酵素反応に見られる誘導適合のような不斉誘導が可能となる。これらの柔軟かつ機能的な触媒は，様々な酸化的変換反応において世界中で利用されるようになってきている。本総説では我々のC 2対称ジアミド型触媒設計とその応用例について紹介する。

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

A high-performance enantioselective quaternary ammonium hypoiodite catalysis was developed for the dearomatization of arenols using oxone as an environmentally benign oxidant. The oxidation of not only 1- and 2-naphthols but also phenols, which were hardly reactive using the previous hypoiodite catalysis, readily proceeded under mild conditions, and only inorganic wastes were generated from the oxidant used. Control experiments and Raman analysis revealed the in situ generation of I+ such as hypoiodous acid as an unstable active species and molecular iodine (I2) as a stable dormant species. Most of the advantages of the present I+/oxone catalysis, compared to previous I+/(H2O2 or ROOH) systems, may result from generation of the stable dormant state and the higher reactivity of catalysts under acidic conditions.

DOI： 10.1021/acscatal.9b04322

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

The first transition metal-free catalytic oxidative dearomatizative azidation of arenols has been developed using hypoiodite catalysis with aqueous hydrogen peroxide and trimethylsilyl azide as an oxidant and azide source, respectively, under mild conditions. The corresponding quaternary azides can be obtained in high to excellent yields.

DOI： 10.1246/cl.181036

Language：English   Publishing type：Research paper (scientific journal)   Publisher：Wiley  

DOI： 10.1002/ejoc.201801769

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

We developed a practical and environmentally benign method for the chlorinative dearomatization of arenols using transient electrophilic chlorinating species generated in situ from inexpensive sodium chloride and Oxone as a Cl source and oxidant, respectively, under mild conditions. Moreover, the regioselective chlorination or chlorinative dearomatization of 1-naphthols was also achieved by changing the reaction conditions.

DOI： 10.1002/ejoc.201801063

Language：English   Publishing type：Research paper (scientific journal)  

The total synthesis of pestheic acid based on an intramolecular SNAr reaction without a nitro group and the asymmetric synthesis of (-)-maldoxin by a catalytic enantioselective oxidative dearomatization of pestheic acid are described. The reactivity of (-)-maldoxin as a diene in the Diels-Alder reaction is also investigated.

DOI： 10.1021/acs.orglett.8b01502

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

Highly enantioselective oxidative dearomatization of 2-naphthol derivatives was achieved for the first time by using conformationally flexible organoiodine catalysts derived from 2-aminoalcohol as a chiral source. Moreover, with the use of these catalysts, excellent enantioselectivities were also achieved for 1-naphthol derivatives, which had previously been obtained with only lower enantioselectivities. Furthermore, the product obtained from the present reaction could be transformed to a highly functionalized spirolactone in high yield and with excellent stereoselectivity.

DOI： 10.1021/acs.joc.7b01941

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

A site-selective hydroxylative dearomatization of 2-substituted phenols to either 1,2-benzoquinols or their cyclodimers, catalyzed by 4,5-dimethyl-2-iodoxybenzenesulfonic acid with Oxone, has been developed. Furthermore, both the reaction rate and site selectivity could be further improved by the introduction of a trialkylsilylmethyl substituent at the 2-position of phenols. The corresponding 1,2-quinols could be transformed into various useful structural motifs by [4+2] cycloaddition cascade reactions.

DOI： 10.1002/anie.201612463

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

Here, we report the first transition metal-free peroxidative dearomatization of phenols using hypoiodite catalysis with TBHP. Hypoiodite salts are generated in situ from the corresponding quaternary ammonium iodides in the presence of TBHP, and the oxidative coupling reaction proceeds efficiently under mild conditions. The dearomatized products are versatile synthetic intermediates for further synthetic transformations to various complex structures including heterocycles. As a demonstration, the further oxidation of the unsaturated peroxide with TBHP afforded the corresponding peroxy epoxide in good yield.

DOI： 10.3987/COM-16-S(S)84

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

A highly enantioselective oxidative dearomatization of ortho- and para-hydroquinone derivatives to the corresponding masked ortho- and para-benzoquinones has been achieved by using chiral organoiodine(III) catalysts.

DOI： 10.1021/acscatal.6b03380

Authorship：Lead author,　Corresponding author   Language：Japanese   Publishing type：Research paper (scientific journal)  

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

2-Acyl tetrahydrofuran is a fundamental structure in natural products and pharmaceuticals. We achieved a chiral quaternary ammonium hypoiodite salt-catalyzed enantioselective oxidative cycloetherification of δ-hydroxyketone derivatives. The corresponding 2-acyl tetrahydrofurans were obtained in high chemical yield with high enantioselectivity.

DOI： 10.1246/cl.160004

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

A highly efficient and practical oxidative dearomatization of phenols using sodium hypochlorite pentahydrate as an inexpensive, strong oxidant is reported for the first time. The oxidation reactions proceeded very rapidly in the presence of water to give the desired products in excellent yields, and sodium chloride and water were the only by-products derived from the oxidant.

DOI： 10.1246/cl.141130

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

Highly efficient hypoiodite-catalyzed oxylactonization of aliphatic γ-oxocarboxylic acids to the corresponding γ-acyl-γ-butyrolactones was developed. Highly dilute reaction conditions and slow addition of the oxidant are each highly effective for promoting the high-performance hypoiodite/hydrogen peroxide catalytic oxidation system.

DOI： 10.1246/cl.141110

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

A highly enantioselective oxidative dearomatization of 1-naphthol derivatives (Kita spirolactonization) catalyzed by chiral hypoiodite species prepared in situ from chiral quaternary ammonium iodide in the presence of hydrogen peroxide is reported.

DOI： 10.1246/cl.141012

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

The diverse biological activities of tocopherols and their analogs have inspired considerable interest in the development of routes for their efficient asymmetric synthesis. Here, we report that chiral ammonium hypoiodite salts catalyze highly chemo- and enantioselective oxidative cyclization of γ-(2-hydroxyphenyl)ketones to 2-acyl chromans bearing a quaternary stereocenter, which serve as productive synthetic intermediates for tocopherols. Raman spectroscopic analysis of a solution of tetrabutylammonium iodide and tert-butyl hydroperoxide revealed the in situ generation of the hypoiodite salt as an unstable catalytic active species and triiodide salt as a stable inert species. A high-performance catalytic oxidation system (turnover number of ~200) has been achieved through reversible equilibration between hypoiodite and triiodide in the presence of potassium carbonate base. We anticipate that these findings will open further prospects for the development of high-turnover redox organocatalysis.

DOI： 10.1126/science.1254976

Authorship：Lead author   Language：Japanese   Publishing type：Research paper (conference, symposium, etc.)  

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

A conformationally flexible C2-symmetric organoiodine(III) catalyst for the highly enantioselective catalytic oxidative dearomatization of phenols has been developed. Catalysis is controlled by intramolecular hydrogen-bonding interactions and additional achiral alcohols.

DOI： 10.1002/anie.201303559

Authorship：Lead author   Language：English  

The Baeyer-Villiger (BV) oxidation of carbonyl compounds to the corresponding esters or lactones is one of the most important transformations. We recently introduced a highly efficient and selective LiB(C6F5)4- or Ca[B(C6F5)4]2-catalyzed BV oxidation of ketones with aqueous hydrogen peroxide to give the corresponding lactones in high yield. In this perspective article, we focus on our discovery and the development of BV oxidation reactions and cascade oxidative transformations through representative metal catalysts and organocatalysts.

DOI： 10.1021/cs300821u

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

The development of chiral hypervalent iodine-catalyzed oxidative transformations is one of the most challenging areas in asymmetric organocatalysis. Although several elegant chiral hypervalent iodine(III and V) reagents or catalysts had been developed for various asymmetric oxidation reactions, the enantioselectivities had been moderate before our paper was published in 2010. We have had a great interest in the development of organocatalysis based on hypervalent chemistry since 2007. In this account, we describe our design concept of conformationally-flexible chiral hypervalent organoiodine(III), and the results obtained for catalytic use of our chiral iodines(III) for enantioselective Kita oxidative spirolactonization. Additionally, other chiral hypervalent iodine-mediated asymmetric oxidation reactions reported after our publications are also highlighted briefly.

DOI： 10.5059/yukigoseikyokaishi.70.1116

Web of Science

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

We have developed highly efficient and selective Li[B(C6F5)4] or Ca[B(C6F5)4]2 catalyzed Baeyer-Villiger (BV) oxidations of various cycloalkanones with 30-wt% aqueous hydrogen peroxide to give the corresponding lactones in high yield. Additionally, we have found that the reaction rate is accelerated with the use of oxalic acid as a co-catalyst. Moreover, beta-silyl cyclohexanones can be oxidized to either the corresponding unsaturated carboxylic acids or hydroxylactones in high yields through BV oxidation/b-elimination reaction sequences and subsequent epoxidation/cyclization reaction sequences, by controlling the amounts of H2O2 and oxalic acid. These reactions proceed under mild conditions and tolerate various functional groups.

DOI： 10.1002/anie.201204286

Authorship：Lead author   Language：Japanese   Publishing type：Research paper (bulletin of university, research institution)  

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

We have developed the first example of hypervalent iodine(V)-catalyzed regioselective oxidation of phenols to ortho-quinones. Various phenols could be oxidized to the corresponding ortho-quinones in good to excellent yields using catalytic amounts of sodium salts of 2-iodobenzenesulfonic acids (pre-IBSes) and stoichiometric amounts of Oxone as a co-oxidant under mild conditions. The reaction rate of IBS-catalyzed oxidation under nonaqueous conditions was further accelerated in the presence of an inorganic base such as potassium carbonate (K2CO3), a phase transfer catalyst such as tetrabutylammonium hydrogen sulfate (n-Bu4NHSO4), and a dehydrating agent such as anhydrous sodium sulfate (Na2SO4).

DOI： 10.3390/molecules17078604

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

This Concept highlights the discovery and development of oxidative coupling reactions catalyzed by the hypoiodite (IO) or iodite (IO2) ion, which are generated in situ from iodide (I-) ion with hydrogen peroxide or tert-butyl hydroperoxide as an environmentally benign oxidant. The most important features of these catalytic systems are 1) metal-free oxidation, 2) milder reaction conditions, 3) high chemoselectivity (they tolerate a wide range of various functional groups), 4) operational simplicity, and 5) water or tert-butyl alcohol as the only byproduct derived from the co-oxidant used.

DOI： 10.1002/cctc.201100352

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

We have reported that 2-iodoxybenzenesulfonic acids (IBSs) which are in situ prepared from Oxone and 2-iodobenzenesulfonic acids show efficient catalytic activity on the alcohol oxidation under mild conditions. Here, we succeeded in scale up of the IBS-catalyzed alcohol oxidations.

DOI： 10.15227/orgsyn.089.0105

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

The intra- and intermolecular title reaction is catalyzed by an in situ generated ammonium (hypo)iodite species. Either H2O2 or tert-butyl hydroperoxide (TBHP) can be used as an environmentally benign oxidant and a wide range of substrates react to give the corresponding alpha-acyloxycarbonyl compounds in good to excellent yields.

DOI： 10.1002/anie.201101522

Authorship：Lead author   Language：Japanese  

Authorship：Lead author   Language：English  

Very recently, we developed the first enantioselective oxidative cycloetherification of ketophenols to 2-acyl-2,3-dihydrobenzofuran derivatives catalysed by in situ generated chiral quaternary ammonium (hypo)iodite with hydrogen peroxide or tert-butyl hydroperoxide (TBHP) as an environmentally benign ideal oxidant. The optically active
2-acyl 2,3-dihydrobenzofuran skeleton is a key structure in
several medicinally and biologically active compounds.

Language：English   Publishing type：Research paper (scientific journal)  

The oxidation of alcohols to the corresponding carbonyl compounds is one of the most important transformations in synthetic organic chemistry. Over the past two decades, hypervalent iodine compounds have received a great deal of attention due to their mild and chemoselective oxidizing properties and to the fact that, unlike toxic heavy-metal-based reagents, they are environmentally benign. We recently published a review on the oxidation of alcohols with stoichiometric or catalytic hypervalent iodine compounds. The present review focuses on the discovery and development of 2-iodoxybenzenesulfonic acid (IBS) and related hypervalent iodine compounds. It also covers advances in hypervalent iodine catalyzed alcohol oxidations and related transformations reported between 2005 and 2010.

Language：Japanese   Publishing type：Research paper (conference, symposium, etc.)  

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

It is desirable to minimize the use of rare or toxic metals for oxidative reactions in the synthesis of pharmaceutical products. Hypervalent iodine compounds are environmentally benign alternatives, but their catalytic use, particularly for asymmetric transformations, has been quite limited. We report here an enantioselective oxidative cycloetherification of ketophenols to 2-acyl-,3-dihydrobenzofuran derivatives, catalyzed by in situ generated chiral quaternary ammonium (hypo)iodite salts, with hydrogen peroxide as an environmentally benign oxidant. The optically active 2-acyl 2,3-dihydrobenzofuran skeleton is a key structure in several biologically active compounds.

DOI： 10.1126/science.1188217

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

We demonstrate here the rational design of a conformationally flexible C2-symmetric iodosylarene 8g based on secondary n-sigma* or hydrogen-bonding interactions as a chiral catalyst for the enantioselective Kita oxidative spirolactonization of 1-naphthol derivatives 5. Iodosylarenes 8 were generated in situ from iodoarenes 7 and mCPBA as a co-oxidant. Furthermore, epoxyspirolactone 15 was obtained by the one-pot oxidation of 5 with mCBPA in the presence of 7g. Thus, the enantioselective oxidation of 5 to 6 and the successive enantio- and diastereo-selective oxidation of 5 to 15 proceeded in good yields when we controlled the amount of mCPBA.

DOI： 10.1016/j.tet.2010.04.060

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

Conformationally flexible C2-symmetric chiral iodosylarene, which has been rationally designed based on secondary n-σ* or hydrogen-bonding interactions, is a highly effective catalyst for the Kita oxidative spirolactonization. The present catalysis is applicable to a broader range of substrates and provides the highest enantioselectivity (up to 92% ee) among previous chiral hypervalent iodine-catalyzed reactions.

DOI： 10.1002/anie.200907352

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

We demonstrated that a simple and environmentally benign catalytic system HBr/NaNO2 is very effective for the selective oxidation of alcohols under balloon pressure of O2. Furthermore, the aerobic oxidation of alcohols was also achieved under balloon pressure of air instead of pure O2 with this HBr/NaNO2/HNO3 catalytic system.

DOI： 10.1002/asia.200900609

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

A 2-iodoxybenzenesulfonic acid (IBS)-catalyzed oxidative rearrangement of tertiary allylic alcohols to enones with powdered Oxone in the presence of potassium carbonate and tetrabutylammonium hydrogen sulfate has been developed.

DOI： 10.1021/ol9013188

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

The hypervalent iodine-catalyzed oxylactonization of ketocarboxylic acids to ketolactones was achieved in the presence of iodobenzene (10 mol%), p-toluenesulfonic acid monohydrate (20 mol%) and meta-chloroperbenzoic acid as a stoichiometric co-oxidant.

DOI： 10.1016/j.bmcl.2009.03.148

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

Over the past two decades there has been a dramatic increse in the use of hypervalent iodine compounds in synthetic organic chemistry due to their mild and selective oxidizing properties. Hypervalent iodine compounds catalyze various oxidation reactions such as the oxidation of alcohols, alpha-oxidation of ketones, oxidative spirocyclization of phenols, etc. Very recently, we found that 2-iodoxybenzensulfonic acid (IBS), which was generated from 2-iodobenzenesulfonic acid in situ, was an extremely active and mild catalyst for the highly chemoselective oxidation of various alcohols with powdered Oxone to carbonyl compounds such as aldehydes, carboxylic acids, ketones and cycloalkenones under nonaqueous conditions. In this review, we focus on the design of hypervalent iodine catalysts and review the discovery and development of the oxidation of alcohols with the stoichiometric or catalytic use of hypervalent iodine compounds.

DOI： 10.1039/b823399c

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

Electron-donating group-substituted 2-iodoxybenzoic acids (IBXs) were superior to IBX as catalysts for the oxidation of alcohols with Oxone under nonaqueous conditions. Furthermore, 2-iodoxybenzenesulfonic acid (IBS) was much more active than modified IBXs. Thus, we established a highly efficient and selective method for the oxidation of primary and secondary alcohols to carbonyl compounds such as aldehydes, carboxylic acids, and ketones with Oxone in nonaqueous nitromethane, acetonitrile, or ethyl acetate in the presence of 0.05-5 mol % of IBS, which was generated in situ from 2-iodobenzenesulfonic acid or its sodium salt. Cycloalkanones could be further oxidized to α,β-cycloalkenones or lactones by controlling the amounts of Oxone under the same conditions as above. Based on theoretical calculations, we considered that the relatively ionic character of the intramolecular hypervalent iodine-OSO2 bond of IBS might lower the twisting barrier of the alkoxyperiodinane intermediate.

DOI： 10.1021/ja807110n

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

Highly diastereoselective polycyclization of homo(polyprenyl)arene analogues bearing terminal siloxyvinyl groups was catalyzed by tin(IV) chloride (10 mol %). The cyclizations of tert-butyldiphenylsilyl and triisopropylsilyl polyenol ethers gave 4(equatorial)- and 4(axial)-siloxypolycycles as major isomers, respectively. The strong nucleophilicity of pro-C(9), a (6E) geometry, and a bulky silyl group effectively favored the 4-preference, whereas the weak nucleophilicity of pro-C(9), a (6Z)-geometry, and less steric hindrance of a silyl group favored the 4-preference.

DOI： 10.1021/ol062378t

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

Asymmetric total syntheses of acid-sensitive (-)- and (+)-caparrapi oxides (1) and (+)-8-epicaparrapi oxide (2) from farnesol (10) are achieved using Sharpless-Katsuki epoxidation and Lewis acid-assisted chiral Br?nsted acid (chiral LBA)-induced polyene cyclization as key steps. The relative configuration of (+)-dysifragin (4) is determined by a single-crystal X-ray diffraction and its total synthesis is accomplished by the diastereoselective epoxidation of (+)-1. Furthermore, (-)-1 can be directly synthesized from (S)-nerolidol (3) and (R)-LBA with 88% ds by reagent control, which overcame substrate control, while (-)-2 is obtained from (R)-3 and (R)-LBA with >99% ds by the double asymmetric induction.

DOI： 10.1016/j.bmc.2005.04.029

Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)  

Asymmetric total syntheses of acid-sensitive (-)-caparrapi oxide (1) and (+)-8-epicaparrapi oxide (2) from farnesol (9) were achieved using Sharpless-Katsuki epoxidation and Lewis acid-assisted chiral Brnsted acid (chiral LBA)-induced polyene cyclization as key steps. Furthermore, (-)-1 could be directly synthesized from (S)-nerolidol (3) and (R)-LBA with 88% ds by reagent control which overcame substrate control, while (-)-2 was obtained from (R)-3 and (R)-LBA with >99% ds by the double-asymmetric induction.

DOI： 10.1021/o1050295r

Total pages：9806   Responsible for pages：pp. 573–597   Language：English Book type：Scholarly book

DOI： 10.1016/B978-0-08-097742-3.00622-4

Other Link： https://www.amazon.com/Comprehensive-Organic-Synthesis-Paul-Knochel/dp/0080977421

Total pages：782   Responsible for pages：pp. 332-338   Language：English Book type：Scholarly book

DOI： 10.1002/047084289X.rn01214.pub2

Other Link： https://www.amazon.com/Catalytic-Oxidation-Reagents-Philip-Fuchs-dp-1119953278/dp/1119953278/ref=mt_hardcover?_encoding=UTF8&me=&qid=1568807612

Total pages：782   Responsible for pages：pp. 32-48   Language：English Book type：Scholarly book

DOI： 10.1002/047084289X.rn00236.pub2

Event date： 2018.11

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Venue：Kyoto University, Kyoto   Country：Japan  

Event date： 2017.12

Language：English   Presentation type：Oral presentation (invited, special)  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2017.11

Language：English   Presentation type：Poster presentation  

Venue：Skypark Hotel, Nagano   Country：Japan  

Event date： 2017.9

Language：English   Presentation type：Oral presentation (invited, special)  

Venue：Meitetsu Inuyama Hotel, Inuyama   Country：Japan  

Event date： 2017.3

Language：English   Presentation type：Oral presentation (invited, special)  

Venue：Hiyoshi Campus, Keio University, Yokohama   Country：Japan  

Event date： 2017.2

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Venue：岡山大学、岡山   Country：Japan  

Event date： 2016.12

Language：English   Presentation type：Oral presentation (invited, special)  

Venue：Chiba University, Chiba   Country：Japan  

Event date： 2016.2

Language：English   Presentation type：Oral presentation (invited, special)  

Country：Japan  

Event date： 2015.6

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Country：Japan  

Event date： 2015.3

Language：English   Presentation type：Oral presentation (invited, special)  

Country：Turkey  

Event date： 2014.7

Language：English   Presentation type：Oral presentation (invited, special)  

Country：Canada  

Event date： 2014.6

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Country：Japan  

Event date： 2014.1

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Country：Japan  

Event date： 2013.11

Language：English   Presentation type：Oral presentation (invited, special)  

Country：Japan  

Event date： 2013.3

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Country：Japan  

Event date： 2012.4

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Country：Japan  

Event date： 2012.3

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Country：Japan  

Event date： 2012.3

Language：English   Presentation type：Oral presentation (invited, special)  

Country：Japan  

Event date： 2011.6 - 2011.7

Language：English   Presentation type：Oral presentation (invited, special)  

Country：Turkey  

Event date： 2010.10

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Country：Japan  

Event date： 2024.3

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2024.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Funabashi Campus, Nihon University   Country：Japan  

Event date： 2024.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Funabashi Campus, Nihon University   Country：Japan  

Event date： 2024.3

Presentation type：Oral presentation (general)  

Venue：Funabashi Campus, Nihon University   Country：Japan  

Event date： 2024.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Funabashi Campus, Nihon University   Country：Japan  

Event date： 2024.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Funabashi Campus, Nihon University   Country：Japan  

Event date： 2024.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Funabashi Campus, Nihon University   Country：Japan  

Event date： 2024.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Funabashi Campus, Nihon University   Country：Japan  

Event date： 2024.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Funabashi Campus, Nihon University   Country：Japan  

Event date： 2024.1

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2024.1

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2024.1

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2024.1

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2023.11

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2023.11

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2023.11

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2023.11

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2023.10

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2023.10

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2023.10

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2023.9

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2023.9

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2023.9

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2023.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2023.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2023.6

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2023.6

Language：English   Presentation type：Oral presentation (invited, special)  

Country：Sweden  

Event date： 2023.6

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2023.6

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2023.3

Language：English   Presentation type：Oral presentation (general)  

Venue：Noda Campus, Tokyo University of Science   Country：Japan  

Event date： 2023.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Noda Campus, Tokyo University of Science   Country：Japan  

Event date： 2023.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Noda Campus, Tokyo University of Science   Country：Japan  

Event date： 2023.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Noda Campus, Tokyo University of Science   Country：Japan  

Event date： 2023.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Noda Campus, Tokyo University of Science   Country：Japan  

Event date： 2023.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Noda Campus, Tokyo University of Science   Country：Japan  

Event date： 2023.1

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2022.11

Language：English   Presentation type：Poster presentation  

Venue：Kazusa Arc, Kisarazu, Chiba   Country：Japan  

Event date： 2022.11

Language：Japanese   Presentation type：Poster presentation  

Venue：Online   Country：Japan  

Event date： 2022.11

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Online   Country：Japan  

Event date： 2022.10

Language：Japanese   Presentation type：Poster presentation  

Venue：Tower Hall Funabori, Tokyo   Country：Japan  

Event date： 2022.10

Language：Japanese   Presentation type：Poster presentation  

Venue：Tower Hall Funabori, Tokyo   Country：Japan  

Event date： 2022.10

Language：Japanese   Presentation type：Poster presentation  

Venue：Tower Hall Funabori, Tokyo   Country：Japan  

Event date： 2022.6

Language：Japanese   Presentation type：Poster presentation  

Venue：Awaji Yumebutai International Conference Center, Hyogo   Country：Japan  

Event date： 2022.6

Language：Japanese   Presentation type：Poster presentation  

Venue：Awaji Yumebutai International Conference Center, Hyogo   Country：Japan  

Event date： 2022.6

Language：Japanese   Presentation type：Poster presentation  

Venue：Awaji Yumebutai International Conference Center, Hyogo   Country：Japan  

Event date： 2022.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2022.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2022.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2022.3

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2022.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2022.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2022.3

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2022.1

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2021.10

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2021.10

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2021.10

Language：Japanese   Presentation type：Poster presentation  

Event date： 2021.10

Language：Japanese   Presentation type：Oral presentation (general)  

Event date： 2021.9

Language：Japanese   Presentation type：Poster presentation  

Event date： 2021.9

Language：Japanese   Presentation type：Poster presentation  

Event date： 2021.7

Language：English   Presentation type：Oral presentation (general)  

Event date： 2021.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2021.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2021.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2021.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2021.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2021.3

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2021.1

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2021.1

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2020.10

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2020.10

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2020.3

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2020.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2020.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2020.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2020.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2020.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2020.3

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2020.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2020.1

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2020.1

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2019.12

Language：Japanese   Presentation type：Poster presentation  

Venue：Kyoto University   Country：Japan  

Event date： 2019.11

Language：Japanese   Presentation type：Poster presentation  

Venue：Shinshu University Matsumoto Campus, Nagano   Country：Japan  

Event date： 2019.10

Language：Japanese   Presentation type：Poster presentation  

Venue：Tower Hall Funabori, Tokyo   Country：Japan  

Event date： 2019.10

Language：Japanese   Presentation type：Poster presentation  

Venue：Tower Hall Funabori, Tokyo   Country：Japan  

Event date： 2019.9

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagarawa Convention Center, Gifu   Country：Japan  

Event date： 2019.9

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagarawa Convention Center, Gifu   Country：Japan  

Event date： 2019.9

Language：English   Presentation type：Poster presentation  

Venue：Miyako Messe, Kyoto   Country：Japan  

Event date： 2019.9

Language：English   Presentation type：Poster presentation  

Venue：Miyako Messe, Kyoto   Country：Japan  

Event date： 2019.8

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2019.8

Language：Japanese   Presentation type：Poster presentation  

Venue：Chiba University, Chiba   Country：Japan  

Event date： 2019.7

Language：Japanese   Presentation type：Poster presentation  

Venue：Jozankei Onsen Hotel Shikanoyu, Sapporo   Country：Japan  

Event date： 2019.6 - 2019.7

Language：Japanese   Presentation type：Poster presentation  

Venue：Marine Lodge Kaifukan, Osaka   Country：Japan  

Event date： 2019.6

Language：Japanese   Presentation type：Poster presentation  

Venue：Setouchi Kojima Hotel, Kurashiki, Okayama   Country：Japan  

Event date： 2019.6

Language：Japanese   Presentation type：Poster presentation  

Venue：Setouchi Kojima Hotel, Kurashiki, Okayama   Country：Japan  

Event date： 2019.6

Language：Japanese   Presentation type：Poster presentation  

Venue：Suzuka Circuit, Mie   Country：Japan  

Event date： 2019.6

Language：Japanese   Presentation type：Poster presentation  

Venue：Suzuka Circuit, Mie   Country：Japan  

Event date： 2019.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Konan University (Okamoto Campus), Hyogo   Country：Japan  

Event date： 2019.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Konan University (Okamoto Campus), Hyogo   Country：Japan  

Event date： 2019.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Konan University (Okamoto Campus), Hyogo   Country：Japan  

Event date： 2019.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Konan University (Okamoto Campus), Hyogo   Country：Japan  

Event date： 2019.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Konan University (Okamoto Campus), Hyogo   Country：Japan  

Event date： 2019.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Konan University (Okamoto Campus), Hyogo   Country：Japan  

Event date： 2019.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Konan University (Okamoto Campus), Hyogo   Country：Japan  

Event date： 2019.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Konan University (Okamoto Campus), Hyogo   Country：Japan  

Event date： 2019.1

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2019.1

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2019.1

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2019.1

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2018.12

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2018.11

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2018.11

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2018.10

Language：Japanese   Presentation type：Poster presentation  

Venue：Tower Hall Funabori, Tokyo   Country：Japan  

Event date： 2018.10

Language：Japanese   Presentation type：Poster presentation  

Venue：Tower Hall Funabori, Tokyo   Country：Japan  

Event date： 2018.9

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2018.8 - 2018.9

Language：English   Presentation type：Poster presentation  

Venue：Keio University, Hiyoshi Campus, Yokohama   Country：Japan  

Event date： 2018.7

Language：Japanese   Presentation type：Poster presentation  

Venue：Ikeda, Osaka   Country：Japan  

Event date： 2018.7

Language：Japanese   Presentation type：Poster presentation  

Venue：Ikeda, Osaka   Country：Japan  

Event date： 2018.7

Language：Japanese   Presentation type：Poster presentation  

Venue：Kyoto   Country：Japan  

Event date： 2018.6

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Sakata-Hirata Hall   Country：Japan  

Event date： 2018.6

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Sakata-Hirata Hall   Country：Japan  

Event date： 2018.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Nihon University Funabashi Campus, Chiba   Country：Japan  

Event date： 2018.3

Language：English   Presentation type：Oral presentation (general)  

Venue：Nihon University Funabashi Campus, Chiba   Country：Japan  

Event date： 2018.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Nihon University Funabashi Campus, Chiba   Country：Japan  

Event date： 2018.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Nihon University Funabashi Campus, Chiba   Country：Japan  

Event date： 2018.3

Language：English   Presentation type：Oral presentation (general)  

Venue：Nihon University Funabashi Campus, Chiba   Country：Japan  

Event date： 2018.3

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Nihon University Funabashi Campus, Chiba   Country：Japan  

Event date： 2018.3

Language：English   Presentation type：Oral presentation (general)  

Venue：Nihon University Funabashi Campus, Chiba   Country：Japan  

Event date： 2018.1

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2018.1

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2018.1

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2017.11

Language：English   Presentation type：Poster presentation  

Venue：Nanyang Technological University, Singapore   Country：Singapore  

Event date： 2017.10

Language：Japanese   Presentation type：Poster presentation  

Venue：Tower Hall Funabori, Tokyo   Country：Japan  

Event date： 2017.10

Language：Japanese   Presentation type：Oral presentation (general)  

Venue：Tower Hall Funabori, Tokyo   Country：Japan  

Event date： 2017.9

Language：English   Presentation type：Poster presentation  

Venue：Meitetsu Inuyama Hotel, Inuyama   Country：Japan  

Event date： 2017.9

Language：English   Presentation type：Poster presentation  

Venue：Meitetsu Inuyama Hotel, Inuyama   Country：Japan  

Event date： 2017.9

Language：English   Presentation type：Poster presentation  

Venue：Meitetsu Inuyama Hotel, Inuyama   Country：Japan  

Event date： 2017.9

Language：English   Presentation type：Poster presentation  

Venue：Meitetsu Inuyama Hotel, Inuyama   Country：Japan  

Event date： 2017.9

Language：Japanese   Presentation type：Poster presentation  

Venue：Chiba University, Chiba   Country：Japan  

Event date： 2017.8

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2017.8

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2017.7

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2017.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2017.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2017.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2017.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2017.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2017.3

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2017.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2017.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2017.1

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2016.11

Language：Japanese   Presentation type：Poster presentation  

Venue：Toyohashi University of Technology, Aichi   Country：Japan  

Event date： 2016.10

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2016.9

Language：Japanese   Presentation type：Poster presentation  

Venue：Chiba University, Chiba   Country：Japan  

Event date： 2016.8

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2016.7

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya Congress Center, Aichi   Country：Japan  

Event date： 2016.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2016.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2016.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2016.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2016.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2016.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2016.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2016.3

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2016.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2016.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2016.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2016.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2016.3

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2016.1

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2016.1

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2015.11

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2015.11

Language：Japanese   Presentation type：Poster presentation  

Venue：分子科学研究所（岡崎）   Country：Japan  

Event date： 2015.11

Language：Japanese   Presentation type：Poster presentation  

Venue：分子科学研究所（岡崎）   Country：Japan  

Event date： 2015.9

Language：Japanese   Presentation type：Poster presentation  

Venue：Nagoya University, Nagoya   Country：Japan  

Event date： 2015.9

Language：Japanese   Presentation type：Poster presentation  

Venue：名古屋大学   Country：Japan  

Event date： 2015.7

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2015.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2015.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2015.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2015.6

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.6

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.3

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2015.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.3

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2015.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2014.11

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2014.9

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2014.9

Language：Japanese   Presentation type：Oral presentation (invited, special)  

Country：Japan  

Event date： 2014.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2014.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2014.7

Language：English   Presentation type：Oral presentation (general)  

Country：Canada  

Event date： 2014.7

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2014.7

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2014.7

Language：English   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2014.7

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2014.7

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2014.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2014.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2014.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2014.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2014.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2014.3

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2014.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2014.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2014.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2014.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2014.1

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2014.1

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2014.1

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2014.1

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.11

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.10

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.10

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.9

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.5

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.5

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.5

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2013.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2013.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2013.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2013.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2013.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2013.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2013.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2013.1

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.1

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.1

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.1

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2013.1

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2012.12

Language：English   Presentation type：Poster presentation  

Country：Singapore  

Event date： 2012.11

Language：English   Presentation type：Poster presentation  

Country：Japan  

Event date： 2012.11

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2012.10

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2012.9

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2012.9

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2012.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2012.7

Language：English   Presentation type：Poster presentation  

Country：United States  

Event date： 2012.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2012.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2012.7

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2012.6

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2012.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2012.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2012.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2012.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2012.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2012.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2011.11

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2011.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2011.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2011.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2011.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2011.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2011.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2010.12

Language：English   Presentation type：Oral presentation (general)  

Country：United States  

Event date： 2010.11

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

Event date： 2010.11

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2010.11

Language：Japanese   Presentation type：Poster presentation  

Country：Japan  

Event date： 2010.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

A ketodihydrobenzofuran is a key skeketone of many biologically active compounds. The efficient synthetic method for those cycloethers is required. We succeeded in chiral hypervalent iodine catalyzed intramolecular oxidative cyclization of the ketophenols to the ketodihydrobenzofurans. Hypervalent iodine is generated in situ from a chiral ammonium iodide and hydrogen peroxide or tert-butyl hydroperoxide as co-oxidant.

Event date： 2010.3

Language：Japanese   Presentation type：Oral presentation (general)  

Country：Japan  

We succeeded in hypervalent iodine catalyzed intermolecular oxidative coupling of ketones and carboxylic acids to the corresponding α-acyloxy ketones in high yield. Hypervalent iodine is generated in situ from quaternary ammonium iodide and tert-butyl hydroperoxide (TBHP) as co-oxidant.

Event date： 2010.3

Language：Japanese   Presentation type：Oral presentation (general)