研究者詳細 - 森　健策

論文 - 森　健策

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人工知能時代の医療を考える

森　健策

EAJ NEWS「AI×医療」特集号 ( 181 ) 頁： 6-8 2019年10月

Precise estimation of renal vascular dominant regions using spatially aware fully convolutional networks, tensor-cut and Voronoi diagrams

Chenglong Wang, Holger R. Roth, Takayuki Kitasaka, Masahiro Oda, Yuichiro Hayashi, Yasushi Yoshino, Tokunori Yamamoto, Naoto Sassa, Momokazu Goto, Kensaku Mori

Computerized Medical Imaging and Graphics 77 巻 ( 10642 ) 頁： 1-13 2019年10月

Spaciousness Filters for Non-contrast CT Volume Segmentation of the Intestine Region for Emergency Ileus Diagnosis

Hirohisa Oda, Kohei Nishio, Takayuki Kitasaka, Benjamin Villard, Hizuru Amano, Kosuke Chiba, Akinari Hinoki, Hiroo Uchida, Kojiro Suzuki, Hayato Itoh, Masahiro Oda, Kensaku Mori

LNCS 11840 頁： 104-114 2019年10月

Unsupervised Segmentation of Micro-CT Images of Lung Cancer Specimen Using Deep Generative Models

Takayasu Moriya, Hirohisa Oda, Midori Mitarai, Shota Nakamura, Holger R. Roth, Masahiro Oda, Kensaku Mori,

LNCS11769 頁： 240-248 2019年10月

Tubular Structure Segmentation Using Spatial Fully Connected Network With Radial Distance Loss for 3D Medical images

Chenglong Wang, Yuichiro Hayashi, Masahiro Oda, Hayato Itoh, Takayuki Kitasaka, Alejandro Frangi, Kensaku Mori

LNCS11769 頁： 348-356 2019年10月

Intelligent Image Synthesis to Attack a segmentation CNN Using Adversarial Learning

Liang Chen, Paul Bentley, Kensaku Mori, Kazunari Misawa, Michitaka Fujiwara, Daniel Rueckert,

LNCS11827 頁： 90-99 2019年10月

Artificial Intelligence-assisted System Improves Endoscopic Identification of Colorectal Neoplasms 査読有り国際誌

Kudo S.e., Misawa M., Mori Y., Hotta K., Ohtsuka K., Ikematsu H., Saito Y., Takeda K., Nakamura H., Ichimasa K., Ishigaki T., Toyoshima N., Kudo T., Hayashi T., Wakamura K., Baba T., Ishida F., Inoue H., Itoh H., Oda M., Mori K.

Clinical Gastroenterology and Hepatology 18 巻 ( 8 ) 頁： 1874 - 1881 2019年9月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Clinical Gastroenterology and Hepatology

Background & Aims: Precise optical diagnosis of colorectal polyps could improve the cost-effectiveness of colonoscopy and reduce polypectomy-related complications. However, it is difficult for community-based non-experts to obtain sufficient diagnostic performance. Artificial intelligence-based systems have been developed to analyze endoscopic images; they identify neoplasms with high accuracy and low interobserver variation. We performed a multi-center study to determine the diagnostic accuracy of EndoBRAIN, an artificial intelligence-based system that analyzes cell nuclei, crypt structure, and microvessels in endoscopic images, in identification of colon neoplasms. Methods: The EndoBRAIN system was initially trained using 69,142 endocytoscopic images, taken at 520-fold magnification, from patients with colorectal polyps who underwent endoscopy at 5 academic centers in Japan from October 2017 through March 2018. We performed a retrospective comparative analysis of the diagnostic performance of EndoBRAIN vs that of 30 endoscopists (20 trainees and 10 experts); the endoscopists assessed images from 100 cases produced via white-light microscopy, endocytoscopy with methylene blue staining, and endocytoscopy with narrow-band imaging. EndoBRAIN was used to assess endocytoscopic, but not white-light, images. The primary outcome was the accuracy of EndoBrain in distinguishing neoplasms from non-neoplasms, compared with that of endoscopists, using findings from pathology analysis as the reference standard. Results: In analysis of stained endocytoscopic images, EndoBRAIN identified colon lesions with 96.9% sensitivity (95% CI, 95.8%–97.8%), 100% specificity (95% CI, 99.6%–100%), 98% accuracy (95% CI, 97.3%–98.6%), a 100% positive-predictive value (95% CI, 99.8%–100%), and a 94.6% negative-predictive (95% CI, 92.7%–96.1%); these values were all significantly greater than those of the endoscopy trainees and experts. In analysis of narrow-band images, EndoBRAIN distinguished neoplastic from non-neoplastic lesions with 96.9% sensitivity (95% CI, 95.8–97.8), 94.3% specificity (95% CI, 92.3–95.9), 96.0% accuracy (95% CI, 95.1–96.8), a 96.9% positive-predictive value, (95% CI, 95.8–97.8), and a 94.3% negative-predictive value (95% CI, 92.3–95.9); these values were all significantly higher than those of the endoscopy trainees, sensitivity and negative-predictive value were significantly higher but the other values are comparable to those of the experts. Conclusions: EndoBRAIN accurately differentiated neoplastic from non-neoplastic lesions in stained endocytoscopic images and endocytoscopic narrow-band images, when pathology findings were used as the standard. This technology has been authorized for clinical use by the Japanese regulatory agency and should be used in endoscopic evaluation of small polyps more widespread clinical settings. UMIN clinical trial no: UMIN000028843.

DOI： 10.1016/j.cgh.2019.09.009

Scopus

PubMed

人工知能による画像診断支援-どこまでできたか.そして,その先は？

森健策

第46回日本小児内視鏡研究会プログラム・抄録集頁： 11 2019年7月

Artificial intelligence and upper gastrointestinal endoscopy: Current status and future perspective 国際誌

Mori Yuichi, Kudo Shin-ei, Mohmed Hussein E. N., Misawa Masashi, Ogata Noriyuki, Itoh Hayato, Oda Masahiro, Mori Kensaku

DIGESTIVE ENDOSCOPY 31 巻 ( 4 ) 頁： 378 - 388 2019年7月

記述言語：日本語掲載種別：研究論文（学術雑誌）出版者・発行元：Digestive Endoscopy

With recent breakthroughs in artificial intelligence, computer-aided diagnosis (CAD) for upper gastrointestinal endoscopy is gaining increasing attention. Main research focuses in this field include automated identification of dysplasia in Barrett's esophagus and detection of early gastric cancers. By helping endoscopists avoid missing and mischaracterizing neoplastic change in both the esophagus and the stomach, these technologies potentially contribute to solving current limitations of gastroscopy. Currently, optical diagnosis of early-stage dysplasia related to Barrett's esophagus can be precisely achieved only by endoscopists proficient in advanced endoscopic imaging, and the false-negative rate for detecting gastric cancer is approximately 10%. Ideally, these novel technologies should work during real-time gastroscopy to provide on-site decision support for endoscopists regardless of their skill; however, previous studies of these topics remain ex vivo and experimental in design. Therefore, the feasibility, effectiveness, and safety of CAD for upper gastrointestinal endoscopy in clinical practice remain unknown, although a considerable number of pilot studies have been conducted by both engineers and medical doctors with excellent results. This review summarizes current publications relating to CAD for upper gastrointestinal endoscopy from the perspective of endoscopists and aims to indicate what is required for future research and implementation in clinical practice.

DOI： 10.1111/den.13317

Artificial intelligence and upper gastrointestinal endoscopy: current status and future perspective 査読有り

Yuichi Mori, Shinei Kudo, Hussein Ebaid Naeem Mohmed, Masashi Misawa, Noriyuki Ogata, Hayato Itoh, Masahiro Oda, Kensaku Mori

Digestive endoscopy 34 巻 ( 4 ) 頁： 378-388 2019年7月

内視鏡検査手術における超音波画像の利用-マルチモダリティ画像統合-

森健策

計測と制御 58 巻 ( 7 ) 頁： 541-544 2019年7月

移学習を用いた腹部 thick-slice CT 像における多臓器領域の自動抽出の初期検討

申忱, ロスホルガー, 林　雄一郎, 小田紘久, 小田昌宏, 三澤一成, 森健策

第38回日本医用画像工学会大会予稿集頁： OP4-15 2019年7月

深層学習を用いた腹腔鏡手術動画像の出血領域自動セグメンテーション

山本翔太, 小田紘久, 林雄一郎, 北坂孝幸, 小田昌宏, 伊藤雅昭, 竹下修由, 森健策

第38回日本医用画像工学会大会予稿頁： OP4-13 2019年7月

開腹手術映像における遮蔽物除去システムの VR 化

北坂孝幸, 伊藤幹也, 駒形和哉, 三澤一成, 森健策

第38回日本医用画像工学会大会予稿集頁： OP4-10 2019年7月

μ CT を用いた改良版 Cycle-GAN による臨床用 CT 像の超解像処理

鄭通, 小田紘久, 守谷享泰, 杉野貴明, 中村彰太, 小田昌弘, 森雅樹, 高畠博嗣, 名取博, 森健策

第38回日本医用画像工学会大会予稿集頁： OP4-02 2019年7月

小児腸閉塞患者の CT 像における CycleGAN を用いた電子洗浄手法の検討

西尾光平, 小田紘久, 千馬耕亮, 北坂孝幸, 伊東隼人, 小田昌宏, 檜顕成, 内田広夫, 森健策

第38回日本医用画像工学会大会予稿集頁： OP3-20 2019年7月

腹腔鏡動画像からの Fully Convolutional Network による血管領域抽出

盛満慎太郎, 小澤　卓也, 北坂孝幸, 林雄一郎, 小田昌宏, 伊藤雅昭, 竹下修由, 三澤一成, 森健策

第38回日本医用画像工学会大会予稿集頁： OP3-12 2019年7月

Generative Adversarial Frameworks を用いた腹部 CT 像における非造影像からの造影像の推定

小田昌宏, 隈丸加奈子, 青木茂樹, 森健策

第38回日本医用画像工学会大会予稿集頁： OP3-07 2019年7月

AMED 大規模データベースを用いた CT 画像解析と病変検出への応用

森健策，小田昌宏

第38回日本医用画像工学会大会予稿集頁： SY1-5 2019年7月

Polyp size classification in colorectal cancer using a Siamese network

頁： OP2-14 2019年7月

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