論文 - 永田 浩三
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Comparison of the effects of renal denervation at early or advanced stages of hypertension on cardiac, renal, and adipose tissue pathology in Dahl salt-sensitive rats 査読有り
Nagata K, Tagami K, Okuzawa T, Hayakawa M, Nomura A, Nishimura T, Ikeda K, Kitada K, Kobuchi S, Fujisawa Y, Nishiyama A, Murohara T
Hypertension Research 頁: Online ahead of print 2024年2月
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Relationship between a deep learning model and liquid-based cytological processing techniques 査読有り
Ikeda K, Sakabe N, Maruyama S, Ito C, Shimoyama Y, Oboshi W, Komene T, Yamaguchi Y, Sato S, Nagata K
Cytopathology 34 巻 ( 4 ) 頁: 308 - 317 2023年7月
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Relationship between Liquid-Based Cytology Preservative Solutions and Artificial Intelligence: Liquid-Based Cytology Specimen Cell Detection Using YOLOv5 Deep Convolutional Neural Network 査読有り
Ikeda K, Sakabe N, Maruyama S, Ito C, Shimoyama Y, Sato S, Nagata K
Acta Cytologica 66 巻 ( 6 ) 頁: 542 - 550 2022年9月
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Pharmacological inhibition of the lipid phosphatase PTEN ameliorates heart damage and adipose tissue inflammation in stressed rats with metabolic syndrome 査読有り
Ashikawa S, Komatsu Y, Kawai Y, Aoyama K, Nakano S, Cui X, Hayakawa M, Sakabe N, Furukawa N, Ikeda K, Murohara T, Nagata K
Physiological Reports 10 巻 ( 1 ) 頁: e15165 2022年1月
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Characterizing the Effect of Processing Technique and Solution Type on Cytomorphology Using Liquid-Based Cytology 査読有り
Ikeda K, Oboshi W, Hashimoto Y, Komene T, Yamaguchi Y, Sato S, Maruyama S, Furukawa N, Sakabe N, Nagata K
Acta Cytologica 66 巻 ( 1 ) 頁: 55 - 60 2021年10月
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Surgical ablation of whitened interscapular brown fat ameliorates cardiac pathology in salt-loaded metabolic syndrome rats 査読有り
Komatsu Y, Aoyama K, Yoneda M, Ito S, Sano Y, Kawai Y, Cui X, Yamada Y, Furukawa N, Ikeda K, Nagata K
Annals of the New York Academy of Sciences 1492 巻 ( 1 ) 頁: 11 - 26 2021年5月
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The prebiotic fiber inulin ameliorates cardiac, adipose tissue, and hepatic pathology but exacerbates hypertriglyceridemia in rats with metabolic syndrome 査読有り
Komatsu Y, Aoyama K, Yoneda M, Ashikawa S, Nakano S, Kawai Y, Cui X, Furukawa N, Ikeda K, Nagata K
American Journal of Physiology Heart and Circulatory Physiology 320 巻 ( 1 ) 頁: H281-H295 2021年1月
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Alleviation of salt-induced exacerbation of cardiac, renal, and visceral fat pathology in rats with metabolic syndrome by surgical removal of subcutaneous fat 査読有り
Aoyama K, Komatsu Y, Yoneda M, Nakano S, Ashikawa S, Kawai Y, Cui X, Ikeda K, Nagata K
Nutrition & Diabetes 10 巻 ( 1 ) 頁: 28 2020年8月
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次世代リーダーを育成するための臨床検査技師教育のあるべき姿とそれに向けた取組み―国立大学の立場から 招待有り
永田浩三
臨床検査技師教育 11 巻 ( 1 ) 頁: 73-77 2019年3月
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Overexpression of collagen type III in injured myocardium prevents cardiac systolic dysfunction by changing the balance of collagen distribution 査読有り
Uchinaka A, Yoshida M, Tanaka K, Hamada Y, Mori S, Maeno Y, Miyagawa S, Sawa Y, Nagata K, Yamamoto H, Kawaguchi N
The Journal of Thoracic and Cardiovascular Surgery 156 巻 ( 1 ) 頁: 217-226 2018年7月
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Effects of ramelteon on cardiac injury and adipose tissue pathology in rats with metabolic syndrome 査読有り
Uchinaka A, Kawashima Y, Sano Y, Ito S, Sano Y, Nagasawa K, Matsuura N, Yoneda M, Yamada Y, Murohara T, Nagata K
Annals of the New York Academy of Sciences 1421 巻 ( 1 ) 頁: 73-87 2018年6月
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Anti-inflammatory effects of heat-killed Lactobacillus plantarum L-137 on cardiac and adipose tissue in rats with metabolic syndrome 査読有り
Uchinaka A, Azuma N, Mizumoto H, Nakano S, Minamiya M, Yoneda M, Aoyama K, Komatsu Y, Yamada Y, Murohara T, Nagata K
Scientific Reports 8 巻 ( 1 ) 頁: 8156 2018年5月
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Evaluation of dermal wound healing activity of synthetic peptide SVVYGLR 査読有り
Uchinaka A, Kawaguchi N, Ban T, Hamada Y, Mori S, Maeno Y, Sawa Y, Nagata K, Yamamoto H
Biochemical and Biophysical Research Communications 491 巻 ( 3 ) 頁: 714-720 2017年9月
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Atorvastatin reduces cardiac and adipose tissue inflammation in rats with metabolic syndrome 査読有り
Yamada Y, Takeuchi S, Yoneda M, Ito S, Sano Y, Nagasawa K, Matsuura N, Uchinaka A, Murohara T, Nagata K
International Journal of Cardiology 240 巻 頁: 332-338 2017年8月
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Effects of mTOR inhibition on cardiac and adipose tissue pathology and glucose metabolism in rats with metabolic syndrome 査読有り
Uchinaka A, Yoneda M, Yamada Y, Murohara T, Nagata K
Pharmacology Research & Perspectives 5 巻 ( 4 ) 頁: e00331 2017年8月
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Laminin α2-secreting fibroblasts enhance the therapeutic effect of skeletal myoblast sheets 査読有り
Uchinaka A, Tasaka K, Mizuno Y, Maeno Y, Ban T, Mori S, Hamada Y, Miyagawa S, Saito A, Sawa Y, Matsuura N, Nagata K, Yamamoto H, Kawaguchi N
European Journal of Cardio-Thoracic Surgery 51 巻 ( 3 ) 頁: 457-464 2017年5月
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Effects of various types of anesthesia on hemodynamics, cardiac function, and glucose and lipid metabolism in rats 査読有り
Sano Y, Ito S, Yoneda M, Nagasawa K, Matsuura N, Yamada Y, Uchinaka A, Bando YK, Murohara T, Nagata K
American Journal of Physiology Heart and Circulatory Physiology 311 巻 ( 6 ) 頁: H1360-H1366 2016年12月
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Highly purified eicosapentaenoic acid ameliorates cardiac injury and adipose tissue inflammation in a rat model of metabolic syndrome 査読有り
Ito S, Sano Y, Nagasawa K, Matsuura N, Yamada Y, Uchinaka A, Murohara T, Nagata K
Obesity Science & Practice 2 巻 ( 3 ) 頁: 318-329 2016年9月
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Attenuation of cold stress-induced exacerbation of cardiac and adipose tissue pathology and metabolic disorders in a rat model of metabolic syndrome by the glucocorticoid receptor antagonist RU486 査読有り
Nagasawa K, Matsuura N, Takeshita Y, Ito S, Sano Y, Yamada Y, Uchinaka A, Murohara T, Nagata K
Nutrition & Diabetes 6 巻 頁: e207 2016年4月
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Blockade of glucocorticoid receptors with RU486 attenuates cardiac damage and adipose tissue inflammation in a rat model of metabolic syndrome 査読有り
Takeshita Y, Watanabe S, Hattori T, Nagasawa K, Matsuura N, Takahashi K, Murohara T, Nagata K
Hypertension Research 38 巻 ( 11 ) 頁: 741-750 2015年11月
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Restraint stress exacerbates cardiac and adipose tissue pathology via β-adrenergic signaling in rats with metabolic syndrome 査読有り
Matsuura N, Nagasawa K, Minagawa Y, Ito S, Sano Y, Yamada Y, Hattori T, Watanabe S, Murohara T, Nagata K
American Journal of Physiology Heart and Circulatory Physiology 308 巻 ( 10 ) 頁: H1275-H1286 2015年5月
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Roles of oxidative stress and the mineralocorticoid receptor in cardiac pathology in a rat model of metabolic syndrome 査読有り
Takahashi K, Murase T, Takatsu M, Matsuura N, Nagasawa K, Hattori T, Watanabe S, Murohara T, Nagata K
Nagoya Journal of Medical Science 77 巻 ( 1-2 ) 頁: 275-289 2015年2月
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Effects of pioglitazone on cardiac and adipose tissue pathology in rats with metabolic syndrome 査読有り
Matsuura N, Asano C, Nagasawa K, Ito S, Sano Y, Minagawa Y, Yamada Y, Hattori T, Watanabe S, Murohara T, Nagata K
International Journal of Cardiology 179 巻 頁: 360-369 2015年1月
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Comparative effects of valsartan in combination with cilnidipine or amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats 査読有り
Nagasawa K, Takahashi K, Matsuura N, Takatsu M, Hattori T, Watanabe S, Harada E, Niinuma K, Murohara T, Nagata K
Hypertension Research 38 巻 ( 1 ) 頁: 39-47 2015年1月
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Dietary salt restriction improves cardiac and adipose tissue pathology independently of obesity in a rat model of metabolic syndrome 査読有り
Hattori T, Murase T, Takatsu M, Nagasawa K, Matsuura N, Watanabe S, Murohara T, Nagata K
Journal of the American Heart Association 3 巻 ( 6 ) 頁: e001312 2014年12月
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Elevated C-reactive protein levels and enhanced high frequency vasomotion in patients with ischemic heart disease during brachial flow-mediated dilation 査読有り
Watanabe S, Amiya E, Watanabe M, Takata M, Ozeki A, Watanabe A, Kawarasaki S, Nakao T, Hosoya Y, Nagata K, Nagai R, Komuro I
PLoS One 9 巻 ( 10 ) 頁: e110013 2014年10月
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Generation of rat-induced pluripotent stem cells from a new model of metabolic syndrome 査読有り
Takenaka-Ninagawa N, Kawabata Y, Watanabe S, Nagata K, Torihashi S
PLoS One 9 巻 ( 8 ) 頁: e104462 2014年8月
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Premature cardiac senescence in DahlS.Z-Leprfa/Leprfa rats as a new animal model of metabolic syndrome 査読有り
Takahashi K, Takatsu M, Hattori T, Murase T, Ohura S, Takeshita Y, Watanabe S, Murohara T, Nagata K
Nagoya Journal of Medical Science 76 巻 ( 1-2 ) 頁: 35-49 2014年2月
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Effects of salt status and blockade of mineralocorticoid receptors on aldosterone-induced cardiac injury 査読有り
Hattori T, Murase T, Sugiura Y, Nagasawa K, Takahashi K, Ohtake M, Ohtake M, Miyachi M, Murohara T, Nagata K
Hypertension Research 37 巻 ( 2 ) 頁: 125-133 2014年2月
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Glucocorticoids activate cardiac mineralocorticoid receptors in adrenalectomized Dahl salt-sensitive rats 査読有り
Ohtake M, Hattori T, Murase T, Takahashi K, Takatsu M, Ohtake M, Miyachi M, Watanabe S, Cheng XW, Murohara T, Nagata K
Nagoya Journal of Medical Science 76 巻 ( 1-2 ) 頁: 59-72 2014年2月
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Calorie restriction attenuates cardiac remodeling and diastolic dysfunction in a rat model of metabolic syndrome 査読有り
Takatsu M, Nakashima C, Takahashi K, Murase T, Hattori T, Ito H, Murohara T, Nagata K
Hypertension 62 巻 ( 5 ) 頁: 957-965 2013年11月
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Effects of aged garlic extract on left ventricular diastolic function and fibrosis in a rat hypertension model 査読有り
Hara Y, Noda A, Miyata S, Minoshima M, Sugiura M, Kojima J, Otake M, Furukawa M, Cheng XW, Nagata K, Murohara T
Experimental Animals 62 巻 ( 4 ) 頁: 305-310 2013年10月
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Glucocorticoid-induced hypertension and cardiac injury: effects of mineralocorticoid and glucocorticoid receptor antagonism 査読有り
Hattori T, Murase T, Iwase E, Takahashi K, Ohtake M, Tsuboi K, Ohtake M, Miyachi M, Murohara T, Nagata K
Nagoya Journal of Medical Science 75 巻 ( 1,2 ) 頁: 81-92 2013年2月
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新規メタボリック症候群ラットモデルを用いた高頻度対低頻度の運動トレーニングの心血管効果の比較検討 査読有り
中島千恵子、高津美和、杉山大輔、辻村杏理沙、村井翔太郎、矢島美希、高橋圭司、村瀬珠代、服部拓哉、加藤洋介、室原豊明、永田浩三
心臓 45 巻 ( 2 ) 頁: 147-158 2013年2月
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循環器専門医が考える高血圧合併症のリスク管理(高血圧と心肥大形成・心不全発症)―心肥大を呈する高血圧におけるCa拮抗薬の心保護効果― 招待有り
永田浩三
循環plus 13 巻 ( 4 ) 頁: 7-9 2013年1月
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Dipeptidyl Peptidase-4 Modulates Left Ventricular Dysfunction in Chronic Heart Failure via Angiogenesis-Dependent and -Independent Actions 査読有り
Shigeta T, Aoyama M, Bando YK, Monji A, Mitsui T, Takatsu M, Cheng XW, Okumura T, Hirashiki A, Nagata K, Murohara T
Circulation 126 巻 ( 15 ) 頁: 1838-1851 2012年10月
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Comparison of the effects of cilnidipine and amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats 査読有り
Takatsu M, Hattori T, Murase T, Ohtake M, Kato M, Nashima K, Nakashima C, Takahashi K, Ito H, Niinuma K, Aritomi S, Murohara T, Nagata K
Journal of Hypertension 30 巻 ( 9 ) 頁: 1845-55 2012年9月
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Effects of estrogen on cardiovascular injury in ovariectomized female DahlS.Z-Leprfa/Leprfa rats as a new animal model of metabolic syndrome 査読有り
Murase T, Hattori T, Ohtake M, Nakashima C, Takatsu M, Murohara T, Nagata K
Hypertension 59 巻 ( 3 ) 頁: 694-704 2012年3月
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Cardiac remodeling and diastolic dysfunction in DahlS.Z-Leprfa/Leprfa rats: a new animal model of metabolic syndrome 査読有り
Murase T, Hattori T, Ohtake M, Abe M, Amakusa Y, Takatsu M, Murohara T, Nagata K
Hypertension Research 35 巻 ( 2 ) 頁: 186-93 2012年2月
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Angiotensin-converting enzyme inhibition promotes coronary angiogenesis in the failing heart of Dahl salt-sensitive hypertensive rats 査読有り
Yazawa H, Miyachi M, Furukawa M, Takahashi K, Takatsu M, Tsuboi K, Ohtake M, Murase T, Hattori T, Kato Y, Murohara T, Nagata K
Journal of Cardiac Failure 17 巻 ( 12 ) 頁: 1041-1050 2011年12月
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Cardioprotective mechanisms of lifestyle modifications and pharmacotherapies on cardiac remodeling and dysfunction in hypertensive heart disease: An overview 招待有り 査読有り
Nagata K, Hattori T
Nagoya Journal of Medical Science 73 巻 ( 3-4 ) 頁: 91-105 2011年8月
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Mechanism underlying the efficacy of combination therapy with losartan and hydrochlorothiazide in rats with salt-sensitive hypertension 査読有り
Yamada Y, Tsuboi K, Hattori T, Murase T, Ohtake M, Furukawa M, Ueyama J, Nishiyama A, Murohara T, Nagata K
Hypertension Research 34 巻 ( 7 ) 頁: 809-816 2011年7月
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Characterization of a new animal model of metabolic syndrome: the DahlS.Z-Leprfa/Leprfa rat 査読有り
Hattori T, Murase T, Ohtake M, Inoue T, Tsukamoto H, Takatsu M, Kato Y, Hashimoto K, Murohara T, Nagata K
Nutrition and Diabetes 1 巻 頁: e1 2011年1月
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Ca2+ channel blocker benidipine promotes coronary angiogenesis and reduces both left-ventricular diastolic stiffness and mortality in hypertensive rats 査読有り
Nishizawa T, Cheng XW, Jin Z, Obata K, Nagata K, Hirashiki A, Sasaki T, Noda A, Takeshita K, Izawa H, Shi GP, Kuzuya M, Okumura K, Murohara T
Journal of Hypertension 28 巻 ( 7 ) 頁: 1515-26 2010年7月
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Adiponectin acts as a positive indicator of left ventricular diastolic dysfunction in patients with hypertrophic cardiomyopathy 査読有り
Unno K, Shibata R, Izawa H, Hirashiki A, Murase Y, Yamada T, Kobayashi M, Noda A, Nagata K, Ouchi N, Murohara T, Murohara T
Heart 96 巻 ( 5 ) 頁: 357-361 2010年3月
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Plasma resistin concentration determined by common variants in the resistin gene and associated with metabolic traits in an aged Japanese population 査読有り
Asano H, Izawa H, Nagata K, Nakatochi M, Kobayashi M, Hirashiki A, Shintani S, Nishizawa T, Tanimura D, Naruse K, Matsubara T, Murohara T, Yokota M
Diabetologia 53 巻 ( 2 ) 頁: 234-246 2010年2月
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Beneficial effects of growth hormone-releasing peptide on myocardial oxidative stress and left ventricular dysfunction in dilated cardiomyopathic hamsters 査読有り
Kato Y, Iwase M, Ichihara S, Kanazawa H, Hashimoto K, Noda A, Nagata K, Koike Y, Yokota M
Circulation Journal 74 巻 ( 1 ) 頁: 163-170 2010年1月
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Evidence for the importance of adiponectin in the cardioprotective effects of pioglitazone 査読有り
Li P, Shibata R, Unno K, Shimano M, Furukawa M, Ohashi T, Cheng X, Nagata K, Ouchi N, Murohara T
Hypertension 55 巻 ( 1 ) 頁: 69-75 2010年1月
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Mutation of ARHGAP9 in patients with coronary spastic angina 査読有り
Takefuji M, Asano H, Mori K, Amano M, Kato K, Watanabe T, Morita Y, Katsumi A, Itoh T, Takenawa T, Hirashiki A, Izawa H, Nagata K, Hirayama H, Takatsu F, Naoe T, Yokota M, Kaibuchi K
Journal of Human Genetics 55 巻 ( 1 ) 頁: 42-49 2010年1月
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Endomyocardial Radial Strain Imaging and Left Ventricular Relaxation Abnormalities in Patients With Hypertrophic Cardiomyopathy or Hypertensive Left Ventricular Hypertrophy 査読有り
Minoshima M, Noda A, Nishizawa T, Hara Y, Sugiura M, Iino S, Nagata K, Koike Y, Murohara T
Circulation Journal 73 巻 ( 12 ) 頁: 2294-2299 2009年12月
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Long-term administration of nifedipine attenuates cardiac remodeling and diastolic heart failure in hypertensive rats 査読有り
Yamada T, Nagata K, Cheng XW, Obata K, Saka M, Miyachi M, Naruse K, Nishizawa T, Noda A, Izawa H, Kuzuya M, Okumura K, Murohara T, Yokota M
European Journal of Pharmacology 615 巻 ( 1-3 ) 頁: 163-170 2009年8月
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Relation of functional and morphological changes in mitochondria to myocardial contractile and relaxation reserves in asymptomatic to mildly symptomatic patients with hypertrophic cardiomyopathy 査読有り
Unno K, Isobe S, Izawa H, Cheng XW, Kobayashi M, Hirashiki A, Yamada T, Harada K, Ohshima S, Noda A, Nagata K, Kato K, Yokota M, Murohara T
European Heart Journal 30 巻 ( 15 ) 頁: 1853-1862 2009年8月
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Mechanism of diastolic stiffening of the failing myocardium and its prevention by angiotensin receptor and calcium channel blockers 査読有り
Cheng XW, Okumura K, Kuzuya M, Jin Z, Nagata K, Obata K, Inoue A, Hirashiki A, Takeshita K, Unno K, Harada K, Shi GP, Yokota M, Murohara T
Journal of Cardiovascular Pharmacology 54 巻 ( 1 ) 頁: 47-56 2009年7月
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Beneficial effects of torasemide on systolic wall stress and sympathetic nervous activity in asymptomatic or mildly symptomatic patients with heart failure: comparison with azosemide 査読有り
Harada K, Izawa H, Nishizawa T, Hirashiki A, Murase Y, Kobayashi M, Isobe S, Cheng XW, Noda A, Nagata K, Yokota M, Murohara T
Journal of Cardiovascular Pharmacology 53 巻 ( 6 ) 頁: 468-473 2009年6月
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Response to exercise generates lactate and fluid intake; effects on mitochondrial function in heart and vascular smooth muscle 招待有り 査読有り
Miyachi M, Nagata K
Hypertension 54 巻 頁: e15 2009年6月
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Exercise training alters left ventricular geometry and attenuates heart failure in Dahl salt-sensitive hypertensive rats 査読有り
Miyachi M, Yazawa H, Furukawa M, Tsuboi K, Ohtake M, Nishizawa T, Hashimoto K, Yokoi T, Kojima T, Murate T, Yokota M, Murohara T, Koike Y, Nagata K
Hypertension 53 巻 ( 4 ) 頁: 701-707 2009年4月
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Dobutamine stress testing as a diagnostic tool for evaluation of myocardial contractile reserve in asymptomatic or mildly symptomatic patients with dilated cardiomyopathy 査読有り
Kobayashi M, Izawa H, Cheng XW, Asano H, Hirashiki A, Unno K, Ohshima S, Yamada T, Murase Y, Kato TS, Obata K, Noda A, Nishizawa T, Isobe S, Nagata K, Matsubara T, Murohara T, Yokota M
JACC: Cardiovascular Imaging 1 巻 ( 6 ) 頁: 718-726 2008年11月
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Heterogeneity of regional systolic function detected by tissue doppler imaging is linked to impaired global left ventricular relaxation in hypertrophic cardiomyopathy
Kato TS, Izawa H, Komamura K, Noda A, Asano H, Nagata K, Hashimoto S, Oda N, Kamiya C, Kanzaki H, Hashimura K, Nakatani T, Ueda HI, Murohara T, Kitakaze M, Yokota M
Heart 94 巻 ( 10 ) 頁: 1302-1306 2008年10月
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Superoxide-dependent cathepsin activation is associated with hypertensive myocardial remodeling and represents a target for angiotensin II type 1 receptor blocker treatment 査読有り
Cheng XW, Murohara T, Kuzuya M, Izawa H, Sasaki T, Obata K, Nagata K, Nishizawa T, Kobayashi M, Yamada T, Kim W, Sato K, Shi GP, Okumura K, Yokota M
American Journal of Pathology 173 巻 ( 2 ) 頁: 358-369 2008年8月
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Pioglitazone attenuates cardiac hypertrophy in rats with salt-sensitive hypertension: role of activation of AMP-activated protein kinase and inhibition of Akt 査読有り
Kato MF, Shibata R, Obata K, Miyachi M, Yazawa H, Tsuboi K, Yamada T, Nishizawa T, Noda A, Cheng XW, Murate T, Koike Y, Murohara T, Yokota M, Nagata K
Journal of Hypertension 26 巻 ( 8 ) 頁: 1669-1676 2008年8月
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Mineralocorticoid antagonism and cardiac hypertrophy 招待有り 査読有り
Nagata K
Current Hypertension Reports 10 巻 ( 3 ) 頁: 216-221 2008年6月
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Molecular defects associated with antithrombin deficiency and dilated cardiomyopathy in a Japanese patient 査読有り
Fujimori Y, Okimatsu H, Kashiwagi T, Sanda N, Okumura K, Takagi A, Nagata K, Murate T, Uchida A, Node K, Saito H, Kojima T
Internal Medicine 47 巻 ( 10 ) 頁: 925-931 2008年5月
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Xanthine oxidase inhibition improves left ventricular dysfunction in dilated cardiomyopathic hamsters 査読有り
Hayashi K, Kimata H, Obata K, Matsushita A, Fukata A, Hashimoto K, Noda A, Iwase M, Koike Y, Yokota M, Nagata K
Journal of Cardiac Failure 14 巻 ( 3 ) 頁: 238-244 2008年4月
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Aldosterone modulates If current through gene expression in cultured neonatal rat ventricular myocytes 査読有り
Muto T, Ueda N, Opthof T, Ohkusa T, Nagata K, Suzuki S, Tsuji Y, Horiba M, Lee JK, Honjo H, Kamiya K, Kodama I, Yasui K
American Journal of Physiology Heart and Circulatory Physiology 293 巻 ( 5 ) 頁: H2710-H2718 2007年11月
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Wilms' tumor 1 message and protein expression in bone marrow failure syndrome and acute leukemia 査読有り
Iwasaki T, Sugisaki C, Nagata K, Takagi K, Takagi A, Kojima T, Ito M, Nakamura S, Naoe T, Murate T
Pathology International 57 巻 ( 10 ) 頁: 645-651 2007年10月
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Differential cardiovascular effects of endotoxin derived from Escherichia coli or Pseudomonas aeruginosa 査読有り
Matsushita A, Iwase M, Kato Y, Ichihara S, Ichihara G, Kimata H, Hayashi K, Hashimoto K, Yokoi T, Noda A, Koike Y, Yokota M, Nagata K
Experimental Animals 56 巻 ( 5 ) 頁: 339-348 2007年10月
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Diversity of the elevation of serum cardiac troponin I levels in patients during their first visit to the emergency room 査読有り
Saiki A, Iwase M, Takeichi Y, Umeda H, Ishiki R, Inagaki H, Kato Y, Nagata K, Koike Y
Circulation Journal 71 巻 ( 9 ) 頁: 1458-1462 2007年9月
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Continuous positive airway pressure improves daytime baroreflex sensitivity and nitric oxide production in patients with moderate to severe obstructive sleep apnea syndrome 査読有り
Noda A, Nakata S, Koike Y, Miyata S, Kitaichi K, Nishizawa T, Nagata K, Yasuma F, Murohara T, Yokota M
Hypertension Research 30 巻 ( 8 ) 頁: 669-676 2007年8月
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Beneficial effect of bilevel positive airway pressure on left ventricular function in ambulatory patients with idiopathic dilated cardiomyopathy and central sleep apnea-hypopnea: a preliminary study 査読有り
Noda A, Izawa H, Asano H, Nakata S, Hirashiki A, Murase Y, Iino S, Nagata K, Murohara T, Koike Y, Yokota M
Chest 131 巻 ( 6 ) 頁: 1694-1701 2007年6月
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Attenuation of ventricular hypertrophy and fibrosis in rats by pitavastatin: potential role of the RhoA-extracellular signal-regulated kinase-serum response factor signalling pathway 査読有り
Saka M, Obata K, Ichihara S, Cheng XW, Kimata H, Noda A, Izawa H, Nagata K, Yokota M
Clinical and Experimental Pharmacology and Physiology 33 巻 ( 12 ) 頁: 1164-1171 2006年12月
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Quantitative RT-PCR analysis of sphingolipid metabolic enzymes in acute leukemia and myelodysplastic syndromes 査読有り
Sobue S, Iwasaki T, Sugisaki C, Nagata K, Kikuchi R, Murakami M, Takagi A, Kojima T, Banno Y, Akao Y, Nozawa Y, Kannagi R, Suzuki M, Abe A, Naoe T, Murate T
Leukemia 20 巻 ( 11 ) 頁: 2042-2046 2006年11月
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Elastolytic cathepsin induction/activation system exists in myocardium and is upregulated in hypertensive heart failure 査読有り
Cheng XW, Obata K, Kuzuya M, Izawa H, Nakamura K, Asai E, Nagasaka T, Saka M, Kimata T, Noda A, Nagata K, Jin H, Shi GP, Iguchi A, Murohara T, Yokota M
Hypertension 48 巻 ( 5 ) 頁: 979-987 2006年11月
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Differential myolysis of myocardium and skeletal muscle in hamsters with dilated cardiomyopathy 査読有り
Kato Y, Iwase M, Takagi K, Nishizawa T, Kanazawa H, Matsushita A, Umeda H, Izawa H, Noda A, Koike Y, Nagata K, Yokota M
Circulation Journal 70 巻 ( 11 ) 頁: 1497-1502 2006年11月
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Attenuation of cardiac dysfunction by a PPAR-alpha agonist is associated with down-regulation of redox-regulated transcription factors 査読有り
Ichihara S, Obata K, Yamada Y, Nagata K, Noda A, Ichihara G, Yamada A, Kato T, Izawa H, Murohara T, Yokota M
Journal of Molecular and Cellular Cardiology 41 巻 ( 2 ) 頁: 318-329 2006年8月
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狭心症治療薬ニコランジルの多面的効果 招待有り
永田浩三,小畑孝ニ,横田充弘
循環器科 60 巻 ( 2 ) 頁: 148-156 2006年8月
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Pitavastatin improves cardiac function and survival in association with suppression of the myocardial endothelin system in a rat model of hypertensive heart failure 査読有り
Saka M, Obata K, Ichihara S, Cheng XW, Kimata H, Nishizawa T, Noda A, Izawa H, Nagata K, Murohara T, Yokota M
Journal of Cardiovascular Pharmacology 47 巻 ( 6 ) 頁: 770-779 2006年6月
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Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and failure in low-aldosterone hypertensive rats 査読有り
Nagata K, Obata K, Xu J, Ichihara S, Noda A, Kimata H, Kato T, Izawa H, Murohara T, Yokota M
Hypertension 47 巻 ( 4 ) 頁: 656-664 2006年4月
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Prognostic value of pacing-induced mechanical alternans in patients with mild-to-moderate idiopathic dilated cardiomyopathy in sinus rhythm 査読有り
Hirashiki A, Izawa H, Somura F, Obata K, Kato T, Nishizawa T, Yamada A, Asano H, Ohshima S, Noda A, Iino S, Nagata K, Okumura K, Murohara T, Yokota M
Journal of the American College of Cardiology 47 巻 ( 7 ) 頁: 1382-1389 2006年4月
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The distal protection during primary percutaneous coronary intervention alleviates the adverse effects of large thrombus burden on myocardial reperfusion 査読有り
Umeda H, Katoh T, Iwase M, Izawa H, Nagata K, Watanabe K, Okada T, Yamada T, Tani T, Matsushita T, Murakami Y, Okamoto M, Shimizu T, Murohara T, Yokota M
Circulation Journal 70 巻 ( 3 ) 頁: 232-238 2006年3月
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Pravastatin increases survival and suppresses an increase in myocardial matrix metalloproteinase activity in a rat model of heart failure 査読有り
Ichihara S, Noda A, Nagata K, Obata K, Xu J, Ichihara G, Oikawa S, Kawanishi S, Yamada Y, Yokota M
Cardiovascular Research 69 巻 ( 3 ) 頁: 726-735 2006年2月
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Overexpression of calmodulin induces cardiac hypertrophy by a calcineurin-dependent pathway 査読有り
Koji Obata, Kohzo Nagata, Mitsunori Iwase, Mari Odashima, Tetsuro Nagasaka, Hideo Izawa, Toyoaki Murohara, Yoshiji Yamada, Mitsuhiro Yokota
Biochemical and Biophysical Research Communications 338 巻 ( 2 ) 頁: 1299-1305 2005年12月
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Cardiac sympathetic dysfunction correlates with abnormal myocardial contractile reserve in dilated cardiomyopathy patients 査読有り
Satoru Ohshima, Satoshi Isobe, Hideo Izawa, Mamoru Nanasato, Akitada Ando, Akira Yamada, Kiyoyasu Yamada, Tomoko Kato, Koji Obata, Akiko Noda, Takao Nishizawa, Katsuhiko Kato, Kohzo Nagata, Kenji Okumura, Toyoaki Murohara, Mitsuhiro Yokota
Journal of the American College of Cardiology 46 巻 ( 11 ) 頁: 2061-2068. 2005年12月
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Mineralocorticoid receptor antagonism ameliorates left ventricular diastolic dysfunction and myocardial fibrosis in mildly symptomatic patients with idiopathic dilated cardiomyopathy: a pilot study 査読有り
Izawa H, Murohara T, Nagata K, Isobe S, Asano H, Amano T, Ichihara S, Kato T, Ohshima S, Murase Y, Iino S, Obata K, Noda A, Okumura K, Yokota M
Circulation 112 巻 ( 19 ) 頁: 2940-2945 2005年11月
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Nicorandil promotes myocardial capillary and arteriolar growth in the failing heart of Dahl salt-sensitive hypertensive rats 査読有り
Jinglan Xu, Kohzo Nagata, Koji Obata, Sahoko Ichihara, Hideo Izawa, Akiko Noda, Tetsuro Nagasaka, Mitsunori Iwase, Toyoaki Murohara, Mitsuhiro Yokota
Hypertension 46 巻 ( 4 ) 頁: 719-24 2005年10月
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Cardiac 123I-MIBG reflects left ventricular functional reserve in patients with nonobstructive hypertrophic cardiomyopathy 査読有り
Satoshi Isobe, Hideo Izawa, Mitsunori Iwase, Mamoru Nanasato, Makoto Nonokawa, Akitada Ando, Satoru Ohshima, Kohzo Nagata, Katsuhiko Kato, Takao Nishizawa, Toyoaki Murohara, Mitsuhiro Yokota
Journal of Nuclear Medicine 46 巻 ( 6: ) 頁: 909-916 2005年6月
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Discrimination of nonobstructive hypertrophic cardiomyopathy from hypertensive left ventricular hypertrophy on the basis of strain rate imaging by tissue Doppler ultrasonography 査読有り
Tomoko S. Kato, Akiko Noda, Hideo Izawa, Akira Yamada, Koji Obata, Kohzo Nagata, Mitsunori Iwase, Toyoaki Murohara, Mitsuhiro Yokota
Circulation 110 巻 ( 25 ) 頁: 3808-3814 2004年12月
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Serial alterations of β-adrenergic signaling in dilated cardiomyopathic hamsters: possible role of myocardial oxidative stress 査読有り
Takao Nishizawa, Mitsunori Iwase, Hiroaki Kanazawa, Sahoko Ichihara, Gaku Ichihara, Kohzo Nagata, Koji Obata, Kiyoyuki Kitaichi, Toyoharu Yokoi, Masato Watanabe, Takashi Tsunematsu, Yoshihiro Ishikawa, Toyoaki Murohara, Mitsuhiro Yokota
Circulation Journal 68 巻 ( 11 ) 頁: 1051-1060 2004年11月
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Lack of association of polymorphisms of the lymphotoxin α gene with myocardial infarction in Japanese 査読有り
Akira Yamada, Sahoko Ichihara, Yosuke Murase, Tomoko Kato, Hideo Izawa, Kohzo Nagata, Toyoaki Murohara, Yoshiji Yamada, Mitsuhiro Yokota
Journal of Molecular Medicine 82 巻 ( 7 ) 頁: 477-483 2004年7月
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Blunt circulatory response to exercise in coronary high-risk subjects among apparently healthy Japanese 査読有り
Ichihara Y, Ohno J, Suzuki M, Anno T, Sugino M, Nagata K
Circulation Journal 68 巻 ( 4 ) 頁: 286-293 2004年4月
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Promising efficacy of primary gradual and prolonged balloon angioplasty in small coronary arteries: A randomized comparison with cutting balloon angioplasty and conventional balloon angioplasty 査読有り
Umeda H, Iwase M, Kanda H, Izawa H, Nagata K, Ishiki R, Sawada K, Murohara T, Yokota M
American Heart Journal 147 巻 ( 1 ) 頁: E4 2004年1月
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Growth hormone-releasing peptide can improve left ventricular dysfunction and attenuate dilation in dilated cardiomyopathic hamsters 査読有り
Iwase M, Kanazawa H, Kato Y, Nishizawa T, Somura F, Ishiki R, Nagata K, Hashimoto K, Takagi K, Izawa H, Yokota M
Cardiovascular Research 61 巻 ( 1 ) 頁: 30-38 2004年1月
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Association of gene polymorphisms with coronary artery disease in individuals with or without nonfamilial hypercholesterolemia 査読有り
Keiko Shimokata, Yoshiji Yamada, Takahisa Kondo, Sahoko Ichihara, Hideo Izawa, Kohzo Nagata, Toyoaki Murohara, Miyoshi Ohno, Mitsuhiro Yokota
Atherosclerosis 172 巻 ( 1 ) 頁: 167-173 2004年1月
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Nicorandil inhibits oxidative stress-induced apoptosis in cardiac myocytes through activation of mitochondrial ATP-sensitive potassium channels and a nitrate-like effect
Nagata K, Obata K, Odashima M, Yamada A, Somura F, Nishizawa T, Ichihara S, Izawa H, Iwase M, Hayakawa A, Murohara T, Yokota M
Journal of Molecular and Cellular Cardiology 35 巻 ( 12 ) 頁: 1505-1512 2003年12月
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成人病と生活習慣病:循環器疾患の非薬物治療―現状と今後の展開―心筋の再生治療 招待有り
永田浩三,横田充弘,室原豊明
成人病と生活習慣病 33 巻 ( 8 ) 頁: 931-935 2003年8月
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Biphasic relaxation-frequency relations in patients with effort angina pectoris: a new marker of myocardial demand ischemia 査読有り
Hisashi Umeda,Mitsunori Iwase,Hideo Izawa,Takao Nishizawa,Makoto Nonokawa,Satoshi Isobe,Akiko Noda,Kohzo Nagata,Hitoshi Ishihara,Mitsuhiro Yokota
American Heart Journal 146 巻 ( 1 ) 頁: 75-83 2003年7月
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Validity and application of noninvasive measurement of blood pressure in hamsters 査読有り
Yosuke Kato,Mitsunori Iwase,Hiroaki Kanazawa,Takao Nishizawa,Ying Lan Zhao,Kenji Takagi,Kohzo Nagata,Akiko Noda,Yasuo Koike,Mitsuhiro Yokota
Experimental Animals 52 巻 ( 4 ) 頁: 359-363 2003年7月
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Myocardial velocity gradient as a noninvasively determined index of left ventricular diastolic dysfunction in patients with hypertrophic cardiomyopathy 査読有り
Tomoko Kato,Akiko Noda,Hideo Izawa,Takao Nishizawa,Fuji Somura,Akira Yamada,Kohzo Nagata,Mitsunori Iwase,Akimasa Nakao,Mitsuhiro Yokota
Journal of the American College of Cardiology 42 巻 ( 2 ) 頁: 278-285 2003年7月
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Effect of nicorandil on left ventricular end-diastolic pressure during exercise in patients with hypertrophic cardiomyopathy 査読有り
Hideo Izawa,Mitsunori Iwase,Yasushi Takeichi,Fuji Somura,Kohzo Nagata,Takao Nishizawa,Akiko Noda,Toyoaki Murohara,Mitsuhiro Yokota
European Heart Journal 24 巻 ( 14 ) 頁: 1340-1348 2003年7月
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AT1 receptor blockade reduces cardiac calcineurin activity in hypertensive rats 査読有り
Nagata K, Somura F, Obata K, Odashima M, Izawa H, Ichihara S, Nagasaka T, Iwase M, Yamada Y, Nakashima N, Yokota M
Hypertension 40 巻 ( 2 ) 頁: 168-174 2002年8月
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Higher C-reactive protein concentration and white blood cell count in subjects with more coronary risk factors and/or lower physical fitness among apparently healthy Japanese
Ichihara Y, Ohno J, Suzuki M, Anno T, Sugino M, Nagata K
Circulation Journal 66 巻 ( 7 ) 頁: 677-684 2002年7月
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Effects of FK506 and rapamycin on formation of the neural tube in chick embryos 査読有り
Koji Obata,Masafumi Koide,Kohzo Nagata,Akio Iio,Shigenobu Yazawa,Tamao Ono,Shin-ichi Sasaki,Yoshiji Yamada,Rocky S.Tuan,Mitsuhiro Yokota
Animal Science Journal 73 巻 ( 3 ) 頁: 229-234 2002年6月
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Prognostic value of mechanical efficiency in ambulatory patients with idiopathic cardiomyopathy in sinus rhythm 査読有り
Il Sung Kim,Hideo Izawa,Toshikazu Sobue,Hitoshi Ishihara,Fuji Somura,Takao Nishizawa,Kohzo Nagata,Mitsunori Iwase,Mitsuhiro Yokota
Journal of the American College of Cardiology 39 巻 ( 8 ) 頁: 1264-1268 2002年4月
-
Biphasic changes in left ventricular end-diastolic pressure during dynamic exercise in patients with nonobstructive hypertrophic cardiomyopathy 査読有り
Yasushi Takeichi,Mitsuhiro Yokota,Mitsunori Iwase,Hideo Izawa,Takao Nishizawa,Ryoji Ishiki,Fuji Somura,Kohzo Nagata,Satoshi Isobe,Akiko Noda
Journal of the American College of Cardiology 38 巻 ( 2 ) 頁: 335-343 2001年8月
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Reduced myocardial sarcoplasmic reticulum Ca2+-ATPase mRNA expression and biphasic force-frequency relations in patients with hypertrophyc cardiomyopathy 査読有り
Fuji Somura,Hideo Izawa,Mitsunori Iwase,Yasushi Takeichi,Ryoji Ishiki,Takao Nishizawa,Akiko Noda,Kohzo Nagata,Yoshiji Yamada,Mitsuhiro Yokota
Circulation 104 巻 ( 6 ) 頁: 658-663 2001年8月
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Role of FK506-binding protein 12 in development of the chick embryonic heart 査読有り
Koji Obata,Masafumi Koide,Kohzo Nagata,Akio Iio,Shigenobu Yazawa,Tamao Ono,Yoshiji Yamada,Rocky S.Tuan,Mitsuhiro Yokota
Biochemical and Biophysical Research Communications 283 巻 ( 3 ) 頁: 613-620 2001年5月
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Targeted inactivation of Gαi does not alter cardiac function or β-adrenergic sensitivity 査読有り
Jain M, Lim CC, Nagata K, Davis VM, Milstone DS, Liao R, Mortensen RM
American Journal of Physiology Heart and Circulatory Physiology 280 巻 ( 2 ) 頁: H569-H575 2001年2月
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Gαi2 but not Gαi3 is required for muscarinic inhibition of contractility and calcium currents in adult cardiomyocytes 査読有り
Nagata K, Ye C, Jain M, Milstone DS, Liao R, Mortensen RM
Circulation Research 87 巻 ( 10 ) 頁: 903-909 2000年11月
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Altered β-adrenergic signal transduction in nonfailing hypertrophied myocytes from Dahl salt-sensitive rats 査読有り
Nagata K, Communal C, Lim CC, Jain M, Suter TM, Eberli FR, Satoh N, Colucci WS, Apstein CS, Liao R
American Journal of Physiology Heart and Circulatory Physiology 279 巻 ( 5 ) 頁: H2502-H2508. 2000年11月
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Different β-adrenergic regulation of myocardial contraction and relaxation between apical and nonobstructive hypertrophic cardiomyopathy 査読有り
Ping Zuo,Hideo Izawa,Ryoji Ishiki,Akiko Noda,Takao Nishizawa,Kazushige Shigemura,Kohzo Nagata,Mitsunori Iwase,Mitsuhiro Yokota
American Heart Journal 140 巻 ( 2 ) 頁: 329-337 2000年8月
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Acute effects of a single low oral dose of pimobendan on left ventricular systolic and diastolic function in patients with congestive heart failure 査読有り
Ryoji Ishiki,Hitoshi Ishihara,Hideo Izawa,Kohzo Nagata,Makoto Hirai,Mitsuhiro Yokota
Journal of Cardiovascular Pharmacology 35 巻 ( 6 ) 頁: 897-905 2000年6月
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Impaired force- frequency relations in patients with hypertensive left ventricular hypertrophy. : A possible physiological marker of the trnsition from physiologica to pathological hypertrophy 査読有り
Masafumi Inagaki,Mitsuhiro Yokota,Hideo Izawa,Ryoji Ishiki,Kohzo Nagata,Mitsunori Iwase,Yoshiji Yamada,Masafumi Koide,Toshikazu Sobue
Circulation 274 巻 ( 14 ) 頁: 1822-1830 1999年4月
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Early changes in excitation-contraction coupling: transition from compensated hypertrophy to failure in Dahl salt-sensitive rat myocytes 査読有り
Nagata K, Liao R, Eberli FR, Satoh N, Chevalier B, Apstein CS, Suter TM
Cardiovascular Research 37 巻 ( 2 ) 頁: 467-477 1998年2月
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Dynamic exercise-induced changes in diastolic properties of the regional myocarduium in hypertensive left ventricular hypertrophy 査読有り
Yasushi Takeichi,Kohzo Nagata,Hideo Izawa,Mitsunori Iwase,Toshikazau Sobue,Motoaki Sugawara,Mitsuhiro Yokota
Heart and Vessels Suppl.12 巻 頁: 138-141 1997年12月
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Adrenergic control of the force-frequency and relaxation-frequency relations in patients with hypertrophic cardiomyopathy 査読有り
Hideo Izawa,Mitsuhiro Yokota,Yasushi Takeichi,Masafumi Inagaki,Kohzo Nagata,Mitsunori Iwase,Toshikazu Sobue
Circulation 96 巻 ( 9 ) 頁: 2959-2968 1997年11月
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Effect of dobutamine and OPC-18790 on diastolic chamber stiffness in patients with idiopathic dilated cardiomyopathy 査読有り
Takeshi Machii,Mitsuhiro Yokota,Kohzo Nagata,Hitoshi Ishihara,Mitsunori Iwase,Toshikazu Sobue
Journal of Cardiovascular Pharmacology 29 巻 ( 2 ) 頁: 265-272 1997年2月
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Impaired response of left ventricular relaxation to exercise-induced adrenergic stimulation in patients with hypertrophic cardiomyopathy 査読有り
Hideo Izawa,Mitsuhiro Yokota,Kohzo Nagata,Mitsunori Iwase,Toshikazu Sobue
Journal of the American College of Cardiology 28 巻 ( 7 ) 頁: 1738-1745 1996年12月
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A novel inotropic vasodilator, OPC-18790, reduces myocardial oxygen consumption and improves mechanical efficiency with congestive heart failure 査読有り
Hirofumi Kanda,Mitsuhiro Yokota,Hitoshi Ishihara,Kohzo Nagata,Ryozo Kato,Toshikazu Sobue
American Heart Journal 132 巻 ( 2 ) 頁: 361-368 1996年8月
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Differential effects of dobutamine and a phosphodiesterase inhibitor on early diastolic filling in patients with congestive heart failure 査読有り
Nagata K, Iwase M, Sobue T, Yokota M
Journal of the American College of Cardiology 25 巻 ( 2 ) 頁: 295-304 1995年2月
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Hemodynamic effects of the calcium channel blocker pranidipine on exercise-induced angina 査読有り
Yasuto Nishinaka,Mitsuhiro Yokota,Makoto Watanabe,Toshikazu Sobue,Mitsunori Iwase,Masahiko Ukai,Akitada Ando,Kohzo Nagata,Hidehiko Saito
International Journal of Clinical Pharmacology and Therapeutics 32 巻 ( 10 ) 頁: 542-549 1994年10月
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-特集-「運動と心臓」 招待有り
横田充弘,永田浩三
CARDIAC PRACTICE 5 巻 ( 3 ) 頁: 63-68 1994年7月
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Age-related changes in left and right ventricular filling velocity profiles and their relationship in normal subjects 査読有り
Mitsunori Iwase,Kozo Nagata,Hideo Izawa,Mitsuhiro Yokota, Susumu Kamihara,Haruo Inagaki,Hidehiko Saito
American Heart Journal 126 巻 ( 2 ) 頁: 419-426 1993年8月