Updated on 2024/04/11

写真a

 
SUGIYAMA Shigeaki
 
Organization
Graduate School of Medicine Center for Research of Laboratory Animals and Medical Research Engineering Division for Advanced Medical Research Assistant Professor
Undergraduate School
School of Medicine Department of Medicine
Title
Assistant Professor
Contact information
メールアドレス

Degree 2

  1. 博士(医学) ( 2024.3   九州大学 ) 

  2. 修士(医科学) ( 2019.3   九州大学 ) 

Education 3

  1. Kyushu University

    2019.4 - 2023.3

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    Country: Japan

  2. Kyushu University

    2017.4 - 2019.3

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    Country: Japan

  3. Kyoto University

    2013.4 - 2017.3

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    Country: Japan

 

Papers 6

  1. Identification of effective CCR2 inhibitors for cancer therapy using humanized mice Reviewed

    Sugiyama, Shigeaki; Yumimoto, Kanae; Fujinuma, Shun; Nakayama, Keiichi I.

    Journal of Biochemistry   Vol. 175 ( 2 ) page: 195 - 204   2024.2

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    Authorship:Lead author   Language:English   Publishing type:Doctoral thesis  

    DOI: 10.1093/jb/mvad086

  2. Modulation of host glutamine anabolism enhances the sensitivity of small cell lung cancer to chemotherapy Reviewed

    Kodama, Manabu; Toyokawa, Gouji; Sugahara, Osamu; Sugiyama, Shigeaki; Haratake, Naoki; Yamada, Yuichi; Wada, Reona; Takamori, Shinkichi; Shimokawa, Mototsugu; Takenaka, Tomoyoshi; Tagawa, Tetsuzo; Kittaka, Hiroki; Tsuruda, Takeshi; Tanaka, Kentaro; Komatsu, Yushiro; Nakata, Keisuke; Imado, Yuri; Yamazaki, Koji; Okamoto, Isamu; Oda, Yoshinao; Takahashi, Masatomo; Izumi, Yoshihiro; Bamba, Takeshi; Shimizu, Hideyuki; Yoshizumi, Tomoharu; Nakayama, Keiichi I.

    Cell Reports   Vol. 42 ( 8 )   2023.8

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.celrep.2023.112899

  3. FOXK1 promotes nonalcoholic fatty liver disease by mediating mTORC1-dependent inhibition of hepatic fatty acid oxidation Reviewed

    Fujinuma, Shun; Nakatsumi, Hirokazu; Shimizu, Hideyuki; Sugiyama, Shigeaki; Harada, Akihito; Goya, Takeshi; Tanaka, Masatake; Kohjima, Motoyuki; Takahashi, Masatomo; Izumi, Yoshihiro; Yagi, Mikako; Kang, Dongchon; Kaneko, Mari; Shigeta, Mayo; Bamba, Takeshi; Ohkawa, Yasuyuki; Nakayama, Keiichi I.

    Cell Reports   Vol. 42 ( 5 )   2023.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1016/j.celrep.2023.112530

  4. Molecular evolution of Keap1 was essential for adaptation of vertebrates to terrestrial life Reviewed

    Yumimoto, Kanae; Sugiyama, Shigeaki; Motomura, Saori; Takahashi, Daisuke; Nakayama, Keiichi I.

    Science Advances   Vol. 9 ( 20 )   2023.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1126/sciadv.adg2379

  5. Potentials of C-C motif chemokine 2–C-C chemokine receptor type 2 blockers including propagermanium as anticancer agents Reviewed

    Yumimoto, Kanae; Sugiyama, Shigeaki; Mimori, Koshi; Nakayama, Keiichi I.

    Cancer Science   Vol. 110 ( 7 ) page: 2090 - 2099   2019.5

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1111/cas.14075

  6. SCFFbxw7 ubiquitylates KLF7 for degradation in a manner dependent on GSK-3-mediated phosphorylation Reviewed

    Sugiyama, Shigeaki; Yumimoto, Kanae; Inoue, Ippei; Nakayama, Keiichi I.

    Genes to Cells   Vol. 24 ( 5 ) page: 354 - 365   2019.3

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    Authorship:Lead author   Language:English  

    DOI: 10.1111/gtc.12680

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Books 3

  1. 論文図表を読む作法

    杉山成明( Role: Contributor ,  「タンパク質半減期測定」「ユビキチン化アッセイ」)

    羊土社  2022.6 

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    Language:Japanese Book type:Textbook, survey, introduction

  2. 実験医学

    木藤有紀、杉山成明、中山敬一( Role: Contributor ,  c-Mycのユビキチン化制御機構とがん幹細胞における役割)

    羊土社  2018.2 

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    Responsible for pages:508-513   Language:Japanese Book type:Textbook, survey, introduction

  3. 日本臨牀

    杉山成明、弓本佳苗、中山敬一( Role: Contributor ,  がんの浸潤と転移のメカニズム)

    日本臨牀社  2017.11 

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    Responsible for pages:125-129   Language:Japanese Book type:Textbook, survey, introduction

Presentations 6

  1. 前転移ニッチにおけるCD25- Treg細胞の機能解析

    杉山成明、弓本佳苗、中山敬一

    日本分子生物学会年会2023  2023.12.8 

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    Event date: 2023.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:神戸   Country:Japan  

  2. 原発腫瘍が転移巣の微小環境に及ぼす抑制的作用の解析

    杉山成明、弓本佳苗、久保田晋平、高橋恵生、宮園浩平、中山敬一

    日本分子生物学会年会2022  2022.12.1 

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    Event date: 2022.11 - 2022.12

    Venue:千葉   Country:Japan  

  3. 原発腫瘍によって誘導される転移抑制的な微小環境の解析

    杉山成明、弓本佳苗、久保田晋平、高橋恵生、宮園浩平、中山敬一

    日本分子生物学会年会2021  2021.12.2 

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    Event date: 2021.12

    Language:Japanese   Presentation type:Poster presentation  

    Venue:横浜   Country:Japan  

  4. Formation of a lymphocyte-independent anti-metastatic environment in the lung. International conference

    Sugiyama S, Yumimoto K, Wada R. Nakayama KI.

    Cell Symposia Hallmarks of Cancer  2019.11.19 

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    Event date: 2019.11

    Language:English   Presentation type:Poster presentation  

    Country:United States  

  5. 初期転移巣をターゲットとしたPETプローブの開発と薬剤スクリーニング

    杉山成明、弓本佳苗、中山敬一

    新学術領域研究「ネオ・セルフの生成・機能・構造」第4回領域班会議  2019.1.10 

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    Event date: 2019.1

    Language:Japanese   Presentation type:Oral presentation (general)  

    Venue:静岡   Country:Japan  

  6. 初期転移巣をターゲットとしたPETプローブの開発と薬剤スクリーニング

    杉山成明、弓本佳苗、中山敬一

    新学術領域研究予防を科学する炎症細胞社会学第1回領域班会議  2018.5.14 

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    Event date: 2018.5

    Language:Japanese   Presentation type:Poster presentation  

    Venue:富山   Country:Japan  

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KAKENHI (Grants-in-Aid for Scientific Research) 2

  1. 前転移肺に蓄積するCD25陰性Treg細胞を標的とした汎用的ながん転移予防法の開発

    Grant number:24K10288  2024.4 - 2027.3

    日本学術振興会(JSPS)  科学研究費助成事業(KAKEN)  基盤研究(C)

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    Authorship:Principal investigator 

    Grant amount:\4550000 ( Direct Cost: \3500000 、 Indirect Cost:\1050000 )

  2. 原発腫瘍が肺につくる転移抑制性環境の解析

    Grant number:21J10770  2021.4 - 2022.3

    日本学術振興会(JSPS)  科学研究費助成事業(KAKEN)  特別研究員奨励費

    杉山成明

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    Authorship:Principal investigator 

    Grant amount:\1700000 ( Direct Cost: \1700000 )