研究者詳細 - 須賀　英隆

論文 - 須賀　英隆

分割表示 >> ／全件表示 98 件中 1 - 98 件目

Simplified drug efficacy evaluation system for vasopressin neurodegenerative disease using mouse disease-specific induced pluripotent stem cells. 査読有り

Miwata T, Suga H, Mitsumoto K, Zhang J, Hamada Y, Sakakibara M, Soen M, Ozaki H, Asano T, Miyata T, Kawaguchi Y, Yasuda Y, Kobayashi T, Sugiyama M, Onoue T, Hagiwara D, Iwama S, Oyadomari S, Arima H

Peptides 173 巻頁： 171151 - 171151 2024年3月

Effects of Digitization of Self-Monitoring of Blood Glucose Records Using a Mobile App and the Cloud System on Outpatient Management of Diabetes: Single-Armed Prospective Study.

Handa T, Onoue T, Kobayashi T, Maeda R, Mizutani K, Yamagami A, Kinoshita T, Yasuda Y, Iwama S, Miyata T, Sugiyama M, Takagi H, Hagiwara D, Suga H, Banno R, Azuma Y, Kasai T, Yoshioka S, Kuwatsuka Y, Arima H

JMIR diabetes 9 巻頁： e48019 2024年1月

Improved glycemic control after the use of flash glucose monitoring accompanied by improved treatment satisfaction in patients with non-insulin-treated type 2 diabetes: A post-hoc analysis of a randomized controlled trial 査読有り国際誌

Hayase, A; Onoue, T; Kobayashi, T; Wada, E; Handa, T; Kinoshita, T; Yamagami, A; Yasuda, Y; Iwama, S; Kawaguchi, Y; Miyata, T; Sugiyama, M; Takagi, H; Hagiwara, D; Suga, H; Banno, R; Kuwatsuka, Y; Ando, M; Goto, M; Arima, H

PRIMARY CARE DIABETES 17 巻 ( 6 ) 頁： 575 - 580 2023年12月

Touch imprint cytology is useful for the intraoperative pathological diagnosis of PitNETs' surgical margins 査読有り

Tanabe, N; Inoshita, N; Ishida, A; Kato, M; Yoshimoto, H; Shiramizu, H; Suga, H; Tateno, T; Ohashi, K; Yamada, S

BRAIN TUMOR PATHOLOGY 40 巻 ( 4 ) 頁： 215 - 221 2023年10月

Generation and purification of ACTH-secreting hPSC-derived pituitary cells for effective transplantation 査読有り国際誌

Taga, S; Suga, H; Nakano, T; Kuwahara, A; Inoshita, N; Kodani, Y; Nagasaki, H; Sato, Y; Tsumura, Y; Sakakibara, M; Soen, M; Miwata, T; Ozaki, H; Kano, M; Watari, K; Ikeda, A; Yamanaka, M; Takahashi, Y; Kitamoto, S; Kawaguchi, Y; Miyata, T; Kobayashi, T; Sugiyama, M; Onoue, T; Yasuda, Y; Hagiwara, D; Iwama, S; Tomigahara, Y; Kimura, T; Arima, H

STEM CELL REPORTS 18 巻 ( 8 ) 頁： 1657 - 1671 2023年8月

Functional calcium-responsive parathyroid glands generated using single-step blastocyst complementation. 査読有り国際誌

Kano M, Mizuno N, Sato H, Kimura T, Hirochika R, Iwasaki Y, Inoshita N, Nagano H, Kasai M, Yamamoto H, Yamaguchi T, Suga H, Masaki H, Mizutani E, Nakauchi H

Proceedings of the National Academy of Sciences of the United States of America 120 巻 ( 28 ) 頁： e2216564120 2023年7月

Anti-tumor effects of anti-programmed cell death-1 antibody treatment are attenuated in streptozotocin-induced diabetic mice 査読有り国際誌

Ito, M; Iwama, S; Sugiyama, D; Yasuda, Y; Okuji, T; Kobayashi, T; Zhou, X; Yamagami, A; Onoue, T; Miyata, T; Sugiyama, M; Hagiwara, D; Suga, H; Banno, R; Nishikawa, H; Arima, H

SCIENTIFIC REPORTS 13 巻 ( 1 ) 頁： 5939 - 5939 2023年4月

Generation of hypothalamic neural stem cell-like cells in vitro from human pluripotent stem cells 査読有り国際誌

Miwata, T; Suga, H; Kawaguchi, Y; Sakakibara, M; Kano, M; Taga, S; Soen, M; Ozaki, H; Asano, T; Sasaki, H; Miyata, T; Yasuda, Y; Kobayashi, T; Sugiyama, M; Onoue, T; Takagi, H; Hagiwara, D; Iwama, S; Arima, H

STEM CELL REPORTS 18 巻 ( 4 ) 頁： 869 - 883 2023年4月

Mineralocorticoids induce polyuria by reducing apical aquaporin-2 expression of the kidney in partial vasopressin deficiency.

Kurimoto J, Takagi H, Miyata T, Kawaguchi Y, Hodai Y, Tsumura T, Hagiwara D, Kobayashi T, Yasuda Y, Sugiyama M, Onoue T, Iwama S, Suga H, Banno R, Katsuki T, Ando F, Uchida S, Arima H

Endocrine journal 70 巻 ( 3 ) 頁： 295 - 304 2023年3月

Subcutaneous transplantation of human embryonic stem cells-derived pituitary organoids 査読有り

Sasaki, H; Suga, H; Takeuchi, K; Nagata, Y; Harada, H; Kondo, T; Ito, E; Maeda, S; Sakakibara, M; Soen, M; Miwata, T; Asano, T; Ozaki, H; Taga, S; Kuwahara, A; Nakano, T; Arima, H; Saito, R

FRONTIERS IN ENDOCRINOLOGY 14 巻頁： 1130465 - - 2023年3月

Resting energy expenditure depends on energy intake during weight loss in people with obesity: a retrospective cohort study 査読有り国際誌

Handa, T; Onoue, T; Kobayashi, T; Wada, E; Hayase, A; Kinoshita, T; Yamagami, A; Yasuda, Y; Iwama, S; Kawaguchi, Y; Miyata, T; Sugiyama, M; Takagi, H; Hagiwara, D; Suga, H; Banno, R; Goto, M; Arima, H

ARCHIVES OF ENDOCRINOLOGY METABOLISM 67 巻 ( 2 ) 頁： 233 - 241 2023年3月

Recipe for pituitary organoids 国際誌

Kano, M; Sasaki, H; Miwata, T; Suga, H

FRONTIERS IN ENDOCRINOLOGY 13 巻頁： 1025825 - 1025825 2023年1月

Knockdown of endoplasmic reticulum chaperone BiP leads to the death of parvocellular AVP/CRH neurons in mice

Kawaguchi, Y; Hagiwara, D; Tsumura, T; Miyata, T; Kobayashi, T; Sugiyama, M; Onoue, T; Yasuda, Y; Iwama, S; Suga, H; Banno, R; Grinevich, V; Arima, H

JOURNAL OF NEUROENDOCRINOLOGY 35 巻 ( 1 ) 頁： e13223 2023年1月

Synergistic effect of amino acid substitutions in CYP51B for prochloraz resistance in Fusarium fujikuroi

Li, FJ; Ebihara, A; Sakahara, Y; Matsumoto, S; Ueno, R; Bao, WX; Kimura, M; Fuji, S; Shimizu, M; Kageyama, K; Suga, H

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY 189 巻頁： 105291 2023年1月

Mineralocorticoids induce polyuria by reducing apical aquaporin-2 expression of the kidney in partial vasopressin deficiency

Kurimoto Junki, Takagi Hiroshi, Miyata Takashi, Kawaguchi Yohei, Hodai Yuichi, Tsumura Tetsuro, Hagiwara Daisuke, Kobayashi Tomoko, Yasuda Yoshinori, Sugiyama Mariko, Onoue Takeshi, Iwama Shintaro, Suga Hidetaka, Banno Ryoichi, Katsuki Takeshi, Ando Fumiaki, Uchida Shinichi, Arima Hiroshi

ENDOCRINE JOURNAL 70 巻 ( 3 ) 頁： 295 - 304 2023年

Long-range axonal projections of transplanted mouse embryonic stem cell-derived hypothalamic neurons into adult mouse brain 国際誌

Kawata, M; Kodani, Y; Ohkuma, M; Miyachi, EI; Kaneko, YS; Nakashima, A; Suga, H; Kameyama, T; Saito, K; Nagasaki, H

PLOS ONE 17 巻 ( 11 ) 頁： e0276694 2022年11月

Differentiation of human induced pluripotent stem cells into hypothalamic vasopressin neurons with minimal exogenous signals and partial conversion to the naive state 査読有り国際誌

Ozaki, H; Suga, H; Sakakibara, M; Soen, M; Miyake, N; Miwata, T; Taga, S; Nagai, T; Kano, M; Mitsumoto, K; Miyata, T; Kobayashi, T; Sugiyama, M; Onoue, T; Takagi, H; Hagiwara, D; Iwama, S; Banno, R; Iguchi, G; Takahashi, Y; Muguruma, K; Inoue, H; Arima, H

SCIENTIFIC REPORTS 12 巻 ( 1 ) 頁： 17381 - - 2022年10月

Elevated TSH Level, TgAb, and Prior Use of Ramucirumab or TKIs as Risk Factors for Thyroid Dysfunction in PD-L1 Blockade 査読有り国際誌

Kobayashi, T; Iwama, S; Yamagami, A; Yasuda, Y; Okuji, T; Ito, M; Zhou, X; Ando, M; Onoue, T; Miyata, T; Sugiyama, M; Hagiwara, D; Suga, H; Banno, R; Hase, T; Morise, M; Ito, T; Kikumori, T; Inoue, M; Ando, Y; Masuda, N; Kawashima, H; Hashimoto, N; Arima, H

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 107 巻 ( 10 ) 頁： E4115 - E4123 2022年9月

Protein Tyrosine Phosphatase 1B Deficiency Improves Glucose Homeostasis in Type 1 Diabetes Treated With Leptin 査読有り国際誌

Ito, Y; Sun, R; Yagimuma, H; Taki, K; Mizoguchi, A; Kobayashi, T; Sugiyama, M; Onoue, T; Tsunekawa, T; Takagi, H; Hagiwara, D; Iwama, S; Suga, H; Konishi, H; Kiyama, H; Arima, H; Banno, R

DIABETES 71 巻 ( 9 ) 頁： 1902 - 1914 2022年9月

Inflammation in VTA Caused by HFD Induces Activation of Dopaminergic Neurons Accompanied by Binge-like Eating 国際誌

Sun, RN; Sugiyama, M; Wang, SX; Kuno, M; Sasaki, T; Hirose, T; Miyata, T; Kobayashi, T; Tsunekawa, T; Onoue, T; Yasuda, Y; Takagi, H; Hagiwara, D; Iwama, S; Suga, H; Arima, H

NUTRIENTS 14 巻 ( 18 ) 頁： 3835 - 3835 2022年9月

Disease Modeling of Pituitary Adenoma Using Human Pluripotent Stem Cells 査読有り

Matsumoto, R; Suga, H; Arima, H; Yamamoto, T

CANCERS 14 巻 ( 15 ) 頁： 3660 2022年8月

EpCAM Is a Surface Marker for Enriching Anterior Pituitary Cells From Human Hypothalamic-Pituitary Organoids 査読有り

Kodani, Y; Kawata, M; Suga, H; Kasai, T; Ozone, C; Sakakibara, M; Kuwahara, A; Taga, S; Arima, H; Kameyama, T; Saito, K; Nakashima, A; Nagasaki, H

FRONTIERS IN ENDOCRINOLOGY 13 巻頁： 941166 2022年7月

Increased Risk of Thyroid Dysfunction by PD-1 and CTLA-4 Blockade in Patients Without Thyroid Autoantibodies at Baseline 国際誌

Iwama, S; Kobayashi, T; Yasuda, Y; Okuji, T; Ito, M; Ando, M; Zhou, X; Yamagami, A; Onoue, T; Kawaguchi, Y; Miyata, T; Sugiyama, M; Takagi, H; Hagiwara, D; Suga, H; Banno, R; Hase, T; Morise, M; Wakahara, K; Yokota, K; Kato, M; Nishio, N; Tanaka, C; Miyata, K; Ogura, A; Ito, T; Sawada, T; Shimokata, T; Niimi, K; Ohka, F; Ishigami, M; Gotoh, M; Hashimoto, N; Saito, R; Kiyoi, H; Kajiyama, H; Ando, Y; Hibi, H; Sone, M; Akiyama, M; Kodera, Y; Arima, H

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM 107 巻 ( 4 ) 頁： E1620 - E1630 2022年3月

Functional Lactotrophs in Induced Adenohypophysis Differentiated From Human iPS Cells 査読有り国際誌

Miyake, N; Nagai, T; Suga, H; Osuka, S; Kasai, T; Sakakibara, M; Soen, M; Ozaki, H; Miwata, T; Asano, T; Kano, M; Muraoka, A; Nakanishi, N; Nakamura, T; Goto, M; Yasuda, Y; Kawaguchi, Y; Miyata, T; Kobayashi, T; Sugiyama, M; Onoue, T; Hagiwara, D; Iwama, S; Iwase, A; Inoshita, N; Arima, H; Kajiyama, H

ENDOCRINOLOGY 163 巻 ( 3 ) 頁： bqac004 - - 2022年3月

Characterization of Hypothalamic MCH Neuron Development in a 3D Differentiation System of Mouse Embryonic Stem Cells 査読有り国際誌

Kodani, Y; Kawata, M; Suga, H; Kaneko, YS; Nakashima, A; Kameyama, T; Saito, K; Nagasaki, H

ENEURO 9 巻 ( 2 ) 頁： ENEURO.0442 - 21.2022 2022年3月

ヒト疾患特異的人工多能性幹細胞(iPS細胞)からのバソプレシン(AVP)神経の分化誘導による家族性中枢性尿崩症(FNDI)のin vitroヒト疾患モデル

尾崎創, 須賀英隆, 三輪田勤, 井口元三, 高橋裕, 有馬寛

日本内分泌学会雑誌 97 巻 ( 5 ) 頁： 1243 - 1243 2022年3月

Predicting non-insulin-dependent state in patients with slowly progressive insulin-dependent (type 1) diabetes mellitus or latent autoimmune diabetes in adults. Reply to Sugiyama K and Saisho Y [letter]

Wada, E; Onoue, T; Kinoshita, T; Hayase, A; Handa, T; Ito, M; Furukawa, M; Okuji, T; Kobayashi, T; Iwama, S; Sugiyama, M; Takagi, H; Hagiwara, D; Suga, H; Banno, R; Goto, M; Arima, H

DIABETOLOGIA 65 巻 ( 1 ) 頁： 252 - 253 2022年1月

Adult-onset autoimmune diabetes identified by glutamic acid decarboxylase autoantibodies: a retrospective cohort study

Wada, E; Onoue, T; Kinoshita, T; Hayase, A; Handa, T; Ito, M; Furukawa, M; Okuji, T; Kobayashi, T; Iwama, S; Sugiyama, M; Takagi, H; Hagiwara, D; Suga, H; Banno, R; Goto, M; Arima, H

DIABETOLOGIA 64 巻 ( 10 ) 頁： 2183 - 2192 2021年10月

GABAB receptor signaling in the caudate putamen is involved in binge-like consumption during a high fat diet in mice 国際誌

Sun, RN; Tsunekawa, T; Hirose, T; Yaginuma, H; Taki, K; Mizoguchi, A; Miyata, T; Kobayashi, T; Sugiyama, M; Onoue, T; Takagi, H; Hagiwara, D; Ito, Y; Iwama, S; Suga, H; Banno, R; Bettler, B; Arima, H

SCIENTIFIC REPORTS 11 巻 ( 1 ) 頁： 19296 - 19296 2021年9月

Deficiency of WFS1 leads to the impairment of AVP secretion under dehydration in male mice 査読有り国際誌

Kurimoto, J; Takagi, H; Miyata, T; Hodai, Y; Kawaguchi, Y; Hagiwara, D; Suga, H; Kobayashi, T; Sugiyama, M; Onoue, T; Ito, Y; Iwama, S; Banno, R; Tanabe, K; Tanizawa, Y; Arima, H

PITUITARY 24 巻 ( 4 ) 頁： 582 - 588 2021年8月

Adult-onset autoimmune diabetes identified by glutamic acid decarboxylase autoantibodies: a retrospective cohort study. 査読有り

Wada E, Onoue T, Kinoshita T, Hayase A, Handa T, Ito M, Furukawa M, Okuji T, Kobayashi T, Iwama S, Sugiyama M, Takagi H, Hagiwara D, Suga H, Banno R, Goto M, Arima H

DIABETOLOGIA 64 巻 ( 10 ) 頁： 2183 - 2192 2021年7月

Glucocorticoid receptor signaling in ventral tegmental area neurons increases the rewarding value of a high-fat diet in mice 招待有り

Mizoguchi Akira, Banno Ryoichi, Sun Runan, Yaginuma Hiroshi, Taki Keigo, Kobayashi Tomoko, Sugiyama Mariko, Tsunekawa Taku, Onoue Takeshi, Takagi Hiroshi, Hagiwara Daisuke, Ito Yoshihiro, Iwama Shintaro, Suga Hidetaka, Nagai Taku, Yamada Kiyofumi, Arima Hiroshi

SCIENTIFIC REPORTS 11 巻 ( 1 ) 頁： 12873 2021年6月

Glucocorticoid receptor signaling in ventral tegmental area neurons increases the rewarding value of a high-fat diet in mice. 査読有り

Mizoguchi, A, Banno, R, Sun, R, Yaginuma, H, Taki, K, Kobayashi, T, Sugiyama, M, Tsunekawa, T, Onoue, T, Takagi, H, Hagiwara, D, Ito, Y, Iwama, S, Suga, H, Nagai, T, Yamada, K, Arima, H

Scientific Reports 11 巻頁： 12873 - - 2021年6月

A new primate model of hypophyseal dysfunction 査読有り国際誌

Kawabata, T; Suga, H; Takeuchi, K; Nagata, Y; Sakakibara, M; Ushida, K; Ozone, C; Enomoto, A; Kawamoto, I; Itagaki, I; Tsuchiya, H; Arima, H; Wakabayashi, T

SCIENTIFIC REPORTS 11 巻 ( 1 ) 頁： 10729 - 10729 2021年5月

CD4(+) T cells are essential for the development of destructive thyroiditis induced by anti-PD-1 antibody in thyroglobulin-immunized mice

Yasuda Yoshinori, Iwama Shintaro, Sugiyama Daisuke, Okuji Takayuki, Kobayashi Tomoko, Ito Masaaki, Okada Norio, Enomoto Atsushi, Ito Sachiko, Yan Yue, Sugiyama Mariko, Onoue Takeshi, Tsunekawa Taku, Ito Yoshihiro, Takagi Hiroshi, Hagiwara Daisuke, Goto Motomitsu, Suga Hidetaka, Banno Ryoichi, Takahashi Masahide, Nishikawa Hiroyoshi, Arima Hiroshi

SCIENCE TRANSLATIONAL MEDICINE 13 巻 ( 593 ) 2021年5月

High-fat Feeding Causes Inflammation and Insulin Resistance in the Ventral Tegmental Area in Mice 査読有り国際誌

Mizoguchi, A; Banno, R; Sun, RN; Yaginuma, H; Taki, K; Kobayashi, T; Sugiyama, M; Tsunekawa, T; Onoue, T; Takagi, H; Hagiwara, D; Ito, Y; Iwama, S; Suga, H; Arima, H

NEUROSCIENCE 461 巻頁： 72 - 79 2021年5月

Arginine vasopressin-Venus reporter mice as a tool for studying magnocellular arginine vasopressin neurons 査読有り国際誌

Hagiwara, D; Tochiya, M; Azuma, Y; Tsumura, T; Hodai, Y; Kawaguchi, Y; Miyata, T; Kobayashi, T; Sugiyama, M; Onoue, T; Takagi, H; Ito, Y; Iwama, S; Suga, H; Banno, R; Arima, H

PEPTIDES 139 巻頁： 170517 - 170517 2021年5月

Anti-pituitary antibodies and susceptible human leukocyte antigen alleles as predictive biomarkers for pituitary dysfunction induced by immune checkpoint inhibitors 査読有り国際誌

Kobayashi, T; Iwama, S; Sugiyama, D; Yasuda, Y; Okuji, T; Ito, M; Ito, S; Sugiyama, M; Onoue, T; Takagi, H; Hagiwara, D; Ito, Y; Suga, H; Banno, R; Nishikawa, H; Arima, H

JOURNAL FOR IMMUNOTHERAPY OF CANCER 9 巻 ( 5 ) 頁： e002493 - e002493 2021年5月

Dietary sodium chloride attenuates increased β-cell mass to cause glucose intolerance in mice under a high-fat diet 査読有り国際誌

Taki, K; Takagi, H; Hirose, T; Sun, RN; Yaginuma, H; Mizoguchi, A; Kobayashi, T; Sugiyama, M; Tsunekawa, T; Onoue, T; Hagiwara, D; Ito, Y; Iwama, S; Suga, H; Banno, R; Sakano, D; Kume, S; Arima, H

PLOS ONE 16 巻 ( 3 ) 頁： e0248065 2021年3月

Induction of Functional Hypothalamus and Pituitary Tissues From Pluripotent Stem Cells for Regenerative Medicine 査読有り国際誌

Kano, M; Suga, H; Arima, H

JOURNAL OF THE ENDOCRINE SOCIETY 5 巻 ( 3 ) 頁： bvaa188 2021年3月

Hypothalamic-pituitary organoid generation through the recapitulation of organogenesis 査読有り

Ozaki, H; Suga, H; Arima, H

DEVELOPMENT GROWTH & DIFFERENTIATION 63 巻 ( 2 ) 頁： 154 - 165 2021年2月

Peripheral combination treatment of leptin and an SGLT2 inhibitor improved glucose metabolism in insulin-dependent diabetes mellitus mice

Yaginuma, H; Banno, R; Sun, R; Taki, K; Mizoguchi, A; Kobayashi, T; Sugiyama, M; Tsunekawa, T; Onoue, T; Takagi, H; Hagiwara, D; Ito, Y; Iwama, S; Suga, H; Arima, H

JOURNAL OF PHARMACOLOGICAL SCIENCES 147 巻 ( 4 ) 頁： 340 - 347 2021年

Endoplasmic reticulum chaperone BiP/GRP78 knockdown leads to autophagy and cell death of arginine vasopressin neurons in mice 査読有り国際誌

Kawaguchi, Y; Hagiwara, D; Miyata, T; Hodai, Y; Kurimoto, J; Takagi, H; Suga, H; Kobayashi, T; Sugiyama, M; Onoue, T; Ito, Y; Iwama, S; Banno, R; Grinevich, V; Arima, H

SCIENTIFIC REPORTS 10 巻 ( 1 ) 頁： 19730 - 19730 2020年11月

Degradation of Mutant Protein Aggregates within the Endoplasmic Reticulum of Vasopressin Neurons 国際誌

Miyata, T; Hagiwara, D; Hodai, Y; Miwata, T; Kawaguchi, Y; Kurimoto, J; Ozaki, H; Mitsumoto, K; Takagi, H; Suga, H; Kobayashi, T; Sugiyama, M; Onoue, T; Ito, Y; Iwama, S; Banno, R; Matsumoto, M; Kawakami, N; Ohno, N; Sakamoto, H; Arima, H

ISCIENCE 23 巻 ( 10 ) 頁： 101648 - 101648 2020年10月

Generation of four induced pluripotent stem cell lines (FHUi003-A, FHUi003-B, FHUi004-A and FHUi004-B) from two affected individuals of a familial neurohypophyseal diabetes insipidus family 査読有り国際誌

Yoshida, S; Okura, H; Suga, H; Soen, M; Kawaguchi, Y; Kurimoto, J; Miyata, T; Takagi, H; Arima, H; Fujikawa, T; Otsuka, F; Matsuyama, A

STEM CELL RESEARCH 48 巻頁： 101960 - 101960 2020年10月

Generation of three induced pluripotent stem cell (iPSC) lines from a multiple endocrine neoplasia type 1 (MEN1) patient and three iPSC lines from an unaffected relative of the patient 査読有り国際誌

Yoshida, S; Okura, H; Suga, H; Nishitomi, T; Sakurai, A; Arima, H; Matsuyama, A

STEM CELL RESEARCH 46 巻頁： 101846 - 101846 2020年7月

Hypothalamic glial cells isolated by MACS reveal that microglia and astrocytes induce hypothalamic inflammation via different processes under high-fat diet conditions 査読有り国際誌

Sugiyama, M; Banno, R; Yaginuma, H; Taki, K; Mizoguchi, A; Tsunekawa, T; Onoue, T; Takagi, H; Ito, Y; Iwama, S; Goto, M; Suga, H; Komine, O; Yamanaka, K; Arima, H

NEUROCHEMISTRY INTERNATIONAL 136 巻頁： 104733 - 104733 2020年6月

Anti-thyroid antibodies and thyroid echo pattern at baseline as risk factors for thyroid dysfunction induced by anti-programmed cell death-1 antibodies: a prospective study 査読有り国際誌

Okada, N; Iwama, S; Okuji, T; Kobayashi, T; Yasuda, Y; Wada, E; Onoue, T; Goto, M; Sugiyama, M; Tsunekawa, T; Takagi, H; Hagiwara, D; Ito, Y; Suga, H; Banno, R; Hase, T; Morise, M; Kanda, M; Yokota, K; Hashimoto, N; Ando, M; Fujimoto, Y; Nagino, M; Kodera, Y; Fujishiro, M; Hibi, H; Sone, M; Kiyoi, H; Gotoh, M; Ando, Y; Akiyama, M; Hasegawa, Y; Arima, H

BRITISH JOURNAL OF CANCER 122 巻 ( 6 ) 頁： 771 - 777 2020年3月

Congenital pituitary hypoplasia model demonstrates hypothalamic OTX2 regulation of pituitary progenitor cells 査読有り国際誌

Matsumoto, R; Suga, H; Aoi, T; Bando, H; Fukuoka, H; Iguchi, G; Narumi, S; Hasegawa, T; Muguruma, K; Ogawa, W; Takahashi, Y

JOURNAL OF CLINICAL INVESTIGATION 130 巻 ( 2 ) 頁： 641 - 654 2020年2月

Dipeptidyl peptidase-4 inhibitor anagliptin reduces fasting apolipoprotein B-48 levels in patients with type 2 diabetes: A randomized controlled 査読有り国際誌

Onoue, T; Goto, M; Wada, E; Furukawa, M; Okuji, T; Okada, N; Kobayashi, T; Iwama, S; Sugiyama, M; Tsunekawa, T; Takagi, H; Hagiwara, D; Ito, Y; Morishita, Y; Seino, Y; Suga, H; Banno, R; Hamada, Y; Ando, M; Yamamori, E; Arima, H

PLOS ONE 15 巻 ( 1 ) 頁： e0228004 2020年1月

Hypothalamic Contribution to Pituitary Functions Is Recapitulated In Vitro Using 3D-Cultured Human iPS Cells 査読有り国際誌

Kasai, T; Suga, H; Sakakibara, M; Ozone, C; Matsumoto, R; Kano, M; Mitsumoto, K; Ogawa, K; Kodani, Y; Nagasaki, H; Inoshita, N; Sugiyama, M; Onoue, T; Tsunekawa, T; Ito, Y; Takagi, H; Hagiwara, D; Iwama, S; Goto, M; Banno, R; Takahashi, J; Arima, H

CELL REPORTS 30 巻 ( 1 ) 頁： 18 - + 2020年1月

Flash glucose monitoring helps achieve better glycemic control than conventional self-monitoring of blood glucose in non-insulin-treated type 2 diabetes: a randomized controlled trial 査読有り国際誌

Wada, E; Onoue, T; Kobayashi, T; Handa, T; Hayase, A; Ito, M; Furukawa, M; Okuji, T; Okada, N; Iwama, S; Sugiyama, M; Tsunekawa, T; Takagi, H; Hagiwara, D; Ito, Y; Suga, H; Banno, R; Kuwatsuka, Y; Ando, M; Goto, M; Arima, H

BMJ OPEN DIABETES RESEARCH & CARE 8 巻 ( 1 ) 2020年1月

Diagnosis of central diabetes insipidus using a vasopressin radioimmunoassay during hypertonic saline infusion 査読有り国際誌

Takagi, H; Hagiwara, D; Handa, T; Sugiyama, M; Onoue, T; Tsunekawa, T; Ito, Y; Iwama, S; Goto, M; Suga, H; Banno, R; Takahashi, K; Matsui, S; Arima, H

ENDOCRINE JOURNAL 67 巻 ( 3 ) 頁： 267 - 274 2020年

Pituitary dysfunction induced by immune checkpoint inhibitors is associated with better overall survival in both malignant melanoma and non-small cell lung carcinoma: a prospective study 国際誌

Kobayashi, T; Iwama, S; Yasuda, Y; Okada, N; Okuji, T; Ito, M; Onoue, T; Goto, M; Sugiyama, M; Tsunekawa, T; Takagi, H; Hagiwara, D; Ito, Y; Suga, H; Banno, R; Yokota, K; Hase, T; Morise, M; Hashimoto, N; Ando, M; Fujimoto, Y; Hibi, H; Sone, M; Ando, Y; Akiyama, M; Hasegawa, Y; Arima, H

JOURNAL FOR IMMUNOTHERAPY OF CANCER 8 巻 ( 2 ) 2020年

GABAB Receptor Signaling in the Mesolimbic System Suppresses Binge-like Consumption of a High-Fat Diet 国際誌

Tsunekawa, T; Banno, R; Yaginuma, H; Taki, K; Mizoguchi, A; Sugiyama, M; Onoue, T; Takagi, H; Hagiwara, D; Ito, Y; Iwama, S; Goto, M; Suga, H; Bettler, B; Arima, H

ISCIENCE 20 巻頁： 337 - + 2019年10月

Improved methods for the differentiation of hypothalamic vasopressin neurons using mouse induced pluripotent stem cells 査読有り国際誌

Mitsumoto, K; Suga, H; Sakakibara, M; Soen, M; Yamada, T; Ozaki, H; Nagai, T; Kano, M; Kasai, T; Ozone, C; Ogawa, K; Sugiyama, M; Onoue, T; Tsunekawa, T; Takagi, H; Hagiwara, D; Ito, Y; Iwama, S; Goto, M; Banno, R; Arima, H

STEM CELL RESEARCH 40 巻頁： 101572 - - 2019年10月

Tanycyte-Like Cells Derived From Mouse Embryonic Stem Culture Show Hypothalamic Neural Stem/Progenitor Cell Functions 査読有り国際誌

Kano, M; Suga, H; Ishihara, T; Sakakibara, M; Soen, M; Yamada, T; Ozaki, H; Mitsumoto, K; Kasai, T; Sugiyama, M; Onoue, T; Tsunekawa, T; Takagi, H; Hagiwara, D; Ito, Y; Iwama, S; Goto, M; Banno, R; Arima, H

ENDOCRINOLOGY 160 巻 ( 7 ) 頁： 1701 - 1718 2019年7月

Application of pluripotent stem cells for treatment of human neuroendocrine disorders 査読有り

Suga, H

CELL AND TISSUE RESEARCH 375 巻 ( 1 ) 頁： 267 - 278 2019年1月

Chemical chaperone 4-phenylbutylate reduces mutant protein accumulation in the endoplasmic reticulum of arginine vasopressin neurons in a mouse model for familial neurohypophysial diabetes insipidus 査読有り

Tochiya, M; Hagiwara, D; Azuma, Y; Miyata, T; Morishita, Y; Suga, H; Onoue, T; Tsunekawa, T; Takagi, H; Ito, Y; Iwama, S; Goto, M; Banno, R; Arima, H

NEUROSCIENCE LETTERS 682 巻頁： 50 - 55 2018年8月

＜Editors' Choice＞ Effects of exosomes derived from the induced pluripotent stem cells on skin wound healing. 査読有り

Kobayashi H, Ebisawa K, Kambe M, Kasai T, Suga H, Nakamura K, Narita Y, Ogata A, Kamei Y

Nagoya journal of medical science 80 巻 ( 2 ) 頁： 141 - 153 2018年5月

Effects of exosomes derived from the induced pluripotent stem cells on skin wound healing

Kobayashi Hitoshi, Ebisawa Katsumi, Kambe Miki, Kasai Takatoshi, Suga Hidetaka, Nakamura Kae, Narita Yuji, Ogata Aika, Kamei Yuzuru

NAGOYA JOURNAL OF MEDICAL SCIENCE 80 巻 ( 2 ) 頁： 141 - 153 2018年5月

Critical role of rabphilin-3A in the pathophysiology of experimental lymphocytic neurohypophysitis 査読有り

Yasuda, Y; Iwama, S; Kiyota, A; Izumida, H; Nakashima, K; Iwata, N; Ito, Y; Morishita, Y; Goto, M; Suga, H; Banno, R; Enomoto, A; Takahashi, M; Arima, H; Sugimura, Y

JOURNAL OF PATHOLOGY 244 巻 ( 4 ) 頁： 469 - 478 2018年4月

Functional Pituitary Tissue Generation from Human Embryonic Stem Cells. 査読有り国際誌

Kano M, Suga H, Kasai T, Ozone C, Arima H

Current protocols in neuroscience 83 巻 ( 1 ) 頁： e48 2018年4月

Patients With Antithyroid Antibodies Are Prone To Develop Destructive Thyroiditis by Nivolumab: A Prospective Study. 査読有り国際誌

Kobayashi T, Iwama S, Yasuda Y, Okada N, Tsunekawa T, Onoue T, Takagi H, Hagiwara D, Ito Y, Morishita Y, Goto M, Suga H, Banno R, Yokota K, Hase T, Morise M, Hashimoto N, Ando M, Kiyoi H, Gotoh M, Ando Y, Akiyama M, Hasegawa Y, Arima H

Journal of the Endocrine Society 2 巻 ( 3 ) 頁： 241 - 251 2018年3月

Vasopressin-secreting neurons derived from human embryonic stem cells through specific induction of dorsal hypothalamic progenitors 査読有り

Ogawa, K; Suga, H; Ozone, C; Sakakibara, M; Yamada, T; Kano, M; Mitsumoto, K; Kasai, T; Kodani, Y; Nagasaki, H; Yamamoto, N; Hagiwara, D; Goto, M; Banno, R; Sugimura, Y; Arima, H

SCIENTIFIC REPORTS 8 巻 ( 1 ) 頁： 3615 2018年2月

Sequestosome 1 (SQSTMI/p62) maintains protein folding capacity under endoplasmic reticulum stress in mouse hypothalamic organotypic culture 査読有り

Tominaga, T; Goto, M; Onoue, T; Mizoguchi, A; Sugiyama, M; Tsunekawa, T; Hagiwara, D; Morishita, Y; Ito, Y; Iwama, S; Suga, H; Banno, R; Arima, H

NEUROSCIENCE LETTERS 656 巻頁： 103 - 107 2017年8月

PTP1B deficiency improves hypothalamic insulin sensitivity resulting in the attenuation of AgRP mRNA expression under high-fat diet conditions 査読有り

Sugiyama, M; Banno, R; Mizoguchi, A; Tominaga, T; Tsunekawa, T; Onoue, T; Hagiwara, D; Ito, Y; Morishita, Y; Iwama, S; Goto, M; Suga, H; Arima, H

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 488 巻 ( 1 ) 頁： 116 - 121 2017年6月

Anti-pituitary antibodies against corticotrophs in IgG4-related hypophysitis 査読有り

Iwata, N; Iwama, S; Sugimura, Y; Yasuda, Y; Nakashima, K; Takeuchi, S; Hagiwara, D; Ito, Y; Suga, H; Goto, M; Banno, R; Caturegli, P; Koike, T; Oshida, Y; Arima, H

PITUITARY 20 巻 ( 3 ) 頁： 301 - 310 2017年6月

Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia 査読有り国際誌

Tsunekawa, T; Banno, R; Mizoguchi, A; Sugiyama, M; Tominaga, T; Onoue, T; Hagiwara, D; Ito, Y; Iwama, S; Goto, M; Suga, H; Sugimura, Y; Arima, H

EBIOMEDICINE 16 巻頁： 172 - 183 2017年2月

Functional Pituitary Tissue Formation 査読有り国際誌

Ozone, C; Suga, H

ORGAN REGENERATION: 3D STEM CELL CULTURE & MANIPULATION 1597 巻頁： 57 - 65 2017年

Making pituitary hormone-producing cells in a dish.

Hidetaka Suga

Endocrine Journal 63 巻 ( 8 ) 頁： 669-680 2016年8月

Recapitulating Hypothalamus and Pituitary Development Using Embryonic Stem/Induced Pluripotent Stem Cells.

Hidetaka Suga

Research and Perspectives in Endocrine Interactions (Stem Cells in Neuroendocrinology) 頁： 35-50 2016年8月

Differentiation of pluripotent stem cells into hypothalamic and pituitary cells. 査読有り

Hidetaka Suga

Neuroendocrinology 101 巻頁： 18-24 2015年4月

劇症１型糖尿病を合併した薬剤性過敏症症候群の１例

落合啓史、岡嵜裕子、尾方秀忠、須賀英隆、恒川新、大磯ユタカ

日本内科学会雑誌 103 巻 ( 5 ) 頁： 1183-1186 2014年5月

Arginine vasopressin neuronal loss results from autophagy-associated cell death in a mouse model for familial neurohypophysial diabetes insipidus.

Hagiwara D, Arima H, Morishita Y, Wenjun L, Azuma Y, Ito Y, Suga H, Goto M, Banno R, Sugimura Y, Shiota A, Asai N, Takahashi M, Oiso Y.

Cell Death Dis. 5 巻頁： e1148 2014年

Mitogen-activated protein kinase phosphatase 1 negatively regulates MAPK signaling in mouse hypothalamus.

Adachi K, Goto M, Onoue T, Tsunekawa T, Shibata M, Hagimoto S, Ito Y, Banno R, Suga H, Sugimura Y, Oiso Y, Arima H.

Neurosci Lett. 569 巻頁： 49-54 2014年

Minocycline prevents osmotic demyelination associated with aquaresis.

Takagi H, Sugimura Y, Suzuki H, Iwama S, Izumida H, Fujisawa H, Ogawa K, Nakashima K, Ochiai H, Takeuchi S, Kiyota A, Suga H, Goto M, Banno R, Arima H, Oiso Y.

Kidney Int. 86 巻 ( 5 ) 頁： 954-964 2014年

Activating transcription factor 6α is required for the vasopressin neuron system to maintain water balance under dehydration in male mice.

Azuma Y, Hagiwara D, Lu W, Morishita Y, Suga H, Goto M, Banno R, Sugimura Y, Oyadomari S, Mori K, Shiota A, Asai N, Takahashi M, Oiso Y, Arima H.

Endocrinology 155 巻 ( 12 ) 頁： 4905-4914 2014年

GABA type B receptor signaling in proopiomelanocortin neurons protects against obesity, insulin resistance, and hypothalamic inflammation in male mice on a high-fat diet.

Ito Y, Banno R, Shibata M, Adachi K, Hagimoto S, Hagiwara D, Ozawa Y, Goto M, Suga H, Sugimura Y, Bettler B, Oiso Y. Arima H.

J Neurosci 33 巻 ( 43 ) 頁： 17166-171673 2013年

Expression of neuropeptide Y and agouti-related protein mRNA stimulated by glucocorticoids is attenuated via NF-κB p65 under ER stress in mouse hypothalamic cultures.

Hagimoto S, Arima H, Adachi K, Ito Y, Suga H, Sugimura Y, Goto M, Banno R, Oiso Y.

Neurosci Lett. 553 巻頁： 165-169 2013年

In vitro organogenesis in three dimensions: self-organising stem cells.

Sasai Y, Eiraku M, Suga H.

Development. 139 巻 ( 22 ) 頁： 4111-4121 2012年

Self-formation of functional adenohypophysis in three-dimensional culture.

Suga H, Kadoshima T, Minaguchi M, Ohgushi M, Soen M, Nakano T, Takata N, Wataya T, Muguruma K, Miyoshi H, Yonemura S, Oiso Y, Sasai Y.

Nature. 480 巻 ( 7375 ) 頁： 57-62. 2011年

Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells.

Ohgushi M, Matsumura M, Eiraku M, Murakami K, Aramaki T, Nishiyama A, Muguruma K, Nakano T, Suga H, Ueno M, Ishizaki T, Suemori H, Narumiya S, Niwa H, Sasai Y.

Cell Stem Cell. 7 巻 ( 2 ) 頁： 225-239. 2010年

Urokinase-type plasminogen activator receptor is associated with the development of adipose tissue.

Kanno Y, Matsuno H, Kawashita E, Okada K, Suga H, Ueshima S, Matsuo O.

Thromb Haemost. 104 巻 ( 6 ) 頁： 1124-32. 2010年

Inflammatory cytokines regulate glycoprotein subunit beta5 of thyrostimulin through nuclear factor-kappaB.

Suzuki C, Nagasaki H, Okajima Y, Suga H, Ozaki N, Arima H, Iwasaki Y, Oiso Y

Endocrinology. 150 巻 ( 5 ) 頁： 2237-2243. 2009年

Biochemical roles of the oligosaccharide chains in thyrostimulin, a heterodimeric hormone of glycoprotein hormone subunits alpha2 (GPA2) and beta5 (GPB5).

Okajima Y, Nagasaki H, Suzuki C, Suga H, Ozaki N, Arima H, Hamada Y, Civelli O, Oiso Y.

Regul Pept. 148 巻 ( 1-3 ) 頁： 62-67. 2008年

Novel treatment for lithium induced nephrogenic diabetes insipidus rat model using the sendai-virus vector carrying aquaporin 2 gene.

Suga H, Nagasaki H, Kondo TA, Okajima Y, Suzuki C, Ozaki N, Arima H, Yamamoto T, Ozaki N, Akai M, Sato A, Uozumi N, Inoue M, Hasegawa M, Oiso Y.

Endocrinology. 149 巻 ( 11 ) 頁： 5803-5810 2008年

The LIM domain homeobox gene isl-1 is a positive regulator of glycoprotein alpha 2 (GPA2), a subunit of thyrostimulin.

Suzuki C, Nagasaki H, Okajima Y, Suga H, Arima H, Iwasaki Y, Oiso Y.

Regul Pept. 142 巻 ( 1-2 ) 頁： 60-67. 2007年

Lack of alpha2-antiplasmin improves cutaneous wound healing via over-released vascular endothelial growth factor-induced angiogenesis in wound lesions.

Kanno Y, Hirade K, Ishisaki A, Nakajima K, Suga H, Into T, Matsushita K, Okada K, Matsuo O, Matsuno H.

J Thromb Haemost. 4 巻 ( 7 ) 頁： 1602-1610. 2006年

Differential roles of MAP kinases in atorvastatin-induced VEGF release in cardiac myocytes.

Nakajima K, Suga H, Matsuno H, Ishisaki A, Hirade K, Kozawa O.

Life Sci. 79 巻 ( 12 ) 頁： 1214-1220. 2006年

Midazolam suppresses thrombin-induced heat shock protein 27 phosphorylation through inhibition of p38 mitogen-activated protein kinase in cardiac myocytes.

Tanabe K, Akamatsu S, Suga H, Takai S, Kato K, Dohi S, Kozawa O.

J Cell Biochem. 96 巻 ( 1 ) 頁： 56-64. 2005年

alphaB-crystallin is phosphorylated during myocardial infarction: involvement of platelet-derived growth factor-BB.

Shu E, Matsuno H, Akamastu S, Kanno Y, Suga H, Nakajima K, Ishisaki A, Takai S, Kato K, Kitajima Y, Kozawa O.

Arch Biochem Biophys. 438 巻 ( 2 ) 頁： 111-118. 2005年

Possible involvement of phosphatidylinositol 3-kinase/Akt signal pathway in vasopressin-induced HSP27 phosphorylation in aortic smooth muscle A10 cells.

Suga H, Nakajima K, Shu E, Kanno Y, Hirade K, Ishisaki A, Matsuno H, Tanabe K, Takai S, Akamatsu S, Kato K, Oiso Y, Kozawa O.

Arch Biochem Biophys. 438 巻 ( 2 ) 頁： 137-145. 2005年

Akt regulates thrombin-induced HSP27 phosphorylation in aortic smooth muscle cells: function at a point downstream from p38 MAP kinase.

Nakajima K, Hirade K, Ishisaki A, Matsuno H, Suga H, Kanno Y, Shu E, Kitajima Y, Katagiri Y, Kozawa O.

Life Sci. 77 巻 ( 1 ) 頁： 96-107 2005年

Vasopressin phosphorylates HSP27 in aortic smooth muscle cells.

Akamatsu S, Nakajima K, Ishisaki A, Matsuno H, Tanabe K, Takei M, Takenaka M, Hirade K, Yoshimi N, Suga H, Oiso Y, Kato K, Kozawa O.

J Cell Biochem. 92 巻 ( 6 ) 頁： 1203-1211. 2004年

Possible involvement of p44/p42 MAP kinase in retinoic acid-stimulated vascular endothelial growth factor release in aortic smooth muscle cells.

Tanabe K, Hirade K, Ishisaki A, Shu E, Suga H, Kitajima Y, Katagiri Y, Dohi S, Kozawa O.

Atherosclerosis. 175 巻 ( 2 ) 頁： 245-251. 2004年

Adrenal pseudocyst mimicking a pheochromocytoma found after a traffic accident.

Suga H, Inagaki A, Ota K, Taguchi S, Kato T, Kakiya S, Itatsu T, Yokoi K, Tsuzuki T.

Intern Med. 42 巻 ( 1 ) 頁： 66-71. 2003年

Diabetes mellitus after transplant: relationship to pretransplant glucose metabolism and tacrolimus or cyclosporine A-based therapy.

Sato T, Inagaki A, Uchida K, Ueki T, Goto N, Matsuoka S, Katayama A, Haba T, Tominaga Y, Okajima Y, Ohta K, Suga H, Taguchi S, Kakiya S, Itatsu T, Kobayashi T, Nakao A.

Transplantation. 76 巻 ( 9 ) 頁： 1320-1326. 2003年

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